WordNet

be a contributing factor; "make things factor into a companys profitability"
any of the numbers (or symbols) that form a product when multiplied together
an independent variable in statistics
anything that contributes causally to a result; "a number of factors determined the outcome"
consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
a concept whose truth can be proved; "scientific hypotheses are not facts"
a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"

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1. 血管新生阻害剤の概要 overview of angiogenesis inhibitors
2. 血友病患者における第VIIIおよび第IX因子阻害物質 factor viii and factor ix inhibitors in patients with hemophilia
3. 難治性狭心症マネージメントのための血管新生療法 therapeutic angiogenesis for management of refractory angina
4. 後天性の凝固因子阻害物質 acquired inhibitors of coagulation
5. 非血友病患者における遺伝子組換え第VIIa凝固因子の治療使用 therapeutic uses of recombinant coagulation factor viia in non hemophiliacs

Shah YM1,2.
Molecular and cellular pediatrics.Mol Cell Pediatr.2016 Dec;3(1):1. doi: 10.1186/s40348-016-0030-1. Epub 2016 Jan 26.
Inflammatory bowel disease (IBD) is a chronic relapsing inflammatory disease of the intestine. IBD is a multifactorial disorder, and IBD-associated genes are critical in innate immune response, inflammatory response, autophagy, and epithelial barrier integrity. Moreover, epithelial oxygen tension pl
PMID 26812949

Amperometric sensing of HIF1α expressed in cancer cells and the effect of hypoxic mimicking agents.

Hussain KK1, Gurudatt NG1, Mir TA1, Shim YB2.
Biosensors & bioelectronics.Biosens Bioelectron.2016 Sep 15;83:312-8. doi: 10.1016/j.bios.2016.04.068. Epub 2016 Apr 22.
Hypoxia inducible factor 1 alpha (HIF1α) overexpression was detected in cancerous cells using an amperometric immunosensor with a nano-bioconjugate. The sensor probe was fabricated by covalently immobilizing the antibody (anti-HIF1α) onto a composite layer of functionalized conducting polymer [2,2
PMID 27132006

PEGylated lipid bilayer-supported mesoporous silica nanoparticle composite for synergistic co-delivery of axitinib and celastrol in multi-targeted cancer therapy.

Choi JY1, Ramasamy T1, Kim SY1, Kim J1, Ku SK2, Youn YS3, Kim JR4, Jeong JH1, Choi HG5, Yong CS6, Kim JO7.
Acta biomaterialia.Acta Biomater.2016 Jul 15;39:94-105. doi: 10.1016/j.actbio.2016.05.012. Epub 2016 May 6.
Small-molecule drug combination therapies are an attractive approach to enhancing cancer chemotherapeutic responses. Therefore, this study aimed to investigate the potential of axitinib (AXT) and celastrol (CST) in targeting angiogenesis and mitochondrial-based apoptosis in cancer. Therefore, we pre
PMID 27163403

General Anesthetics Inhibit Erythropoietin Induction under Hypoxic Conditions in the Mouse Brain.

Tanaka Tomoharu,Kai Shinichi,Koyama Tomohiro,Daijo Hiroki,Adachi Takehiko,Fukuda Kazuhiko,Hirota Kiichi
PloS one 6(12), 2011-12
… [Background]： Erythropoietin (EPO), originally identified as a hematopoietic growth factor produced in the kidney and fetal liver, is also endogenously expressed in the central nervous system (CNS). … EPO in the CNS, mainly produced in astrocytes, is induced under hypoxic conditions in a hypoxia-inducible factor (HIF)-dependent manner and plays a dominant role in neuroprotection and neurogenesis. …
NAID 120003726125

Expression of Hypoxia-inducible Factor 1α Predicts Clinical Outcome after Preoperative Hyperthermo-chemoradiotherapy for Locally Advanced Rectal Cancer

SHIOYA Mariko,TAKAHASHI Takeo,ISHIKAWA Hitoshi,SAKURAI Hideyuki,EBARA Takeshi,SUZUKI Yoshiyuki,SAITOH Jun-ichi,OHNO Tatsuya,ASAO Takayuki,KUWANO Hiroyuki,NAKANO Takashi
Journal of radiation research 52(6), 821-827, 2011-11-16
… Hypoxia-inducible factor 1α (HIF-1α) is an intrinsic marker of tumor hypoxia. … It has been considered that hypoxic conditions reduce radiosensitivity, but the role of HIF-1α in patients treated with preoperative therapy for rectal cancer is still unclear. …
NAID 10029653265