WordNet
- (pathology) a small abnormal patch on or inside the body
- relating to or involving or causing hemolysis; "hemolytic anemia" (同)haemolytic
PrepTutorEJDIC
- (金属・陶器などの)飾り額,飾り板
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English Journal
- Is a booster dose necessary in children after immunization with live attenuated Japanese encephalitis vaccine?
- Choi UY, Lee SY, Kim KH, Kim DS, Choi KM, Cha SH, Kang JH.Author information Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea.AbstractJapanese encephalitis virus is a common cause of encephalitis in Asian children; therefore, maintenance of immunity against Japanese encephalitis virus is essential. Although many countries recommend booster vaccination, some trials have concluded that administration of one or two vaccinations is sufficient. The current study was conducted to evaluate immunogenicity and safety after a booster vaccination with live attenuated vaccine. For 68 study subjects, measurement of antibody titer was performed before and at 4-6 weeks after administration of a booster dose. Adverse reactions occurring at the injection site and systemic adverse reactions were documented. The percentages of subjects with seroprotective neutralizing antibody titers was 100% before and after booster vaccination, and the geometric mean titer increased after booster vaccination. Thus, we predict that immunity will be maintained for a long time by an amnestic response. Low percentages of adverse reactions indicated the safety of the immunizations.
- Journal of tropical pediatrics.J Trop Pediatr.2013 Oct;59(5):423-5. doi: 10.1093/tropej/fmt043. Epub 2013 Jun 13.
- Japanese encephalitis virus is a common cause of encephalitis in Asian children; therefore, maintenance of immunity against Japanese encephalitis virus is essential. Although many countries recommend booster vaccination, some trials have concluded that administration of one or two vaccinations is su
- PMID 23764540
- LacR mutations are frequently observed in Streptococcus intermedius and are responsible for increased intermedilysin production and virulence.
- Tomoyasu T, Imaki H, Masuda S, Okamoto A, Kim H, Waite RD, Whiley RA, Kikuchi K, Hiramatsu K, Tabata A, Nagamune H.Author information Department of Biological Science and Technology, Institute of Technology and Science, The University of Tokushima Graduate School, Tokushima, Japan.AbstractStreptococcus intermedius secretes a human-specific cytolysin, intermedilysin (ILY), which is considered to be the major virulence factor of this pathogen. We screened for a repressor of ily expression by using random gene disruption in a low-ILY-producing strain (PC574). Three independent high-ILY-producing colonies that had plasmid insertions within a gene that has high homology to lacR were isolated. Validation of these observations was achieved through disruption of lacR in strain PC574 with an erythromycin cassette, which also led to higher hemolytic activity, increased transcription of ily, and higher cytotoxicity against HepG2 cells, compared to the parental strain. The direct binding of LacR within the ily promoter region was shown by a biotinylated DNA probe pulldown assay, and the amount of ILY secreted into the culture supernatant by PC574 cells was increased by adding lactose or galactose to the medium as a carbon source. Furthermore, we examined lacR nucleotide sequences and the hemolytic activity of 50 strains isolated from clinical infections and 7 strains isolated from dental plaque. Of the 50 strains isolated from infections, 13 showed high ILY production, 11 of these 13 strains had one or more point mutations and/or an insertion mutation in LacR, and almost all mutations were associated with a marked decline in LacR function. These results strongly suggest that mutation in lacR is required for the overproduction of ILY, which is associated with an increase in pathogenicity of S. intermedius.
- Infection and immunity.Infect Immun.2013 Sep;81(9):3276-86. doi: 10.1128/IAI.00638-13. Epub 2013 Jun 24.
- Streptococcus intermedius secretes a human-specific cytolysin, intermedilysin (ILY), which is considered to be the major virulence factor of this pathogen. We screened for a repressor of ily expression by using random gene disruption in a low-ILY-producing strain (PC574). Three independent high-ILY-
- PMID 23798532
- Assessment of the immunosuppressive and hemolytic activities of an edible fern, Diplazium esculentum.
- Roy S, Tamang S, Dey P, Chaudhuri TK.Author information Cellular Immunology Laboratory, Department of Zoology, University of North Bengal, Siliguri, West Bengal, India.AbstractCONTEXT: Diplazium esculentum is the most commonly consumed fern throughout Asia and Oceania. Systemic toxicity and pathological effects on its consumption have already been demonstrated. But, the immunosuppressive and hemolytic activities of the boiled Diplazium esculentum (BDE), the form in which human consumes it, have not yet been studied.
- Immunopharmacology and immunotoxicology.Immunopharmacol Immunotoxicol.2013 Jun;35(3):365-72. doi: 10.3109/08923973.2013.775588.
- CONTEXT: Diplazium esculentum is the most commonly consumed fern throughout Asia and Oceania. Systemic toxicity and pathological effects on its consumption have already been demonstrated. But, the immunosuppressive and hemolytic activities of the boiled Diplazium esculentum (BDE), the form in which
- PMID 23672523
Japanese Journal
- Autoimmune Hemolytic Anemia during Adalimumab Treatment for Plaque Psoriasis
- Harada Yukinori,Yamamoto Hiroaki,Sato Midori,Kodaira Mutsuki,Kono Tsunesuke
- Internal Medicine 54(9), 1103-1104, 2015
- … We herein describe the case of an 85-year-old Japanese man with plaque psoriasis who developed autoimmune hemolytic anemia (AIHA) after 3 years of adalimumab treatment. …
- NAID 130005068301
- Protein A 結合羊赤血球を用いた, プラーク法による免疫グロブリン分泌細胞の検出 : 各種免疫不全疾患における成績
- 田中 晴樹,森田 耕輔,鶴和 美穂 [他],宋 大光,杉峰 啓憲,坂本 晴子,濱田 実保,葭井 操雄,森本 武志,住本 真一,山本 英彦,金岡 裕夫,新居 正甫,伊藤 容子,河村 ゆき江,友野 尚美
- 日赤醫學 = The Japanese Red Cross medical journal 57(2), 413-418, 2007-07-10
- NAID 10019734535
- Protein A 結合羊赤血球を用いた, プラーク法による免疫グロブリン分泌細胞の検出
- 田中 晴樹,森田 耕輔,鶴和 美穂 [他],宋 大光,杉峰 啓憲,坂本 晴子,濱田 実保,葭井 操雄,森本 武志,住本 真一,山本 英彦,金岡 裕夫,新居 正甫,伊藤 容子,河村 ゆき江
- 日赤醫學 = The Japanese Red Cross medical journal 57(2), 409-411, 2007-07-10
- NAID 10019734530
Related Links
- an assay that enumerates individual antibody-forming cells. Synonym(s): hemolytic plaque assay. Jer·ne plaque as·say (jĕr'nĕ plak as'ā). An assay that enumerates individual antibody-forming cells. Synonym(s): hemolytic plaque assay.
- Hemolytic Plaque Technique - definition. ... (From Illustrated Dictionary of Immunology, 3rd ed), hemolysis in gel goes here, Other names Jerne's Plaque Technique; Techniques, Hemolytic Plaque; Technique, Jerne's Plaque; Technique, ...
Related Pictures
★リンクテーブル★
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- 英
- hemolytic plaque
- 関
- 溶血プラーク
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- 英
- hemolytic plaque
- 関
- 溶血斑
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- 関
- atherosclerotic plaque
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- 関
- haemolysis、haemolytic、hemolysis、hemolyze