生殖結節
WordNet
- of or relating to the external sex organs; "genital herpes"; "venereal disease" (同)venereal
- a swelling that is the characteristic lesion of tuberculosis
PrepTutorEJDIC
- 生殖の,生殖器の
- 小塊茎,塊根 / 瘤状突起,結節
- 生殖器;(特に)外部生殖器
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/12/23 10:42:32」(JST)
[Wiki en表示]
Genital tubercle |
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Stages in the development of the external sexual organs in the male and female. |
Latin |
tuberculum phallicum; tuberculum genitale |
Gray's |
subject #252 1213 |
Precursor |
somatopleure[1] |
Gives rise to |
genital swelling, mons pubis, clitoris, penis |
Code |
TE E5.7.4.0.1.0.1 |
A genital tubercle or phallic tubercle is a body of tissue present in the development of the urinary and reproductive organs. It forms in the ventral, caudal region of mammalian embryos of both sexes, and eventually develops into a phallus. In the human fetus, the genital tubercle develops around week 4 of gestation, and by week 9 becomes recognizably either a clitoris or penis. This should not be confused with the sinus tubercle which is a proliferation of endoderm induced by paramesonephic ducts. Even after the phallus is developed, the term genital tubercle remains, but only as the terminal end of it,[2] which develops into either the glans penis or the glans clitoridis.
The genital tubercle is sensitive to dihydrotestosterone and rich in 5-alpha-reductase, so that the amount of fetal testosterone present after the second month is a major determinant of phallus size at birth.
See also[edit]
References[edit]
- ^ Netter, Frank H.; Cochard, Larry R. (2002). Netter's Atlas of human embryology. Teterboro, N.J: Icon Learning Systems. p. 159. ISBN 0-914168-99-1.
- ^ The University of North Carolina at Chapel Hill - Embryo images nr 024
External links[edit]
- Swiss embryology (from UL, UB, and UF) ugenital/genitexterne01
- Overview at mcgill.ca
Prenatal development/mammalian embryogenesis, Development of the urinary and reproductive organs (GA 11.1204, TE E5.6-7)
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Common urinary and
reproductive system |
- Mesoderm → Intermediate mesoderm
- Mesoderm → Lateral plate mesoderm ("LPM")
- Endoderm → Cloaca → Urogenital sinus ("US")
- Endoderm+Ectoderm → Cloacal membrane
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Urinary system
development |
- Nephrogenic cord → Kidney
- Nephrotome → Pronephros
- Mesonephros (Mesonephric tubules)
- WD → Ureteric bud + Metanephrogenic blastema
- US → Urinary bladder + Urethra + Primary urethral groove + Urachus
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Reproductive system
development |
Primarily internal |
- Gonadal ridge → Indifferent gonad → Gonadal cord (Cortical cords, Testis cords)
- Pronephric duct/Wolffian duct/mesonephric duct + Müllerian duct/paramesonephric ducts (Vaginal plate)
- US → Prostate or Skene's gland
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Primarily external |
- LPM → Genital tubercle → Labioscrotal swelling → Scrotum or Labia majora
- LPM → Genital tubercle → Primordial phallus → Penis or Clitoris
- Peritoneum → Processus vaginalis or Canal of Nuck
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Homologues |
- List of homologues of the human reproductive system
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noco/acba/cong/tumr, sysi/epon, urte
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proc/itvp, drug (G4B), blte, urte
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noco/cong/npls, sysi/epon
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proc/asst, drug (G1/G2B/G3CD)
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noco/cong/tumr, sysi/epon
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UpToDate Contents
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English Journal
- Targeted Resequencing of 29 Candidate Genes and Mouse Expression Studies Implicate ZIC3 and FOXF1 in Human VATER/VACTERL Association.
- Hilger AC1, Halbritter J2,3, Pennimpede T4,5, van der Ven A1,2, Sarma G6, Braun DA2, Porath JD2, Kohl S2, Hwang DY2, Dworschak GC1,2, Hermann BG4, Pavlova A7, El-Maarri O7,8, Nöthen MM1,9, Ludwig M10, Reutter H1,6, Hildebrandt F2,11.
- Human mutation.Hum Mutat.2015 Aug 21. doi: 10.1002/humu.22859. [Epub ahead of print]
- The VATER/VACTERL association describes the combination of congenital anomalies including vertebral defects, anorectal malformations, cardiac defects, tracheoesophageal fistula with or without esophageal atresia, renal malformations, and limb defects. As mutations in ciliary genes were observed in d
- PMID 26294094
- Expression Analysis of DGKK during External Genitalia Formation.
- Shen J1, Liu B1, Sinclair A1, Cunha G1, Baskin LS1, Choudhry S2.
- The Journal of urology.J Urol.2015 Jul 7. pii: S0022-5347(15)04317-7. doi: 10.1016/j.juro.2015.06.098. [Epub ahead of print]
- PURPOSE: Genetic variants in diacylglycerol kinase κ (DGKK) have been strongly associated with risk of hypospadias. We investigated the expression pattern of Dgkk during development of mouse external genitalia to better understand its function and mechanism in the etiology of hypospadias.MATERIALS
- PMID 26162297
- Tissue-specific roles of Fgfr2 in development of the external genitalia.
- Gredler ML1, Seifert AW1, Cohn MJ2.
- Development (Cambridge, England).Development.2015 Jun 15;142(12):2203-12. doi: 10.1242/dev.119891.
- Congenital anomalies frequently occur in organs that undergo tubulogenesis. Hypospadias is a urethral tube defect defined by mislocalized, oversized, or multiple openings of the penile urethra. Deletion of Fgfr2 or its ligand Fgf10 results in severe hypospadias in mice, in which the entire urethral
- PMID 26081573
Japanese Journal
- Ultrasonographic Fetal Sex Identification in Pregnant Sheep Derived from Natural Mating and Embryo Transfer
- DE FREITAS NETO Leopoldo Mayer,DOS SANTOS Maico Henrique Barbosa,DE AGUIAR FILHO Cristiano Rocha,DE ALMEIDA IRMAO Jose Monteiro,CALDAS Eduardo Luiz Cavalcanti,NEVES Jairo Pereira,LIMA Paulo Fernandes,DE OLIVEIRA Marcos Antonio Lemos
- The Journal of reproduction and development 56(3), 347-350, 2010-06-01
- … The objective of this study was to identify the migration period of the genital tubercle and the period of visualization of external genital structures in fetuses of the Dorper breed of sheep derived from natural mating and from fresh, frozen and vitrified embryo transfer. … Migration of the genital tubercle occurred earlier (P0.05) in NM (42.21 ± …
- NAID 10026434341
- Dosage-dependent hedgehog signals integrated with Wnt/β-catenin signaling regulate external genitalia formation as an appendicular program
- Shinichi Miyagawa,Anne Moon,Ryuma Haraguchi,Chie Inoue,Masayo Harada,Chiaki Nakahara,Kentaro Suzuki,Daisuke Matsumaru,Takehito Kaneko,Isao Matsuo,Lei Yang,Makoto M. Taketo,Taisen Iguchi,Sylvia M. Evans,Gen Yamada,ヤマダ ゲン,ハラグチ リュウマ,ハラダ マサヨ,スズキ ケンタロウ,山田 源,原口 竜摩,原田 理代,鈴木 堅太郎
- Development 136(23), 3969-3978, 2009-12-01
- … We demonstrate that a novel signaling cascade governs formation of theembryonic external genitalia [genital tubercle (GT)]. …
- NAID 120002469485
- Development of External Genitalia in Fetal and Neonatal Domestic Cats(Anatomy)
- INOMATA Tomo,ARIGA Makoto,SAKITA Katsuyasu,KASHIWAZAKI Naomi,ITO Junya,YOKOH Kiyofumi,ICHIKAWA Masahiko,NINOMIYA Hiroyoshi,INOUE Seiya
- The journal of veterinary medical science 71(2), 139-145, 2009-02-25
- … The female urogenital folds budded from each side of the genital tubercle and, gradually extended to the tip of the genital tubercle by the 6.8cm stage in crown-rump length. … Then, the well-developed urogenital folds ensheathed completely the genital tubercle to form the prepuce of clitoris and the labia, flanking the external opening of vagina as the folds of skin which were equivalent to the labia minora in humans. …
- NAID 110007109592
Related Links
- phallic tubercle this tubercle derived from the genital tubercle is the primordium of the penis or clitoris. Synonym(s): genital tubercle genital tubercle The embryonic structure that becomes the clitoris or the penis. See also: tubercle
- :a conical protuberance on the belly wall of an embryo between the attachment of the umbilical cord and the tail that develops into the penis in the male and the ... Seen and Heard What made you want to look up genital tubercle?
Related Pictures
★リンクテーブル★
[★]
- 英
- genital tubercle
- 関
- 外生殖器
- 英
- genital tubercle
[★]
ex.
- 関
- accessory sex organ、generative、genital organ、genital tract、genitalia、genitalium、reproduction、reproductive、reproductive organ、sexual organ
[★]
結節
- 関
- node、nodose、nodulate、tubercular、tuberosity