WordNet

(physical chemistry) a sample of matter in which substances in different phases are in equilibrium; "in a static system oil cannot be replaced by water on a surface"; "a system generating hydrogen peroxide"
instrumentality that combines interrelated interacting artifacts designed to work as a coherent entity; "he bought a new stereo system"; "the system consists of a motor and a small computer"
a group of independent but interrelated elements comprising a unified whole; "a vast system of production and distribution and consumption keep the country going" (同)scheme
a complex of methods or rules governing behavior; "they have to operate under a system they oppose"; "that language has a complex system for indicating gender" (同)system of rules
a group of physiologically or anatomically related organs or parts; "the body has a system of organs for digestion"
a procedure or process for obtaining an objective; "they had to devise a system that did not depend on cooperation"
the living body considered as made up of interdependent components forming a unified whole; "exercise helped him get the alcohol out of his system"
use recreational drugs (同)do drugs
administer a drug to; "They drugged the kidnapped tourist" (同)dose
a substance that is used as a medicine or narcotic

PrepTutorEJDIC

〈C〉(関連した部分から成る)『体系』,系統,組織[網],装置 / 〈C〉(教育・政治などの)『制度』,機構;《the~》体制 / 〈C〉(思想・学問などの)『体系』,学説 / 〈C〉(…の)『方法』,方式,やり方《+of doing》 / 〈U〉正しい方針(筋道,順序) / 〈U〉《the~》(身体の)組織,系統 / 〈U〉《the~,one's~》身体,全身
『薬』,薬品,薬剤 / 『麻薬』,麻酔剤 / 〈人〉‘に'薬(特に麻酔剤)を与える / 〈飲食物〉‘に'(麻酔薬・毒薬などの)薬を混ぜる

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Entrapment of human flavin-containing monooxygenase 3 in the presence of gold nanoparticles: TEM, FTIR and electrocatalysis.

Castrignanò S, Sadeghi SJ, Gilardi G.SourceDepartment of Life Sciences and Systems Biology, University of Torino, via Accademia Albertina, 13, 10123 Torino, Italy.
Biochimica et biophysica acta.Biochim Biophys Acta.2012 Oct 1. pii: S0304-4165(12)00272-3. doi: 10.1016/j.bbagen.2012.09.017. [Epub ahead of print]
BACKGROUND: Nanosized particles of gold are widely used as advanced materials for enzyme catalysis investigations. In some bioanalytical methods these nanoparticles can be exploited to increase the sensitivity by enhancing electron transfer to the biological component i.e. redox enzymes such as drug
PMID 23036595

Opdam FL, Gelderblom H, Guchelaar HJ.SourceDepartment of Clinical Pharmacy, University Medical Center, Leiden, The Netherlands. f.l.opdam@lumc.nl
Cancer treatment reviews.Cancer Treat Rev.2012 Oct;38(6):715-25. Epub 2012 Jan 4.
Efficacy and toxicity of anticancer agents are highly variable between patients and variation in drug disposition is thought to be an important determinant. Genetics, physiology, and environment all are underlying factors contributing to this variation. Phenotyping drug metabolizing enzymes and drug
PMID 22226243

A Simple Liquid Chromatography-Tandem Mass Spectrometry Method for Determination of Plasma Fentanyl Concentration in Rats and Patients with Cancer Pain

Hisada Tatsuya,Katoh Miki,Hitoshi Kotaro,Kondo Yuya,Fujioka Miho,Toyama Yukio,Ieda Hideaki,Gocho Saori,Nadai Masayuki
Biological and Pharmaceutical Bulletin, 2012
… Since fentanyl is predominantly metabolized by the drug-metabolizing enzyme cytochrome P450 (CYP) 3A4 in the liver, its concentration may vary in cases of physiologically reduced CYP3A4 activity in the liver (liver disease and aging) or on co-administration of drugs. …
NAID 130002480766

Expression of albumin and cytochrome P450 enzymes in HepG2 cells cultured with a nanotechnology-based culture plate with microfabricated scaffold

Nakamura Kazuaki,Kato Natsuko,Aizawa Kazuko [他],MIZUTANI Reiko,YAMAUCHI Junji,TANOUE Akito
Journal of toxicological sciences 36(5), 625-633, 2011-10-01
… These results suggest that the use of an NCP enhances the hepatocyte-specific functions of HepG2 cells, such as drug-metabolizing enzyme expression, making the NCP/HepG2 system a useful tool for evaluating drug metabolism in vitro. …
NAID 10029481453

Evaluation of drug toxicity with hepatocytes cultured in a micro-space cell culture system(CELL AND TISSUE ENGINEERING)

Nakamura Kazuaki,Mizutani Reiko,Sanbe Atsushi [他],Enosawa Shin,Kasahara Mureo,Nakagawa Atsuko,Ejiri Yoko,Murayama Norie,Miyamoto Yuki,Torii Tomohiro,Kusakawa Shinji,Yamauchi Junji,Fukuda Motohiro,Yamazaki Hiroshi,Tanoue Akito
Journal of bioscience and bioengineering 111(1), 78-84, 2011-01
… A micro-space cell culture system was recently developed in which cells such as hepatocytes can be cultured and formed into a multicellular three-dimensional (3D) architecture. … In this study, we assessed the performance of HepG2 cells cultured in this micro-space cell culture system in a drug toxicity test, and evaluated the effects of micro-space culture on their hepatocyte-specific functions. …
NAID 110008440354