- 関
- fetoprotein
WordNet
- any of several antigens that occur naturally in the fetus and sometimes in adults with cancer (同)foetoprotein
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
- of or relating to a fetus; "fetal development" (同)foetal
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- 蛋白(たんばく)質
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/02/07 02:43:12」(JST)
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Fetal proteins are high levels of proteins present during the fetal stage of development. Often related proteins assume similar roles after birth or in the embryo, in which case the fetal varieties are called fetal isoforms. Sometimes, the genes coding fetal isoforms occur adjacent to their adult homologues in the genome, and in those cases a locus control region often coordinates the transition from fetal to adult forms. In other cases fetal isoforms can be produced by alternate splicing using fetal exons to produce proteins that differ in only a portion of their amino acid sequence. In some situations the continuing expression of fetal forms can reveal the presence of a disease condition or serve as a treatment for diseases such as sickle cell anemia. Some well known examples include:
- Alpha-fetoprotein, the predominant serum protein of the fetus which gives way to albumin in the adult.
- Fetal hemoglobin, the fetal version of hemoglobin.
- Fetal Troponin T and Troponin I isoforms.
UpToDate Contents
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- 1. 肝細胞癌の臨床的特徴と診断clinical features and diagnosis of hepatocellular carcinoma [show details]
…in combination with the serum AFP have been evaluated for diagnosis in patients with HCC including des-gamma-carboxy prothrombin , lens culinaris agglutinin-reactive AFP (AFP-L3) , and glypican-3 (a cell-surface …
- 2. 神経管閉鎖障害:危険因子、出生前診断、妊娠中の管理open neural tube defects risk factors prenatal screening and diagnosis and pregnancy management [show details]
…function as an intravascular transport protein. Alpha-fetoprotein can be measured in maternal serum (MSAFP), amniotic fluid, and fetal plasma. The MSAFP concentration is much lower than that in amniotic …
- 3. 精巣胚細胞腫瘍における血清腫瘍マーカーserum tumor markers in testicular germ cell tumors [show details]
…in serum AFP (10.4 to 16 ng/mL) . Higher serum AFP concentrations are considered diagnostic of a nonseminomatous component of the tumor or hepatic metastases . If the presence of elevated serum AFP is …
- 4. 肝細胞癌における病期分類および予後因子staging and prognostic factors in hepatocellular carcinoma [show details]
…accepted into practice. The serum alpha-fetoprotein (AFP) level at presentation correlates with tumor size and extent . The relationship between tumor growth and the rise in serum AFP was evaluated in a report …
- 5. ダウン症の母体血清スクリーニングに関する臨床検査の問題laboratory issues related to maternal serum screening for down syndrome [show details]
…early second trimester (optimally at 15 to 18 weeks of gestation). Four markers are measured: Alpha fetoprotein (AFP) Unconjugated estriol (uE3) Total/intact human chorionic gonadotropin (hCG) or the free …
English Journal
- Adipocytes as lipid sensors of oleic acid transport through a functional Caco-2/HT29-MTX intestinal barrier.
- Berger E, Géloën A.
- Adipocyte. 2019 Dec;8(1)83-97.
- Adipose tissue function in the regulation of lipemia is highly dependent on intestinal absorption of nutrients. Therefore the aim of the present study was the development and validation of an in vitro multiculture model allowing to measure intestinal absorption using adipocytes as lipid sensors. We
- PMID 30905315
- Protein kinase C Inhibitors selectively modulate dynamics of cell adhesion molecules and cell death in human colon cancer cells.
- Dükel M, Tavsan Z, Erdogan D, Erkan Gök D, Ayar Kayali H.
- Cell adhesion & migration. 2019 Dec;13(1)83-97.
- During development of colon cancer, Protein Kinase Cs (PKCs) are involved in regulation of many genes controlling several cellular mechanisms. Here, we examined the changes in cell adhesion molecules and PKCs for colorectal cancer progression. We identified that PKCs affected expression of EpCAM, cl
- PMID 30289336
- Early onset of renal oxidative stress in small for gestational age newborn pigs.
- Soni H, Yakimkova T, Matthews AT, Amartey PK, Read RW, Buddington RK, Adebiyi A.
- Redox report : communications in free radical research. 2019 Dec;24(1)10-16.
- Oxidative stress, a common feature in cardiovascular and renal disease is associated with the causes and consequences of fetal growth restriction. Hence, renal redox status is likely an early determinant of morbidity in small-for-gestational-age (SGA) infants. In this study, we examined renal oxidat
- PMID 30907266
Japanese Journal
- Eosinophil Cationic Protein Shows Survival Effect on H9c2 Cardiac Myoblast Cells with Enhanced Phosphorylation of ERK and Akt/GSK-3β under Oxidative Stress
- Indium tin oxide based chip for optical and electrochemical characterization of protein–cell interaction
- ISP-11-2 Maternal serum pregnancy-associated plasma protein-A (PAPP-A) as a predictor of severe preeclampsia(Group 11 Perinatology 1,IS Poster,International Session)
Related Links
- Fetal Metabolism As a fetus receives nutrients from the umbilical cord until delivery, it is obvious that a newborn premature should receive nutrients as well. Human fetal protein and amino acid metabolism can be studied in vivo
- ウシ胎児血清(FBS:Fetal Bovine Serum) | バイオロジカルインダストリーズ社のウシ胎児血清(FBS:Fetal bovine serum)は、品質マネジメントシステムISO9001:2008およびISO13485:2003に準拠して製造された、高品質なUSDAグレード
- 【製品の品質保証】 全ての血清は管理された製造工程で製造され、適正な品質試験を実施後出荷しております。 試験内容、規格は製品ごとに異なります。詳細は弊社までお問い合わせください。 各製品のロット毎に、原産国を含めた全ての試験結果を記載した「試験成績書」をご提供すること ...
★リンクテーブル★
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フェトプロテイン、胎児タンパク質、胎児蛋白
- 関
- AFP、alpha-fetoprotein、fetal protein、fetuin
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- 英
- fetal protein、fetoprotein
- 関
- 胎児蛋白、フェトプロテイン
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- 胎生期の、胎性の、(人間)胎児の、胎児性の、(動物)胎仔の、胎仔型の
- 関
- embryo、embryonal、embryonic、embryonic day、embryonic form、embryonic stage、fetal stage、feto、fetus、foetal、foetus