コンパウンドQ
- 関
- trichosanthin
WordNet
- create by mixing or combining
- (chemistry) a substance formed by chemical union of two or more elements or ingredients in definite proportion by weight (同)chemical_compound
- put or add together; "combine resources" (同)combine
- an enclosure of residences and other building (especially in the Orient)
- a whole formed by a union of two or more elements or parts
- combine so as to form a whole; mix; "compound the ingredients" (同)combine
- calculate principal and interest
- composed of more than one part; "compound leaves are composed of several lobes; "compound flower heads"
- consisting of two or more substances or ingredients or elements or parts; "soap is a compound substance"; "housetop is a compound word"; "a blackberry is a compound fruit"
- the 17th letter of the Roman alphabet (同)q
- the last imperial dynasty of China (from 1644 to 1912) which was overthrown by revolutionaries; during the Qing dynasty China was ruled by the Manchu (同)Qing dynasty, Ch''ing, Ch''ing dynasty, Manchu, Manchu dynasty
- combined into or constituting a chemical compound
PrepTutorEJDIC
- (…になるように)〈要素・成分など〉'を'混ぜ合わせる《+『名』+『into』+『名』》;(…から)〈薬など〉'を'調合する,混ぜ合わせて作る《+『名』+『from』(『of』)+『名』》 / 《しばしば受動態で》〈めんどうな事・損害など〉'を'もっとひどくする / 〈利子〉'を'複利で計算する / (…と)話し合いをつける,妥協する《+『with』+『名』》 / 複合の,合成の / 『合成物』,混合物,調合物;化合物 / 複合語,合成語(classroom, heart-to-heartなどをいう)
- (異民族の家屋・商館などがある)囲み地区,構内
- (チェスの)queen
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/05/24 19:45:48」(JST)
[Wiki en表示]
Trichosanthin is a ribosome-inactivating protein.[1][2]
It is derived from Trichosanthes kirilowii.[3]
It is also an abortifacient.[4]
References
- ^ Too PH, Ma MK, Mak AN, et al. (February 2009). "The C-terminal fragment of the ribosomal P protein complexed to trichosanthin reveals the interaction between the ribosome-inactivating protein and the ribosome". Nucleic Acids Res. 37 (2): 602–10. doi:10.1093/nar/gkn922. PMC 2632931 . PMID 19073700.
- ^ Shaw PC, Lee KM, Wong KB (May 2005). "Recent advances in trichosanthin, a ribosome-inactivating protein with multiple pharmacological properties". Toxicon. 45 (6): 683–9. doi:10.1016/j.toxicon.2004.12.024. PMID 15804517.
- ^ Zhao J, Ben LH, Wu YL, et al. (July 1999). "Anti-HIV agent trichosanthin enhances the capabilities of chemokines to stimulate chemotaxis and G protein activation, and this is mediated through interaction of trichosanthin and chemokine receptors". J. Exp. Med. 190 (1): 101–11. doi:10.1084/jem.190.1.101. PMC 2195565 . PMID 10429674.
- ^ Li MX, Yeung HW, Pan LP, Chan SI (November 1991). "Trichosanthin, a potent HIV-1 inhibitor, can cleave supercoiled DNA in vitro". Nucleic Acids Res. 19 (22): 6309–12. doi:10.1093/nar/19.22.6309. PMC 329144 . PMID 1659689.
External links
- Trichosanthin at the US National Library of Medicine Medical Subject Headings (MeSH)
UpToDate Contents
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English Journal
- A peptide tetramer Tk-tPN induces tolerance of cardiac allografting by conversion of type 1 to type 2 immune responses via the Toll-like receptor 2 signal-promoted activation of the MCP1 gene.
- Li Z1, Yang N2, Zhou L1, Gu P2, Wang H3, Zhou Y1, Zhou P3, Lu L1, Chou KY2.
- Immunology.Immunology.2016 Mar;147(3):355-66. doi: 10.1111/imm.12569.
- The plant protein trichosanthin (Tk) and its derived peptide tetramer Tk-tPN have been shown to stimulate the type 2 immune responses for treating autoimmune disease. This work explores the possibility of using Tk-tPN as a non-toxic immunosuppressant to induce transplantation tolerance using the mec
- PMID 26694804
- Trichosanthin reduces the viability of SU‑DHL‑2 cells via the activation of the extrinsic and intrinsic apoptotic pathways.
- Zhu Y1, Sun Y2, Cai Y1, Sha O3, Jiang W1.
- Molecular medicine reports.Mol Med Rep.2016 Jan;13(1):403-11. doi: 10.3892/mmr.2015.4531. Epub 2015 Nov 6.
- Previous studies have indicated that trichosanthin (TCS) exerts antitumor activity by inducing apoptosis in numerous tumor cell lines. However, the effects of TCS on lymphoma remain to be elucidated. The current study demonstrated that TCS inhibited the proliferation of thirteen lymphoma cell lines
- PMID 26548896
- A porcine model of early atrial fibrillation using a custom-built, radio transmission-controlled pacemaker.
- Schwarzl M1, Alogna A2, Zweiker D3, Verderber J3, Huber S4, Manninger M3, Scherr D3, Antoons G3, Pieske BM2, Post H5, Lueger A6.
- Journal of electrocardiology.J Electrocardiol.2015 Dec 23. pii: S0022-0736(15)00433-1. doi: 10.1016/j.jelectrocard.2015.12.012. [Epub ahead of print]
- Mechanisms underlying atrial remodeling toward atrial fibrillation (AF) are incompletely understood. We induced AF in 16 pigs by 6weeks of rapid atrial pacing (RAP, 600bpm) using a custom-built, telemetrically controlled pacemaker. AF evolution was monitored three times per week telemetrically in un
- PMID 26803554
Japanese Journal
- 能年 義輝
- 岡山大学農学部学術報告 103, 31-36, 2014-02-01
- … The isolated compound, imprimatin C1 activatesthe expression of defense-related genes independent ofpathogen and functions as a weak analog of salicylic acid(SA). …
- NAID 120005367631
- EFFICIENT OXIDATIVE SPIROLACTAMIZATION BY μ-OXO BRIDGED HETEROCYCLIC HYPERVALENT IODINE COMPOUND (Dedicated to Professor Victor Snieckus on the occasion of his 77th birthday)
- Dohi Toshifumi,Mochizuki Eisuke,Yamashita Daisuke [他]
- Heterocycles : an international journal for reviews and communications in heterocyclic chemistry 88(1), 245-260, 2014-01-01
- NAID 40019928143
- 医薬化合物の結晶発明に関する最近の判決動向 (ミニ特集 医薬品を題材とした知的財産上の論点について)
- 中村 敏夫
- 知財管理 = Intellectual property management 64(1), 33-46, 2014-01
- NAID 40019942588
Related Links
- In 1989, Project Inform ran an unauthorised trial of a drug known as "Compound Q", made from the extract of a cucumber-like plant grown in southeast Asia. Because FDA-run trials of the compound were thought by Project Inform to be ...
- 30 May 2006 ... One of the drugs they wanted was this one: trichosanthin, better known as Compound Q, the Chinese abortion and cancer drug. It was tantalizing because it killed HIV-infected cells in the test tube. The FDA promised human ...
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★リンクテーブル★
[★]
- 英
- compound Q
- 関
- トリコサンチン
[★]
トリコサンチン
- 関
- compound Q
[★]
- 関
- combination、compositus、mixture
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