ツッカーカンドル器官、Zuckerkandl器官
- 関
- para-aortic body
WordNet
- wind instrument whose sound is produced by means of pipes arranged in sets supplied with air from a bellows and controlled from a large complex musical keyboard (同)pipe_organ
- a fully differentiated structural and functional unit in an animal that is specialized for some particular function
- a government agency or instrument devoted to the performance of some specific function; "The Census Bureau is an organ of the Commerce Department"
- a periodical that is published by a special interest group; "the organ of the communist party"
PrepTutorEJDIC
- 『オルガン』,パイプオルガン(pipe organ),リードオルガン(reed organ),電子オルガン(electronic organ),手回しオルガン(barrel organ) / (動植物の)『器官』 / (政党・会社などの)機関誌,機関紙 / 《しばしば複数形で》(行動・実施などの)組織,機関
- 《所有・所属》…『の』,…のものである,…に属する・《材料・要素》…『でできた』,から成る・《部分》…『の』[『中の』] ・《数量・単位・種類を表す名詞に付いて》…の・《原因・動機》…『で』,のために(because of) ・《主格関係》…『の』,による,によって・《目的格関係》…『を』,の・《同格関係》…『という』・《関係・関連》…『についての』[『の』],の点で・《抽象名詞などと共に》…の[性質をもつ] ・《『It is』+『形』+『of』+『名』+『to』 doの形で,ofの後の名詞を意味上の主語として》・《分離》…『から』・《起原・出所》…『から』[『の』](out of) ・《『名』+『of』+『a』(『an』)+『名』の形で》…のような・《『名』+『of』+『mine』(『yours, his』など独立所有格)の形で》…の…・《時》(1)《副詞句を作って》…に《形容詞句を作って》…の・《時刻》《米》…前(to,《米》before)
- OLD French古[代]フランス語
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/10/09 09:10:34」(JST)
[Wiki en表示]
Organ of Zuckerkandl |
The abdominal aorta and its branches. (Organ of Zuckerkandl is not shown, but it usually appears alongside the abdominal aorta.)
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Identifiers |
TA |
A12.2.04.003 |
FMA |
15647 |
Anatomical terminology |
The organ of Zuckerkandl is a chromaffin body derived from neural crest located at the bifurcation of the aorta or at the origin of the inferior mesenteric artery. It can be the source of pheochromocytoma or paraganglioma.[1]
The term para-aortic body is also sometimes used to describe it, as it usually arises near the abdominal aorta, but this term can be the source of confusion, because the term "corpora paraaortica" is also used to describe the aortic body, which arises near the thoracic aorta. This diffuse group of neuroendocrine sympathetic fibres was first described by Emil Zuckerkandl, a professor of anatomy at the University of Vienna, in 1901.[2]
Some sources equate the "aortic bodies" and "paraaortic bodies",[3] while other sources explicitly distinguish between the two.[4][5] When a distinction is made, the "aortic bodies" are chemoreceptors which regulate circulation, while the "paraaortic bodies" are the chromaffin cells which manufacture catecholamines.
Contents
- 1 Structure
- 2 Function
- 3 Clinical significance
- 4 References
- 5 External links
Structure
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This section requires expansion. (September 2014) |
Function
Its physiological role is thought to be of greatest importance during the early gestational period as a homeostatic regulator of blood pressure, secreting catecholamines into the fetal circulation.
The organ itself regresses in the late third trimester and following birth to form the aorticosympathetic group of the adult paraganglia.
Clinical significance
Pathology
It can be the source of paraganglioma or pheochromocytoma.[6]
The organ of Zuckerkandl is of pathological significance in the adult as a common extra-adrenal site of pheochromocytoma though the most common extra-adrenal site is in the superior para-aortic region between the diaphragm and lower renal poles.[7]
Extra-adrenal tumors account for around 10% of all cases of pheochromocytoma.[8] Resection has been described.[9]
In addition to its endocrine effects, it can also cause obstructive pathology.[10]
References
- ^ Dossett, Lesly; Rudzinski, Erin; Blevins, Lewis; Chambers, Eugene (2007). "Malignant Pheochromocytoma of the Organ of Zuckerkandl Requiring Aortic and Vena Caval Reconstruction". Endocrine Practice 13 (5): 493–7. doi:10.4158/ep.13.5.493. PMID 17872352.
- ^ synd/3111 at Who Named It?
- ^ "organs of Zuckerkandl" at Dorland's Medical Dictionary
- ^ Aortic Bodies at the US National Library of Medicine Medical Subject Headings (MeSH)
- ^ Para-Aortic Bodies at the US National Library of Medicine Medical Subject Headings (MeSH)
- ^ Saurborn, Daniel P.; Kruskal, Jonathan B.; Stillman, Isaac E.; Parangi, Sareh (2003). "Best Cases from the AFIP". RadioGraphics 23 (5): 1279–86. doi:10.1148/rg.235035022. PMID 12975514.
- ^ Whalen, R. K.; Althausen, A. F.; Daniels, G. H. (1992). "Extra-adrenal pheochromocytoma". The Journal of urology 147 (1): 1–10. PMID 1729490.
- ^ Thompson, Robert W. (2002). "Detection and Management of Small Aortic Aneurysms". New England Journal of Medicine 346 (19): 1484–6. doi:10.1056/NEJM200205093461910. PMID 12000820.
- ^ Kravarusic, Dragan; Pinto-Rojas, Alfredo; Al-Assiri, Ali; Sigalet, David (2007). "Laparoscopic resection of extra-adrenal pheochromocytoma—Case report and review of the literature in pediatric patients". Journal of Pediatric Surgery 42 (10): 1780–4. doi:10.1016/j.jpedsurg.2007.06.025. PMID 17923216.
- ^ Blecha, Matthew; Galanopolous, Christos; Dharkar, Dilip; Salti, George (2005). "Massive Organ of Zuckerkandl Inducing Small Bowel Obstruction". Journal of the American College of Surgeons 201 (3): 480–1. doi:10.1016/j.jamcollsurg.2005.02.031. PMID 16125084.
External links
Anatomy of the endocrine system
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Pituitary gland |
Anterior |
- Pars intermedia
- Pars tuberalis
- Pars distalis
- Acidophil cell
- Somatotropic cell
- Prolactin cell
- Basophil cell
- Corticotropic cell
- Gonadotropic cell
- Thyrotropic cell
- Chromophobe cell
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Posterior |
- Pars nervosa
- Median eminence
- Stalk
- Pituicyte
- Herring bodies
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Thyroid gland |
- Thyroid isthmus
- Follicular cell
- Parafollicular cell
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Parathyroid gland |
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Adrenal gland |
Cortex |
- Zona glomerulosa
- Zona fasciculata
- Zona reticularis
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Medulla |
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Gonads |
- Testicle
- Ovary
- Theca interna
- Granulosa cell
- Corpus luteum
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Islets of pancreas |
- Alpha cell
- Beta cell
- PP cell
- Delta cell
- Epsilon cell
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Pineal gland |
- Pinealocyte
- Corpora arenacea
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Other |
- Enteroendocrine cell
- Paraganglia
- Placenta
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Index of hormones
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Description |
- Glands
- Hormones
- thyroid
- mineralocorticoids
- Physiology
- Development
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Disease |
- Diabetes
- Congenital
- Neoplasms and cancer
- Other
- Symptoms and signs
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Treatment |
- Procedures
- Drugs
- calcium balance
- corticosteroids
- oral hypoglycemics
- pituitary and hypothalamic
- thyroid
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UpToDate Contents
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English Journal
- Primary Retroperitoneal Inter-aorto-Caval Paraganglioma of the Organ of Zuckerkandl.
- Vikas V1, Ahmed Z1, Singh O1, Pal SS2, Songra MC3.
- Journal of clinical and diagnostic research : JCDR.J Clin Diagn Res.2014 Jul;8(7):ND06-7. doi: 10.7860/JCDR/2014/6781.4619. Epub 2014 Jul 20.
- Tumour that arise from chromaffin cells at extra-adrenal locations are termed paragangliomas which are rare tumour. The organ of Zuckerkandl located along aortic bifurcation is the most common site of their occurrence. Herein, we report a case of 20-year-old male with large abdomino-pelvic paragangl
- PMID 25177602
- Role of rapid sequence whole-body MRI screening in SDH-associated hereditary paraganglioma families.
- Jasperson KW1, Kohlmann W, Gammon A, Slack H, Buchmann L, Hunt J, Kirchhoff AC, Baskin H, Shaaban A, Schiffman JD.
- Familial cancer.Fam Cancer.2014 Jun;13(2):257-65. doi: 10.1007/s10689-013-9639-6.
- Patients with germline mutations in one of the SDH genes are at substantially increased risk of developing paragangliomas, pheochromocytomas (pheos), and other tumors (all combined referred to as SDH-related tumors). However, limited data exist on screening in SDH mutation carriers and no studies ha
- PMID 23934599
- Malignant melanotic schwannian tumor: a clinicopathologic, immunohistochemical, and gene expression profiling study of 40 cases, with a proposal for the reclassification of "melanotic schwannoma".
- Torres-Mora J1, Dry S, Li X, Binder S, Amin M, Folpe AL.
- The American journal of surgical pathology.Am J Surg Pathol.2014 Jan;38(1):94-105. doi: 10.1097/PAS.0b013e3182a0a150.
- Melanotic schwannomas (MSs), variably associated with the Carney complex, are rare tumors that usually involve spinal nerve roots but may occur in other locations. Clinicopathologic evaluation poorly predicts the behavior of MS. Fewer than 200 cases have been reported. We report a series of 40 well-
- PMID 24145644
Japanese Journal
- エピネフリンが異常高値を示した副腎外褐色細胞腫の一例
- 菅原 隆,清水 公,瀬川 郁夫
- 日本内分泌学会雑誌 72(3), 551-560, 1996-05-20
- … We reported a case of a 72-year-old man with an extra-adrenal pheochromocytoma secreting excessive epinephrine (E). … An upper gastrointestinal series and computed tomography of the abdomen revealed an ovoid mass (diameter, approximately 5×6 cm) overlying the abdominal aorta and the inferior vena cava between the second and the third lumbar vertebra. …
- NAID 10009419976
- 42.Organ of Zuckerkandl 原発神経節芽腫の1例(第24回 日本小児外科学会東海地方会)
- Fine-needle aspiration cytology of pheochromocytoma-ganglioneuroma of the organ of Zuckerkandl
Related Links
- para-aortic bodies [par″ah-a-or´tik] small masses of chromaffin cells near the sympathetic ganglia along the abdominal aorta that secrete norepinephrine. ... They are most frequently found in the organ of Zuckerkandl (around the root of ...
- The organ of Zuckerkandl comprises of a small mass of chromaffin cells derived from neural crest located along the aorta, beginning cranial to the superior mesenteric artery or renal arteries and extending to the level of the aortic ...
★リンクテーブル★
[★]
- 英
- paraganglion、paraganglia、paraganglionic
- 同
- パラガングリオン、大動脈クロム親和体 aortic chromaffin body、ツッカーカンドル器官 organ of Zuckerkandl
- 関
- 大動脈傍体 paraaortic bodies
[★]
- 英
- organ of Zuckerkandl
- 関
- 大動脈傍体、Zuckerkandl器官、傍神経節
[★]
- 英
- organ of Zuckerkandl
- 関
- ツッカーカンドル器官
[★]
大動脈傍体
- 関
- organ of Zuckerkandl
[★]