サイクリンD1遺伝子
WordNet
- (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
- the 4th letter of the Roman alphabet (同)d
- informal term for information; "give me the gen on your new line of computers"
PrepTutorEJDIC
- 遺伝子
- deuteriumの化学記号
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Construction of the tissue engineering seed cell (HaCaT-EGF) and analysis of its biological characteristics.
- Tao K, Bai XZ, Zhang ZF, Shi JH, Hu XL, Tang CW, Hu DH, Han JT.SourceBurn Center of PLA, Xijing Hospital, the Fourth Military Medical University, Xi'an 710032, P.R. China.
- Asian Pacific journal of tropical medicine.Asian Pac J Trop Med.2013 Nov;6(11):893-896. doi: 10.1016/S1995-7645(13)60159-5.
- OBJECTIVE: To construct the tissue engineering seed cell (HaCaT cell line) with stable expression of the human epidermal growth factor (EGF), and analyze the changes of its biological characteristics.METHODS: PCDNA3.1-EGF eukaryotic expression vector was transferred into HaCaT cell, and G418 was uti
- PMID 24083586
- Oxidative stress-induced cyclin D1 depletion and its role in cell cycle processing.
- Pyo CW, Choi JH, Oh SM, Choi SY.SourceDepartment of Life Sciences, School of Life Sciences and Biotechnology, Korea University, Seoul 136-701, Korea.
- Biochimica et biophysica acta.Biochim Biophys Acta.2013 Nov;1830(11):5316-25. doi: 10.1016/j.bbagen.2013.07.030. Epub 2013 Aug 3.
- BACKGROUND: Cyclin D1 is immediately down-regulated in response to reactive oxygen species (ROS) and implicated in the induction of cell cycle arrest in G2 phase by an unknown mechanism. Either treatment with a protease inhibitor alone or expression of protease-resistant cyclin D1 T286A resulted in
- PMID 23920145
- Dolastatin, along with Celecoxib, stimulates apoptosis by a mechanism involving oxidative stress, membrane potential change and PI3-K/AKT pathway down regulation.
- Piplani H, Rana C, Vaish V, Vaiphei K, Sanyal SN.SourceDepartment of Biophysics, Panjab University, Chandigarh 160014, India.
- Biochimica et biophysica acta.Biochim Biophys Acta.2013 Nov;1830(11):5142-56. doi: 10.1016/j.bbagen.2013.07.011. Epub 2013 Jul 18.
- BACKGROUND: Phosphoinositide 3-kinase (PI3-K) is an important regulator of oncogenesis and apoptosis in various types of cancers including colon cancer. A combinatorial strategy of using Cyclooxygenase-2 inhibitor, Celecoxib and Dolastatin, a linear peptide from marine mollusks of Indian Ocean origi
- PMID 23872169
Japanese Journal
- Molecular Targeting Therapy Against Promyelocytic Leukemia Protein Using Arsenic Acids in Experimental Intracranial Medulloblastoma
- GU Chunyu,YOKOTA Naoki,GAO Yun,AMANO Shinji,KOIZUMI Shinichiro,TOKUYAMA Tsutomu,NAMBA Hiroki
- Neurologia medico-chirurgica = 神経外科 52(2), 62-67, 2012-02-15
- … Our previous study using human Daoy medulloblastoma cells showed that the promyelocytic leukemia (PML) gene was significantly upregulated (2.5-fold) in cells positive to prominin-1 antigen (CD133), a possible marker for cancer initiating cells. … PML and CCND1 (cyclin D1) protein expression of Daoy medulloblastoma cells was downregulated by As2O3 treatment. …
- NAID 10030127244
- Reversion-inducing cysteine-rich protein with Kazal motifs interferes with epidermal growth factor receptor signaling
- Kitajima Shunsuke,Miki T.,Takegami Yujiro,Kido Y.,Noda M.,Hara Eiji,Shamma Awad,Takahashi Chiaki
- Oncogene 30(6), 737-750, 2011-02-10
- … The reversion-inducing cysteine-rich protein with Kazal motifs (RECK) gene had been isolated as an antagonist to RAS signaling; … Within 2 days of RECK depletion, we observed a transient increase in protein kinase B (AKT) and extracellular signal-regulated kinase (ERK) phosphorylation associated with an upregulated expression of cyclin D1, p19Arf, Trp53, p21Cdkn1a and Sprouty 2. …
- NAID 120002907445
Related Links
- G1/S-specific cyclin-D1 is a protein that in humans is encoded by the CCND1 gene. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein ...
- cyclin D1 (Previous name: cyclin D1 (PRAD1: parathyroid adenomatosis 1) ) CCND1: Approved symbol from the HUGO Gene Nomenclature Committee ( HGNC) database (Previous symbols: BCL1, D11S287E, PRAD1) ...
Related Pictures
![Cyclin D as a therapeutic target in cancer](https://1mg.info/0/b/y/2737.jpg)
![temporally downstream of cyclin D1 (41](https://1mg.info/0/b/y/2738.jpg)
![Addgene - cyclin D1-HA-pBabe-Hygro Plasmid](https://1mg.info/0/b/y/2739.jpg)
![figure 5 cyclin d1 gene expression](https://1mg.info/0/b/y/2740.jpg)
![Figure 1 : Are all cancer genes equal](https://1mg.info/0/b/y/2741.jpg)
★リンクテーブル★
[★]