関: benzathine penicillin G、benzylpenicillin、benzylpenicillin benzathine hydrate、benzylpenicillin potassium、penicillin G

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/02/10 08:21:03」(JST)

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Benzathine benzylpenicillin (rINN) is a form of penicillin also known as benzathine penicillin. It is an antibiotic useful for the treatment of a number of bacterial infections.

It is slowly absorbed into the circulation, after intramuscular injection, and hydrolysed to benzylpenicillin in vivo. It is the drug-of-choice when prolonged low concentrations of benzylpenicillin are required and appropriate, allowing prolonged antibiotic action over 2–4 weeks after a single IM dose. It is marketed by Wyeth under the trade name Bicillin L-A.

Medical uses for benzathine penicillin include: prevention of rheumatic fever and early or latent syphilis.^[1]

It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.^[2]

Adverse effects

Compendial status

British Pharmacopoeia ^[3]

References

^ Rossi S, editor, ed. (2006). Australian Medicines Handbook. Adelaide: Australian Medicines Handbook. ISBN 0-9757919-2-3.
^ "WHO Model List of EssentialMedicines". World Health Organization. October 2013. Retrieved 22 April 2014.
^ British Pharmacopoeia Commission Secretariat. "Index (BP 2009)". Retrieved 26 March 2010.

UpToDate Contents

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1. 早期梅毒の病因、臨床症状、および治療 pathogenesis clinical manifestations and treatment of early syphilis
2. 連鎖球菌扁桃咽頭炎の治療および予防 treatment and prevention of streptococcal tonsillopharyngitis
3. 急性リウマチ熱の治療および予防 treatment and prevention of acute rheumatic fever
4. 先天梅毒：評価、マネージメント、および予防 congenital syphilis evaluation management and prevention
5. 後期梅毒の病因、臨床症状、および治療 pathogenesis clinical manifestations and treatment of late syphilis

English Journal

Adverse effects associated with inadvertent intravenous penicillin G procaine-penicillin G benzathine administration in two dogs and a cat.

Kaplan MI, Lee JA, Hovda LR, Brutlag A.SourceSection of Emergency and Critical Care, Department of Clinical Studies, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108, USA. justmemeg@gmail.com
Journal of the American Veterinary Medical Association.J Am Vet Med Assoc.2011 Feb 15;238(4):507-10.
PMID 21320022

Benzathine penicillin for recurrence of rheumatic fever: the jury is still out.

Pediatric cardiology.Pediatr Cardiol.2011 Feb;32(2):247.
PMID 21113586

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リンク元	「ベンジルペニシリン」「benzylpenicillin benzathine hydrate」「benzylpenicillin potassium」「ベンジルペニシリンベンザチン」「benzathine penicillin G」
関連記事	「benzylpenicillin」

「ベンジルペニシリン」

Benzathine benzylpenicillin
Combination of
Benzylpenicillin	Antibiotic
Benzathine	Stabilizer
Clinical data
AHFS/Drugs.com	International Drug Names
Legal status	?
Identifiers
CAS number	1538-09-6
ATC code	J01CE08
PubChem	CID 15232
ChemSpider	14498
UNII	SSZ1S4I0US
ChEBI	CHEBI:51352
ChEMBL	CHEMBL1200651
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