WordNet

of or relating to the stomach and intestines; "a gastrointestinal disorder" (同)GI
a line of small holes for tearing at a particular place
the act of punching a hole (especially a row of holes as for ease of separation)
a hole made in something; "a perforation of the eardrum"

PrepTutorEJDIC

胃腸の,胃腸に影響する
〈U〉穴をあけること / 〈C〉《しばしば複数形で》穴,ミシン目,切り取り線

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/08/18 10:34:36」(JST)

wiki en

Gastrointestinal perforation is a complete penetration of the wall of the stomach, small intestine or large bowel, resulting in intestinal contents flowing into the abdominal cavity. Perforation of the intestines results in the potential for bacterial contamination of the abdominal cavity (a condition known as peritonitis). Perforation of the stomach can lead to a chemical peritonitis due to leaked gastric acid. Perforation anywhere along the gastrointestinal tract is a surgical emergency.

Signs and symptoms[edit source | edit]

Sudden attack of pain in epigastrium to the right of midline in case of perforation of duodenal ulcer. In case of gastric ulcer the pain is in epigastrium. There is history of burning pain in epigastrium, flatulence and dyspepsia. History of drug intake without sufficient food intake may be present. In case of intestinal perforation pain starts from the site of perforation, visceral, and then spreads all over the abdomen. In any case there is board like rigidity of abdomen, tenderness, and rebound tenderness. After some time the abdomen becomes silent, heart sounds can be heard all over. Patient stops passing flatus and motion, abdomen is distended. Gastrointestinal perforation results in severe abdominal pain intensified by movement, nausea and vomiting. Later symptoms include fever and or chills.

Causes[edit source | edit]

Underlying causes include gastric ulcer, appendicitis, gastrointestinal cancer, diverticulitis, Inflammatory Bowel Disease, superior mesenteric artery syndrome, trauma, ascariasis. Typhoid fever, non-steroidal anti-inflammatory drugs, ingestion of corrosives may also be responsible.^{[citation needed]}

Diagnosis[edit source | edit]

On x-rays, free gas/air may be visible in the abdominal cavity. The perforation can often be visualised using computed tomography. White blood cells are often elevated. Visible signs can occasionally include a ridged abdomen on palpation.

Treatment[edit source | edit]

Treatment depends on the underlying cause. Surgical intervention is nearly always required in form of exploratory laparotomy and closure of perforation with peritoneal wash. Conservative treatment is indicated in case patient is nontoxic and clinically stable, these patients are to be treated with intravenous fluids, antibiotics, nasogastric aspiration and bowel rest. Consultation with a specialist is often needed.

External Links[edit source | edit]

Gastrointestinal perforation - MedlinePlus

UpToDate Contents

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1. 消化管穿孔の概要 overview of gastrointestinal tract perforation
2. 新生児の自然発生的な腸管穿孔 spontaneous intestinal perforation of the newborn
3. 成人患者における外傷性胃腸障害 traumatic gastrointestinal injury in the adult patient
4. 腸瘻の概要 overview of enteric fistulas
5. コンピュータ断層撮影コロノグラフィの概要 overview of computed tomographic colonography

English Journal

Patient preference and decision-making for initiating metastatic colorectal cancer medical treatment.

Fu AZ1,2, Graves KD3,4, Jensen RE3,4, Marshall JL4, Formoso M4, Potosky AL3,4.
Journal of cancer research and clinical oncology.J Cancer Res Clin Oncol.2016 Mar;142(3):699-706. doi: 10.1007/s00432-015-2073-4. Epub 2015 Nov 18.
PURPOSE: Some medical treatment for metastatic colorectal cancer (CRC) may have marginal survival benefit, but cause toxicities. The purpose of this study is to determine metastatic CRC patients' tradeoffs in making a decision to undergo new medical treatment.METHODS: We conducted a survey of patien
PMID 26577827

Ductal closure with intravenous paracetamol: a new approach to patent ductus arteriosus treatment.

Memisoglu A1, Alp Ünkar Z1, Cetiner N2, Akalın F2, Ozdemir H1, Bilgen HS1, Ozek E1.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.J Matern Fetal Neonatal Med.2016 Mar;29(6):987-90. doi: 10.3109/14767058.2015.1029912. Epub 2015 Apr 2.
OBJECTIVES: Indomethacin and ibuprofen are commonly used in the treatment of hemodynamically significant patent ductus arteriosus (hsPDA). These drugs are associated with serious adverse events, including gastrointestinal perforation, renal failure and bleeding. The role of paracetamol has been prop
PMID 25781500

Surgical Treatment of NEN of Small Bowel: A Retrospective Analysis.

Watzka FM1, Fottner C2, Miederer M3, Weber MM2, Schad A4, Lang H1, Musholt TJ5.
World journal of surgery.World J Surg.2016 Mar;40(3):749-58. doi: 10.1007/s00268-016-3432-2.
BACKGROUND: Neuroendocrine Neoplasms of the small intestine have been noticed more frequently over the past 35 years. They constitute about 25 % of all NENs and 29 % of all tumors of the small intestine. Due to the predominantly indolent nature and overall good prognosis, the benefit of surgical
PMID 26822157

Japanese Journal

消化管原発DLBCLにおける消化管穿孔

高橋直樹
血液内科 68(1), 85-91, 2014-01
NAID 40019971702

Pleomorphic Carcinoma Showing Rapid Growth, Multiple Metastases, and Intestinal Perforation

Koh Hidefumi,Chiyotani Atsushi,Tokuda Toshiki,Suzumura Hirofumi,Kamiishi Nobufumi,Takahashi Hidenori,Hirose Shigemichi
Annals of Thoracic and Cardiovascular Surgery, 2014
… Here we report a case of pleomorphic carcinoma with rapid growth, multiple metastases, and intestinal perforation. … He was diagnosed with gastrointestinal perforation, and he underwent surgery. …
NAID 130003396748

細径鉗子を用いた腹腔鏡・内視鏡合同手術（Laparoscopy Endoscopy Cooperative Surgery；LECS）を施行した横行結腸神経鞘腫の1例

向井俊貴,福長洋介,大野吏輝,友利賢太,池田篤志,永田淳,長嵜寿矢,秋吉高志,小西毅,藤本佳也,長山聡,上野雅資,千野晶子,為我井芳郎,五十嵐正広
日本大腸肛門病学会雑誌 67(3), 178-182, 2014
… ない切除を行う手技である．われわれは横行結腸粘膜下腫瘍に対して細径鉗子を用いたLECSにて横行結腸楔状切除を施行した．症例は63歳男性．下部消化管内視鏡検査で横行結腸に28mmの粘膜下腫瘍を認め，Gastrointestinal stromal tumor（以下GIST）が疑われ，腹腔鏡下手術の方針となった．手術は臍12mm，右下5mm，右上・左上下3mmの5ポート法で施行した．腹腔鏡下に大網および横行結腸間膜の直動脈を最低限処理し，腫瘍漿膜面 …
NAID 130003394582

Related Pictures

★リンクテーブル★

リンク元	「消化管穿孔」
関連記事	「gastrointestinal」「perforation」

「消化管穿孔」

Gastrointestinal perforation
	Classification and external resources
	; Free air under the right hemidiaphragm from a bowel perforated.
ICD-10	K63.1, S36.9
ICD-9	569.83, 863.9
DiseasesDB	34042
MedlinePlus	000235
eMedicine	med/2822

　　[★]

英: gastrointestinal perforation, perforation of digestive tract
関: 急性汎発性腹膜炎

治療

全身管理：(急性汎発性腹膜炎により循環血流減少性ショック、敗血症ショックをきたしていた場合)
手術：

(十二指腸潰瘍穿孔性腹膜炎)広汎胃切除術・穿孔部位閉鎖術・大網充填術、腹腔洗浄、腹腔ドレーン留置

禁忌

消化管内視鏡は穿孔を悪化させるめ。

「gastrointestinal」

　　[★]

adj.

胃腸の、胃腸管の、胃腸管系の
消化管の、消化器の、消化器系の

関: alimentary canal、alimentary system、alimentary tract、digestive organ、digestive system、digestive tract、gastrointestinal system、gastrointestinal tract、GI、GI tract、intestinal

「perforation」

　　[★]

n.

穿孔

関: bore、drill、perforate

匿名

検索

案内

案内

gastrointestinal perforation