- 同
- BSEP
WordNet
- supply in great quantities; "Pump money into a project"
- a low-cut shoe without fastenings
- a mechanical device that moves fluid or gas by pressure or suction
- deliver forth; "pump bullets into the dummy"
- draw or pour with a pump
- flow intermittently
- move up and down; "The athlete pumps weights in the gym"
- operate like a pump; move up and down, like a handle or a pedal; "pump the gas pedal"
- question persistently; "She pumped the witnesses for information"
- raise (gases or fluids) with a pump
- sprinkle as if with salt; "the rebels had salted the fields with mines and traps"
- a compound formed by replacing hydrogen in an acid by a metal (or a radical that acts like a metal)
- preserve with salt; "people used to salt meats on ships"
- the taste experience when common salt is taken into the mouth (同)saltiness, salinity
- white crystalline form of especially sodium chloride used to season and preserve food (同)table_salt, common salt
- (of speech) painful or bitter; "salt scorn"- Shakespeare; "a salt apology"
- add salt to
- add zest or liveliness to; "She salts her lectures with jokes"
- transfer (electronic data) out of a database or document in a format that can be used by other programs
- commodities (goods or services) sold to a foreign country (同)exportation
- cause to spread in another part of the world; "The Russians exported Marxism to Africa"
- sell or transfer abroad; "we export less than we import and have a negative trade balance"
- a digestive juice secreted by the liver and stored in the gallbladder; aids in the digestion of fats (同)gall
- (used especially of meats) preserved in salt (同)salt-cured, brine-cured
PrepTutorEJDIC
- 『ポンプ』 / 《単数形で》ポンプで空気(ガス)を入れること / 《副詞[句]を伴って》〈気体・液体〉‘を'『ポンプで入れる』(『出す』) / …‘から'ポンプで水(など)を除く《+『out』+『名』,+『名』+『out』》 / …‘に'ポンプで空気(など)を満たす《+『up』+『名』,+『名』+『up』》 / (ポンプのハンドルのように)…‘を'上下(前後)に動かす / 《話》(…について)〈人〉‘を'あの手この手で問いただす(聞き出す)《+『名』+『for』(『about』)+『名』》 / 《話》(人に)〈知識など〉‘を'詰め込む《+『名』+『into』+『名』〈人〉》;(人から)〈情報など〉‘を'引き出す《+『名』+『out of』+『名』〈人〉》 / ポンプを使う / (ポンプのように)上下に動く,鼓動する / 〈水が〉噴出する
- パンプス(ひもや金具がなく,甲のあいた靴)
- 〈U〉『塩』食塩 / 〈U〉(化学で)塩 / 《複数形で》薬用塩類(Epsom salt[s],smelling salts) / 〈U〉生気(刺激,興趣)を与えるもの / 〈C〉《話》(特に老練な)水夫 / 塩の,塩を含んでいる;塩気のある,塩辛い / 塩漬けにした / (土地が)塩につかった / 塩信でできた,塩水の中で育つ / 〈食べ物〉‘を'塩で味をつける;〈肉・魚など〉‘を'塩漬けにして保存する《+『名』+『down』,+『down』+『名』》 / 《受動態で》(…で)〈言葉・話なで〉‘を'ぴりっとさせる,‘に'味をつける《+『名』+『with』+『名』》
- (外国へ)〈商品〉‘を'『輸出する』《+『名』+『to』+『名』》 / 〈C〉『輸出品』 / 〈U〉(…の)『輸出』《+『of』+『名』》
- 胆汁(たんじゅう) / かんしゃく;不きげん
- 塩で味をつけて,塩味の;塩漬けの
UpToDate Contents
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- 1. 抱合型高ビリルビン血症関連の遺伝性疾患 inherited disorders associated with conjugated hyperbilirubinemia
- 2. 薬と肝臓：薬物性肝障害のパターン drugs and the liver patterns of drug induced liver injury
English Journal
- Endothelin-1 and -3 induce choleresis in the rat through ETB receptors coupled to nitric oxide and vagovagal reflexes.
- Rodriguez MR, Soria LR, Ventimiglia MS, Najenson AC, Di María A, Dabas P, Fellet A, Marinelli RA, Vatta MS, Bianciotti LG.SourceCátedras de Fisiopatología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
- Clinical science (London, England : 1979).Clin Sci (Lond).2013 Dec;125(11):521-32. doi: 10.1042/CS20120633.
- We have reported previously that centrally applied ET (endothelin)-1 and ET-3 induce either choleresis or cholestasis depending on the dose. In the present study, we sought to establish the role of these endothelins in the short-term peripheral regulation of bile secretion in the rat. Intravenously
- PMID 23642207
- The adverse outcome pathway concept: A pragmatic tool in toxicology.
- Vinken M.SourceDepartment of Toxicology, Center for Pharmaceutical Research (CePhar), Vrije Universiteit Brussel (VUB), Belgium. Electronic address: mvinken@vub.ac.be.
- Toxicology.Toxicology.2013 Oct 4;312C:158-165. doi: 10.1016/j.tox.2013.08.011. Epub 2013 Aug 23.
- Adverse outcome pathways (AOPs) are novel tools in toxicology and human risk assessment with broad potential. AOPs are designed to provide a clear-cut mechanistic representation of critical toxicological effects that span over different layers of biological organization. AOPs share a common structur
- PMID 23978457
- Differential activation of the human farnesoid X receptor depends on the pattern of expressed isoforms and the bile acid pool composition.
- Vaquero J, Monte MJ, Dominguez M, Muntané J, Marin JJ.SourceLaboratory of Experimental Hepatology and Drug Targeting (HEVEFARM), Biomedical Research Institute of Salamanca (IBSAL), University of Salamanca, Salamanca, Spain.
- Biochemical pharmacology.Biochem Pharmacol.2013 Oct 1;86(7):926-39. doi: 10.1016/j.bcp.2013.07.022. Epub 2013 Aug 6.
- The farnesoid X receptor (FXR) is a key sensor in bile acid homeostasis. Although four human FXR isoforms have been identified, the physiological role of this diversity is poorly understood. Here we investigated their subcellular localization, agonist sensitivity and response of target genes. Measur
- PMID 23928191
Japanese Journal
- トランスポーター関連疾患に対する新規治療戦略の開発を指向した創薬研究
- 林 久允
- 薬学雑誌 134(10), 1007-1011, 2014
- NAID 40020237541
- トランスポーター関連疾患に対する新規治療戦略の開発を指向した創薬研究
- 林 久允
- 薬学雑誌. 乙号 134(10), 1007-1011, 2014
- … The bile salt export pump (BSEP/ABCB11), a member of the family of ATP-binding cassette transporters, is localized on the canalicular membrane of hepatocytes and predominantly mediates the biliary excretion of bile salts. …
- NAID 130004693883
- More Relevant Prediction for In Vivo Drug Interaction of Candesartan Cilexetil on Hepatic Bile Acid Transporter BSEP Using Sandwich-cultured Hepatocytes
- , ,
- Drug Metabolism and Pharmacokinetics 29(1), 94-96, 2014
- … Bile salt export pump (BSEP) plays a major role in biliary secretion of bile salts; … Drug interaction on hepatic bile canalicular transporters such as BSEP with prodrugs that are rapidly metabolized has not been evaluated well. …
- NAID 130004463341
Related Links
- BSEP (bile salt export pump, ABCB11)は、肝臓からの胆汁酸排泄に極めて重要な、排出型 ABC トランスポーターです。 BSEP は主にタウロコール酸などの抱合胆汁酸を肝細胞から胆管へ排泄しているため、胆汁酸排泄を阻害する薬剤は ...
- Canalicular secretion of bile salts mediated by the bile salt export pump Bsep constitutes the major driving force for the generation of bile flow. Bsep is a member of the B-family of the super family
Related Pictures
★リンクテーブル★
| リンク元 | 「BSEP deficiency」 |
| 関連記事 | 「export」「pump」「salt」「pumping」「bile salt」 |
「BSEP deficiency」
「export」
- n.
- v.
- 輸出する、排出する、運び出す
- 関
- drain、draining、efferent、egest、egestion、eject、eliminate、elimination、emission、emit、excrete、excretion、expel
「pump」
- n.
- v.
- ポンピングする
- 関
- pumping
「salt」
- n.
- 関
- saline
「pumping」
- n.
- 関
- pump