WordNet
- come on stage
- to come or go into; "the boat entered an area of shallow marshes" (同)come_in, get_into, get_in, go_into, go in, move into
- become a participant; be involved in; "enter a race"; "enter an agreement"; "enter a drug treatment program"; "enter negotiations" (同)participate
- of or relating to cats; "feline fur"
- any of various lithe-bodied roundheaded fissiped mammals, many with retractile claws (同)felid
- of or relating to the enteron (同)enteral
PrepTutorEJDIC
- …‘に'『入る』,入り込む / 〈弾丸などが〉…‘を'突き通す,‘に'入り込む(penetrate) / …‘の'『一員となる』,‘に'入る;…‘に'参加する / (…に)〈人〉‘を'入学させる;(競争などに)〈人・動物など〉‘を'参加させる《+『名』+『in』(『for』)+『名』》 / (…に)…‘を'記入する,登録する《+『名』+『in』(『into, on』)+『名』》 / 〈新しい生活・局面など〉‘に'入る / 〈異議など〉‘を'正式に申し出る / 『入る』 / 登場する
- ネコ科(属)の,猫の / 猫のような / ネコ科の動物(猫・トラ・ヒョウなど)
UpToDate Contents
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- 1. コロナウイルス coronaviruses
- 2. 成人におけるウイルス性胃腸炎の疫学 epidemiology of viral gastroenteritis in adults
- 3. 小児におけるウイルス性胃腸炎の疫学、病因、臨床症状および診断 epidemiology pathogenesis clinical presentation and diagnosis of viral gastroenteritis in children
- 4. 新生児における院内ウイルス感染症 nosocomial viral infections in the neonate
- 5. 幼児および小児における細気管支炎：臨床的特徴および診断 bronchiolitis in infants and children clinical features and diagnosis
English Journal
- ORF7-encoded accessory protein 7a of feline infectious peritonitis virus as a counteragent against IFN-α-induced antiviral response.
- Dedeurwaerder A, Olyslaegers DA, Desmarets LM, Roukaerts ID, Theuns S, Nauwynck HJ.Author information Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium.AbstractThe type I IFN-mediated immune response is the first line of antiviral defence. Coronaviruses, like many other viruses, have evolved mechanisms to evade this innate response, ensuring their survival. Several coronavirus accessory genes play a central role in these pathways, but for feline coronaviruses this has never to our knowledge been studied. As it has been demonstrated previously that ORF7 is essential for efficient replication in vitro and virulence in vivo of feline infectious peritonitis virus (FIPV), the role of this ORF in the evasion of the IFN-α antiviral response was investigated. Deletion of ORF7 from FIPV strain 79-1146 (FIPV-Δ7) rendered the virus more susceptible to IFN-α treatment. Given that ORF7 encodes two proteins, 7a and 7b, it was further explored which of these proteins is active in this mechanism. Providing 7a protein in trans rescued the mutant FIPV-Δ7 from IFN sensitivity, which was not achieved by addition of 7b protein. Nevertheless, addition of protein 7a to FIPV-Δ3Δ7, a FIPV mutant deleted in both ORF3 and ORF7, could no longer increase the replication capacity of this mutant in the presence of IFN. These results indicate that FIPV 7a protein is a type I IFN antagonist and protects the virus from the antiviral state induced by IFN, but it needs the presence of ORF3-encoded proteins to exert its antagonistic function.
- The Journal of general virology.J Gen Virol.2014 Feb;95(Pt 2):393-402. doi: 10.1099/vir.0.058743-0. Epub 2013 Nov 4.
- The type I IFN-mediated immune response is the first line of antiviral defence. Coronaviruses, like many other viruses, have evolved mechanisms to evade this innate response, ensuring their survival. Several coronavirus accessory genes play a central role in these pathways, but for feline coronaviru
- PMID 24189622
- Use of recombinant nucleocapsid proteins for serological diagnosis offeline coronavirus infection by three immunochromatographic tests.
- Takano T, Ishihara Y, Matsuoka M, Yokota S, Matsuoka-Kobayashi Y, Doki T, Hohdatsu T.AbstractThree types of immunochromatographic assays (ICAs) were designed to detect anti-feline coronavirus (FCoV) antibodies. Recombinant FCoV nucleocapsid protein (rNP) was used as a conjugate or test line in all 3 ICA kits (CJIgG/TNP, CJNP/TNP, and CJNP/TPA). All three ICA kits were capable of detecting anti-FCoV antibodies; however, non-specific positive reactions of anti-FCoV antibody-negative plasma samples with the test line were observed in 2 ICA kits (CJIgG/TNP and CJNP/TNP), in which rNP was used as the test line. On the other hand, the specific detection of anti-FCoV antibodies was possible in all plasma, serum, whole blood, and ascitic fluid samples using the ICA kit with protein A blotted as the test line (CJNP/TPA). In addition, the specificity and sensitivity of ICA (CJNP/TPA) were equivalent to those of the reference ELISA. The development of simple antibody test methods using the principle of ICA (CJNP/TPA) for other coronavirus and feline viral infections is expected in the future.
- Journal of virological methods.J Virol Methods.2014 Feb;196:1-6.
- Three types of immunochromatographic assays (ICAs) were designed to detect anti-feline coronavirus (FCoV) antibodies. Recombinant FCoV nucleocapsid protein (rNP) was used as a conjugate or test line in all 3 ICA kits (CJIgG/TNP, CJNP/TNP, and CJNP/TPA). All three ICA kits were capable of detecting a
- PMID 24516876
- Evaluation of protective efficacy of the synthetic peptide vaccine containing the T helper 1 epitope with CpG oligodeoxynucleotide against feline infectious peritonitis virus infection in cats.
- Takano T, Tomizawa K, Morioka H, Doki T, Hohdatsu T.Author information Laboratory of Veterinary Infectious Disease, School of Veterinary Medicine, Kitasato University, Towada, Japan.AbstractBACKGROUND: Feline infectious peritonitis (FIP) is a feline coronavirus-induced fatal disease in domestic and wild cats. Cellular immunity is considered to play an important role in the prevention of FIP. Thus, induction of the cellular immune response is essential in vaccines against FIP virus (FIPV) infection.
- Antiviral therapy.Antivir Ther.2014 Jan 23. doi: 10.3851/IMP2735. [Epub ahead of print]
- BACKGROUND: Feline infectious peritonitis (FIP) is a feline coronavirus-induced fatal disease in domestic and wild cats. Cellular immunity is considered to play an important role in the prevention of FIP. Thus, induction of the cellular immune response is essential in vaccines against FIP virus (FIP
- PMID 24458025
Japanese Journal
- ネコマクロファージおよびヒト単球U937細胞でのネコ伝染性腹膜炎ウイルスのネココロナウイルス実験感染および自然感染ネコ血清による感染増強作用
- 宝達 勉,山田 三佳,富永 律子,牧野 香,木田 浩司,小山 弘之
- The journal of veterinary medical science 60(1), 49-55, 1998-01-25
- ネコ伝染性腹膜炎ウイルス (FIPV) II型79-1146株のネコ肺胞マクロファージおよびヒト単球U937細胞への感染は, ホモのウイルスである79-1146株感染血清でのみ増強され, FIPV I型のKU-2株あるいはUCD-1株感染血清では増強されなかった. FIP発症ネコおよびネココロナウイルス (FCoV) 自然感染血清を使用した実験でも, II型のFIPVあるいはII型のネコ腸コロナウ …
- NAID 110003918377
- Antibody-Dependent Enhancement of Feline Infectious Peritonitis Virus Infection in Feline Alveolar Macrophages and Human Monocyte Cell Line U937 by Serum of Cats Experimentally or Naturally Infected with Feline Coronavirus
- HOHDATSU Tsutomu,YAMADA Mika,TOMINAGA Ritsuko,MAKINO Kaori,KIDA Kouji,KOYAMA Hiroyuki
- Journal of Veterinary Medical Science 60(1), 49-55, 1998
- … Infection of the type II feline infectious peritonitis virus (FIPV) strain 79-1146 to primary feline alveolar macrophages and human monocyte cell line U937 was enhanced by the sera of cats experimentally infected with the 79-1146 strain, but not those of cats infected with KU-2 or UCD-1 strain of type I FIPV. …
- NAID 130000437997
Related Links
- Feline enteric coronavirus (FECV) is an enveloped, single-stranded RNA virus that is highly prevalent in domestic cat populations worldwide. Infection is often subclinical or characterized by transient, mild GI illness in kittens. Mutation ...
- feline enteric coronavirus a cause of mild enteritis in kittens. It is closely related to feline infectious peritonitis virus. coronavirus Virology The single genus of the family Coronaviridae, which have a corona or halo-like appearance by . ...
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★リンクテーブル★
| リンク元 | 「FIPV」「FECV」「feline coronavirus」「ネコ腸コロナウイルス」「feline infectious peritonitis virus」 |
| 関連記事 | 「coronavirus」「feline」「enter」「enteric」 |
「FIPV」
「FECV」
「ネコ腸コロナウイルス」
「feline infectious peritonitis virus」
「feline」
- adj.
- ネコの
「enter」
- v.
- 入る、進入する
「enteric」
- adj.
- 腸の。腸溶性の
- 同
- enteral