クリティカルパス、クリティカルパスウェイ
- 関
- clinical path
WordNet
- of or involving or characteristic of critics or criticism; "critical acclaim"
- forming or having the nature of a turning point or crisis; "a critical point in the campaign"; "the critical test" (同)decisive
- urgently needed; absolutely necessary; "a critical element of the plan"; "critical medical supplies"; "vital for a healthy society"; "of vital interest" (同)vital
- at or of a point at which a property or phenomenon suffers an abrupt change especially having enough mass to sustain a chain reaction; "a critical temperature of water is 100 degrees C--its boiling point at standard atmospheric pressure"; "critical mass"; "go critical"
- being in or verging on a state of crisis or emergency; "a critical shortage of food"; "a critical illness"; "an illness at the critical stage"
- characterized by careful evaluation and judgment; "a critical reading"; "a critical dissertation"; "a critical analysis of Melvilles writings"
- marked by a tendency to find and call attention to errors and flaws; "a critical attitude"
- a person who is professionally engaged in the analysis and interpretation of works of art
- anyone who expresses a reasoned judgment of something
- someone who frequently finds fault or makes harsh and unfair judgments
- a trodden path (同)footpath
PrepTutorEJDIC
- 『評論の』,批評の / 批判的な,物を見る眼のある / 『酷評的な』,あら捜しの,手きびしい / 『危機の』,危急の;(病気が)危篤の / 臨界の(温度・圧力などにより物質が急速にその状態を変える境),臨界点における
- (特に文学・美術・音楽の)『評論家』,『批評家』 / あら捜しをする人,酷評する人
- 道,小道(path)
UpToDate Contents
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- 1. 止血の概要 overview of hemostasis
- 2. 骨格の正常な発達および骨形成ならびに骨吸収の調節 normal skeletal development and regulation of bone formation and resorption
- 3. 視神経膠腫 optic pathway glioma
- 4. 重症疾患に関連する神経筋脱力 neuromuscular weakness related to critical illness
- 5. 補体系の遺伝性疾患 inherited disorders of the complement system
English Journal
- A holistic view of cancer bioenergetics: mitochondrial function and respiration play fundamental roles in the development and progression of diverse tumors.
- Alam MM1, Lal S2, FitzGerald KE3, Zhang L4.
- Clinical and translational medicine.Clin Transl Med.2016 Dec;5(1):3. doi: 10.1186/s40169-016-0082-9. Epub 2016 Jan 26.
- Since Otto Warburg made the first observation that tumor cells exhibit altered metabolism and bioenergetics in the 1920s, many scientists have tried to further the understanding of tumor bioenergetics. Particularly, in the past decade, the application of the state-of the-art metabolomics and genomic
- PMID 26812134
- Cost of surviving sepsis: a novel model of recovery from sepsis in Drosophila melanogaster.
- Kaynar AM1, Bakalov V2, Laverde SM3, Cambriel AI4, Lee BH5, Towheed A6,7, Gregory AD3, Webb SA8, Palladino MJ6, Bozza FA9, Shapiro SD3, Angus DC2.
- Intensive care medicine experimental.Intensive Care Med Exp.2016 Dec;4(1):4. doi: 10.1186/s40635-016-0075-4. Epub 2016 Jan 21.
- BACKGROUND: Multiple organ failure, wasting, increased morbidity, and mortality following acute illness complicates the health span of patients surviving sepsis. Persistent inflammation has been implicated, and it is proposed that insulin signaling contributes to persistent inflammatory signaling du
- PMID 26791145
- Activation of ERK pathway is required for 15-HETE-induced angiogenesis in human umbilical vascular endothelial cells.
- Wang S1, Cao W1, Xing H1, Chen YL2, Li Q1, Shen T1, Jiang C1,3, Zhu D1,2.
- Journal of receptor and signal transduction research.J Recept Signal Transduct Res.2016 Jun;36(3):225-32. doi: 10.3109/10799893.2015.1077865. Epub 2015 Oct 13.
- Angiogenesis plays a critical role in the progression of cardiovascular disease, retinal ischemia, or tumorigenesis. The imbalance of endothelial cell proliferation and apoptosis disturbs the establishment of the vasculogenesis, which is affected by several arachidonic acid metabolites. 15-Hydroxyei
- PMID 26460784
Japanese Journal
- A Novel Inhibitor of I-KappaB Kinase Beta Ameliorates Experimental Arthritis through Downregulation of Proinflammatory Cytokines in Arthritic Joints
- Tanaka Shinji,Toki Tadashi,Yokoyama Mika,Shimizu Hiroki,Yamasaki Tomonori,Yoneda Yoshiyuki,Muro Fumihito,Yasukochi Takanori,Iimura Shin,Morishita Kaoru
- Biological and Pharmaceutical Bulletin 37(1), 87-95, 2014
- … Inhibitor of kappaB (IκB) kinase beta (IKKβ) plays a critical role in nuclear factor-kappaB (NF-κB) activation and production of proinflammatory cytokines in various inflammatory diseases including rheumatoid arthritis. … The cellular analyses revealed that Compound D selectively blocked NF-κB promoter activity among major cellular signaling pathways, such as the activator protein-1 pathway, consistent with inhibition of the NF-κB signaling pathway including phosphorylation of IκBα. …
- NAID 130003382106
- Astragaloside IV Inhibits Doxorubicin-Induced Cardiomyocyte Apoptosis Mediated by Mitochondrial Apoptotic Pathway via Activating the PI3K/Akt Pathway
- Jia Yuanyuan,Zuo Daiying,Li Zengqiang,Liu Hanmo,Dai Zhengning,Cai Jiayi,Pang Lili,Wu Yingliang
- Chemical and Pharmaceutical Bulletin 62(1), 45-53, 2014
- … Mitochondria-mediated cardiomyocyte apoptosis plays a critical role in DOX-induced cardiotoxicity (DIC). … Western blot analysis manifested that AS-IV significantly inhibited the activation of mitochondrial apoptotic pathway (MAP) via inducing the phosphorylation of Akt and Bad. … Taken together, our findings indicate that AS-IV ameliorates DIC, and this beneficial effect appears to be dependent on the activation of the PI3K/Akt pathway. …
- NAID 130003381803
- 慢性腎臓病地域連携クリティカルパスを用いた診療システムの2年間のアウトカムとバリアンスに関する検討
Related Links
- Critical Pathways Change is required. There is a process of change, just as there is a process of manufacturing, or for growing wheat. W. Edwards Deming Change seems to be the prevailing experience in health care settings these ...
- Evaluate Medical Evidence and External Practices After key rate-limiting steps have been identified, the critical pathway team must evaluate the literature to identify evidence of best practices. For most rate-limiting ...
★リンクテーブル★
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- 英
- critical pathway
- 関
- クリニカルパス、クリティカルパスウェイ
- クリティカルパスとは、良質な医療を効率的、かつ安全、適正に提供するための手段として開発された診療計画表。
- もともとは、1950年代に米国の工業界で導入されはじめ、 1980年代に米国の医療界で使われ出した後、 1990年代に日本の医療機関においても一部導入された考え方。診療の標準化、根拠に基づく医療の実施(EBM)、インフォームドコンセントの充実、業務の改善、チーム医療の向上などの効果が期待されている。
参考
- http://www.mhlw.go.jp/stf/shingi/2r9852000000uta3-att/2r9852000000uthc.pdf
[★]
- 英
- critical pathway
- 関
- クリティカルパス
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クリニカルパス
- 関
- critical pathway
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地域連携クリティカルパス
[★]
- 関
- conclusive、conclusively、critically、criticise、criticism、criticize、critique、crucial、crucially、decisive、definitive、definitively、final
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- 関
- route