低カリウム血性ミオパチー
WordNet
- any pathology of the muscles that is not attributable to nerve dysfunction
UpToDate Contents
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English Journal
- Hypokalemic periodic paralysis induced by thymic hyperplasia and relieved by thymectomy.
- Yang R, Jurkat-Rott K, Cao J, Wang G, Seelig HP, Yang C, Liu G, Pan L, Zheng H, Lehmann-Horn F.Author information Department of Thoracic Surgery, 117 PLA Hospital, Hangzhou, China.AbstractIMPORTANCE: Hypokalemic periodic paralysis is a muscle channelopathy based on mutations or predisposing variants or secondary to potassium wasting. In contrast to myasthenia gravis, an association with thymic hyperplasia has not yet been reported, to our knowledge.
- JAMA neurology.JAMA Neurol.2013 Nov;70(11):1436-9. doi: 10.1001/jamaneurol.2013.3918.
- IMPORTANCE: Hypokalemic periodic paralysis is a muscle channelopathy based on mutations or predisposing variants or secondary to potassium wasting. In contrast to myasthenia gravis, an association with thymic hyperplasia has not yet been reported, to our knowledge.OBSERVATIONS: We report a male pati
- PMID 24061198
- Spasmodic muscle cramps and weakness as presenting symptoms in Wilson disease.
- Rosen JM, Kuntz N, Melin-Aldana H, Bass LM.Author information Children's Mercy Hospitals and Clinics, 2401 Gillham Road, Kansas City, MO 64108. jmrosen@cmh.edu.AbstractWilson disease (WD) is an autosomal-recessive disorder of hepatic copper metabolism that has tremendous variability in its presentation. Phenotypic diversity of the disease can lead to delayed diagnosis. We describe a case of WD in a 10-year-old boy presenting with 3 months of increasingly intense, spasmodic lower extremity muscle cramps. Physical examination revealed tenderness on calf palpation and dark flat lesions over his ankles, knees, and elbows. Initial testing revealed creatine kinase of 302 IU/L (normal 24-248 IU/L), hemoglobin of 8.9 g/dL (11.5-15.5 g/dL), aspartate aminotransferase of 114 IU/L (16-52 IU/L), alanine aminotransferase of 54 IU/L (2-30 IU/L), and myoglobinuria. Extensive evaluation of his myopathy, including MRI and muscle biopsy, was negative. Additional laboratory tests revealed a prothrombin time of 21.3 seconds (11.8-15.5 seconds), total bilirubin of 1.4 mg/dL (<1 mg/dL), direct bilirubin of 0.5 mg/dL (<0.3 mg/dL), albumin of 2.1 g/dL (3.1-4.6 g/dL), a reticulocyte percentage of 4.5% (0.5%-2.5%), a negative Coombs direct antibody test, ceruloplasmin of 3 mg/dL (21-51 mg/dL), and 24-h urine copper of 393 μg/24 h (15-60 μg/24 h). Liver biopsy showed patchy advanced fibrosis, mild inflammation, positive staining for copper, and a tissue copper concentration of 768 µg/g (10-35 μg/g). Brain MRI revealed symmetric intrinsic T1 shortening within bilateral basal ganglia. Trientene therapy was initiated for WD. Symptoms and laboratory abnormalities resolved and remain normal at 21 months' follow-up. Musculoskeletal involvement in WD is uncommon and typically defined as bone demineralization, arthropathy, or hypokalemic muscle weakness. In patients with unexplained musculoskeletal symptoms and hepatic abnormalities, a diagnosis of WD should be considered and appropriate evaluation initiated.
- Pediatrics.Pediatrics.2013 Oct;132(4):e1039-42. doi: 10.1542/peds.2012-2923. Epub 2013 Sep 2.
- Wilson disease (WD) is an autosomal-recessive disorder of hepatic copper metabolism that has tremendous variability in its presentation. Phenotypic diversity of the disease can lead to delayed diagnosis. We describe a case of WD in a 10-year-old boy presenting with 3 months of increasingly intense,
- PMID 23999958
- Thyrotoxic hypokalemic periodic paralysis: two case reports and a brief review of literature.
- Shah M, Mutneja R, Vyas D, Trivedi R, Silverstein N.Author information University of Connecticut Health Center, Internal Medicine, USA.AbstractThyrotoxic Hypokalemic Periodic Paralysis (THPP) is a rare complication of thyrotoxicosis and can sometimes be fatal. It needs early recognition for proper management and prevention of recurrences. Here we describe two cases presenting with acute onset of paresis, low potassium levels, low levels of thyroid-stimulating hormones (TSH), and elevated thyroid hormone levels.
- Connecticut medicine.Conn Med.2013 Sep;77(8):487-9.
- Thyrotoxic Hypokalemic Periodic Paralysis (THPP) is a rare complication of thyrotoxicosis and can sometimes be fatal. It needs early recognition for proper management and prevention of recurrences. Here we describe two cases presenting with acute onset of paresis, low potassium levels, low levels of
- PMID 24156178
Japanese Journal
- 症例報告 当帰飲子による低カリウム血症性ミオパチーを呈した高齢女性の1例
- 緑茶抽出物飲料の過剰摂取により低カリウム血性ミオパチーをきたした1例
- 症例報告 ポリスチレンスルホン酸ナトリウムおよび球形吸着炭常用による高度便秘から低カリウム性ミオパチーをきたした1例
- 藤野 靖久,井上 義博,小野寺 誠 [他]
- The Japanese journal of clinical toxicology 26(1), 49-53, 2013
- NAID 40019614166
Related Links
- myopathy /my·op·a·thy/ (mi-op´ah-the) any disease of muscle.myopath´ic centronuclear myopathy myotubular m. mitochondrial myopathy any of a group of myopathies associated with an increased number of large, often abnormal ...
- my·op·a·thy (m-p-th) n. pl. my·op·a·thies A disease of muscle or muscle tissue. my o·path ic (m-p th k) adj. myopathy (maɪˈɒpəθɪ) n, pl-thies 1. (Pathology) any disease affecting muscles or muscle tissue my•op•a•thy (maɪˈɒp ə θi) ...
- myopathy [mī′äp·ə·thē] (medicine) Any disease of the muscles. Also known as myopathia. Myopathy progressive muscular dystrophy; a hereditary disease. Myopathies can be transmitted as autosomal recessive or dominant, or sex ...
★リンクテーブル★
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- 英
- hypokalemic myopathy
- 同
- 血清カリウム欠乏性ミオパチー potassium-depletion myopathy、低カリウム性ミオパチー
- 関
- 筋疾患、低カリウム血症、カリウム
基礎疾患