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Recurrent extracranial internal carotid artery vasospasm diagnosed by serial magnetic resonance angiography and superselective transarterial injection of a calcium channel blocker.

Shimoda Y1, Fujimura M2, Kimura N3, Ezura M3, Uenohara H3, Tominaga T4.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.J Stroke Cerebrovasc Dis.2014 May-Jun;23(5):e383-7. doi: 10.1016/j.jstrokecerebrovasdis.2013.12.050. Epub 2014 Mar 19.
Recurrent vasospasm of the extracranial internal carotid artery (ICA) is extremely rare, and optimal management is unclear. A 25-year-old woman developed transient dysarthria and left-sided hemiparesis. Initial magnetic resonance (MR) imaging showed spotty acute infarction in the right temporal lobe
PMID 24656242

Neuroprotective effects of amlodipine besylate and benidipine hydrochloride on oxidative stress-injured neural stem cells.

Choi NY1, Choi H2, Park HH2, Lee EH1, Yu HJ3, Lee KY2, Joo Lee Y2, Koh SH4.
Brain research.Brain Res.2014 Mar 10;1551:1-12. doi: 10.1016/j.brainres.2014.01.016. Epub 2014 Jan 16.
Hypertension is associated with oxidative stress. Amlodipine besylate (AB) and benidipine hydrochloride (BH), which are Ca(2+) antagonists, have been reported to reduce oxidative stress. In this study, we examined the neuroprotective effects of AB and BH on oxidative stress-injured neural stem cells
PMID 24440775

Benidipine suppresses in situ proliferation of leukocytes and slows the progression of renal fibrosis in rat kidneys with advanced chronic renal failure.

Kazama I1, Baba A, Matsubara M, Endo Y, Toyama H, Ejima Y.
Nephron. Experimental nephrology.Nephron Exp Nephrol.2014;128(1-2):67-79. doi: 10.1159/000368080. Epub 2014 Oct 24.
BACKGROUND/AIMS: Leukocytes, such as lymphocytes and macrophages, predominantly express delayed rectifier K(+) channels (Kv1.3) in their plasma membranes. In our previous study, the overexpression of these channels in leukocytes was strongly associated with their proliferation in kidneys and the pro
PMID 25358915

市丸みどり
東京女子医科大学雑誌 83(2), 95-105, 2013-04-25
目的:アンジオテンシン受容体遮断薬とカルシウム拮抗薬の併用による降圧効果の機序について、DFA(Detrended Fluctuation Analysis)より得られるスケーリング指標を用いて判定した。,対象と方法:カルシウム拮抗薬およびアンジオテンシン受容体遮断薬との併用療法の有用性を研究することを目的としたJ-SUCCESS(Study of the Usefulness of Combin …
NAID 110009581136

Cutaneous pseudolymphoma due to benidipine hydrochloride with massive infiltration of eosinophils

市原絵美,奥村学,吉田史,河野洋平,大浦華代子,岩切智美,保田和哉,塩月理士,松田真理,水元貴美子,吉田裕樹,熊谷有紀,有森和彦
医療薬学 34(4), 366-373, 2008-04-10
… With this in mind, we evaluated the equivalence of the branded benidipine hydrochloride tablets and generics of it, by comparing such aspects as their passage through a nasogastric tube, and the characteristics of divided tablets. …
NAID 110006649688