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1. 内視鏡的逆行性胆管膵管造影（ERCP）後膵炎 post endoscopic retrograde cholangiopancreatography ercp pancreatitis
2. 持続的腎代替療法中の抗凝固療法 anticoagulation for continuous renal replacement therapy
3. 急性膵炎のマネージメント management of acute pancreatitis

English Journal

The serine protease inhibitor camostat inhibits influenza virus replication and cytokine production in primary cultures of human tracheal epithelial cells.

Yamaya M1, Shimotai Y2, Hatachi Y3, Lusamba Kalonji N4, Tando Y5, Kitajima Y6, Matsuo K7, Kubo H4, Nagatomi R6, Hongo S2, Homma M8, Nishimura H8.
Pulmonary pharmacology & therapeutics.Pulm Pharmacol Ther.2015 Aug;33:66-74. doi: 10.1016/j.pupt.2015.07.001. Epub 2015 Jul 10.
BACKGROUND: Serine proteases act through the proteolytic cleavage of the hemagglutinin (HA) of influenza viruses for the entry of influenza virus into cells, resulting in infection. However, the inhibitory effects of serine protease inhibitors on influenza virus infection of human airway epithelial
PMID 26166259

Zhou Y1, Vedantham P2, Lu K3, Agudelo J3, Carrion R Jr4, Nunneley JW4, Barnard D5, Pöhlmann S6, McKerrow JH7, Renslo AR2, Simmons G8.
Antiviral research.Antiviral Res.2015 Apr;116:76-84. doi: 10.1016/j.antiviral.2015.01.011. Epub 2015 Feb 7.
In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins by host cell proteases. The respective enzymes are thus excellent targets for antiviral intervention. In cell culture, a
PMID 25666761

The serine protease inhibitor camostat mesilate attenuates the progression of chronic kidney disease through its antioxidant effects.

Ueda M1, Uchimura K, Narita Y, Miyasato Y, Mizumoto T, Morinaga J, Hayata M, Kakizoe Y, Adachi M, Miyoshi T, Shiraishi N, Kadowaki D, Sakai Y, Mukoyama M, Kitamura K.
Nephron.Nephron.2015;129(3):223-32. doi: 10.1159/000375308. Epub 2015 Mar 3.
BACKGROUND/AIMS: We have so far demonstrated the renoprotective effect of camostat mesilate (CM) in 5/6 nephrectomized rats at least partly through its antioxidant effect. However, precise mechanisms were not fully clarified. Therefore, we now examined the renoprotective and antioxidant mechanisms o
PMID 25766432

Efficacy of camostat mesilate against dyspepsia associated with non-alcoholic mild pancreatic disease

SAI Jin Kan,SUYAMA Masafumi,KUBOKAWA Yoshihiro,MATSUMURA Yuji,INAMI Koichi,WATANABE Sumio
Journal of gastroenterology 45(3), 335-341, 2010-03-01
NAID 10027215227

PE-162 Poly(lactic-co-glycolic acid) Nanospheres Containing Protease Inhibitors, Camostat Mesilate and Nafamostat Mesilate : Therapeutic Potential for Treating Atherosclerosis(Cardiovascular pharmacology, basic/clinical(03)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

Fujii Satoshi,Noda Yasuhiro,Hazemoto Norio
Circulation journal : official journal of the Japanese Circulation Society 72(Supplement_I), 400-401, 2008-03-01
NAID 110006798051

英: camostat
化: メシル酸カモスタット camostat mesilate カモスタットメシル酸塩
商: アーチメント、カモエント、カモスタール、カモステート、カモストン、カモタット、カルモザシン、パンクレール、パンルーク、フオイパン、メシタット、メシルパン、モスパン、ラインタット、リーナック、リビリスター、レセプロン
関: 他に分類されない代謝性医薬品

フオイパン錠100mg

本剤は経口投与ですみやかに生体のキニン生成系、線溶系、凝固系及び補体系に作用し、その酵素活性をすみやかに阻害し異常亢進を抑制することにより、慢性膵炎の炎症症状と疼痛の緩解並びにアミラーゼ値の改善に効果が認められている。また、術後食道内に逆流する消化液中のトリプシンを阻害することにより、術後逆流性食道炎の改善に効果が認められている。