- 関
- anthelmintic、antiparasitic agent、antiparasitic drug、vermicidal、vermicide
WordNet
- capable of expelling or destroying parasitic worms (同)anthelminthic, helminthic, parasiticidal
- an agent that kills worms (especially those in the intestines)
Wikipedia preview
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Skeletal formula of metronidazole
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Contents
- 1 Antinematodes
- 2 Anticestodes
- 3 Antitrematodes
- 4 Antiamoebics
- 5 Antiprotozoals
- 6 References
- 7 See also
Antinematodes
Ancylostoma caninum, a type of hookworm, attached to the intestinal mucosa.
- Mebendazole (for most nematode infections)
- Pyrantel pamoate (for most nematode infections)
- Thiabendazole (for roundworm infections)
- Diethylcarbamazine (for treatment of Lymphatic filariasis)
- Ivermectin (for prevention of river blindness)
Anticestodes
- Niclosamide (for tapeworm infections)
- Praziquantel (for tapeworm infections)
- Albendazole (broad spectrum)
Antitrematodes
Antiamoebics
Antiprotozoals
- Melarsoprol (for treatment of sleeping sickness caused by Trypanosoma brucei)
- Eflornithine (for sleeping sickness)
- Metronidazole (for vaginitis caused by Trichomonas)
- Tinidazole (for intestinal infections caused by Giardia)
- Miltefosine (for the treatment of visceral and cutaneous leishmaniasis, currently undergoing investigation for Chagas disease)
References
See also
- Balsam of Peru, which has antiparasitic attributes
- Naegleria fowleri
- Balamuthia mandrillaris
Antiparasitics – antiprotozoal agents – Excavata antiparasitics (P01)
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Discicristata |
Trypanosomiasis
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- African trypanosomiasis: ornithine (Eflornithine#)
- arsenical (Melarsoprol#)
- benzamidine (Pentamidine#)
- naphthalenesulfonate (Suramin#)
Chagas disease: nitroimidazole (Benznidazole#)
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Leishmaniasis
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- macrolide (Amphotericin B#)
Pentavalent antimonials (Meglumine antimoniate#, Sodium stibogluconate)
- benzamidine (Pentamidine#)
- phosphorylcholine (Miltefosine)
- neomycin (Paromomycin)
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PAM
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- macrolide (Amphotericin B)
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|
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Trichozoa |
Giardiasis
|
- nitroimidazole (Metronidazole#, Tinidazole)
- benzimidazole (Albendazole)
- thiazole (Nitazoxanide)
- nitrofuran (Furazolidone)
- aminoacridine (Quinacrine)
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Trichomoniasis
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- nitroimidazole (Carnidazole, Metronidazole#, Tinidazole)
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Dientamoebiasis
|
- nitroimidazole (Metronidazole
- Secnidazole)
- oxyquinoline (Iodoquinol)
- tetracycline (Doxycycline)
- neomycin (Paromomycin)
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|
|
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
Index of protozoan infection
|
|
Description |
- Alveolata
- Amoebozoa
- Excavata
- Protist
|
|
Disease |
- Amoebozoa
- Chromalveolate
- Excavata
|
|
Treatment |
- Drugs
- amoeboa
- chromalveolate
- excavata
|
|
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Antiparasitics – antiprotozoal agents – Chromalveolate antiparasitics (P01)
|
|
Alveo-
late |
Apicom-
plexa |
Conoidasida/
(Coccidiostats) |
Cryptosporidiosis |
|
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Isosporiasis |
- trimethoprim/sulfamethoxazole#
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Toxoplasmosis |
- pyrimethamine
- sulfadiazine
|
|
|
Aconoidasida |
Malaria |
Individual
agents |
Hemozoin
inhibitors |
aminoquinolines |
- (4-): amodiaquine#
- chloroquine#
- (8-): primaquine#
- pamaquine
|
|
4-methanolquinolines |
- mefloquine#
- quinine#
- quinidine
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Other |
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Antifolates |
DHFR inhibitors
(antifols) |
- proguanil#
- chlorproguanil
|
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Sulfonamides |
- sulfadoxine
- sulfamethoxypyrazine
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Coformulation |
- sulfadoxine/pyrimethamine (SP)#
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|
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Sesquiterpene
lactones |
- artemether#
- artesunate#
- dihydroartemisinin
- artemotil
- artemisinin
|
|
Other |
- atovaquone (with proguanil as Malarone)
- tetracycline
- doxycycline#
- clindamycin
- pyronaridine
- piperaquine
|
|
|
Combi-
nations |
Fixed-dose (coformulated) ACTs |
- artemether/lumefantrine#
- artesunate/amodiaquine (ASAQ)
- artesunate/mefloquine (ASMQ)
- dihydroartemisinin/piperaquine
- artesunate/pyronaridine
|
|
Other combinations
(not co-formulated) |
- artesunate/SP
- artesunate/mefloquine
- quinine/tetracycline
- quinine/doxycycline
- quinine/clindamycin
|
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|
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Babesiosis |
|
|
|
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Cilio-
phora |
- Balantidiasis: Tetracycline
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|
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Hetero-
kont |
- Blastocystosis: Metronidazole
|
|
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
Index of protozoan infection
|
|
Description |
- Alveolata
- Amoebozoa
- Excavata
- Protist
|
|
Disease |
- Amoebozoa
- Chromalveolate
- Excavata
|
|
Treatment |
- Drugs
- amoeboa
- chromalveolate
- excavata
|
|
|
Antiparasitics – antiprotozoal agents – agents against amoebozoa/amebicide (P01)
|
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Entamoeba |
Tissue amebicides
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Nitroimidazole derivatives
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- Metronidazole#
- Tinidazole
- Ornidazole
- Nimorazole
- Secnidazole
- Azanidazole
- Propenidazole
|
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Other
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- isoquinoline (Emetine/Dehydroemetine)
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Luminal amebicides
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Hydroxyquinoline derivatives
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- Cl (Chlorquinaldol)
- Br (Tilbroquinol
- Broxyquinoline)
- I (Diiodohydroxyquinoline)
- I,Cl (Clioquinol)
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Dichloroacetamide derivatives
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- Diloxanide#
- Clefamide
- Etofamide
- Teclozan
|
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Aminoglycoside
|
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Other/ungrouped
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- arsenic (Arsthinol
- Difetarsone
- Glycobiarsol)
- phenanthroline (Phanquinone)
- aminoacridine (Mepacrine)
- quinazoline (Trimetrexate)
- thiazole (Tenonitrozole)
- sesquiterpene (Fumagillin)
|
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Acanthamoeba |
- Propamidine
- Chlorhexidine
|
|
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
Index of protozoan infection
|
|
Description |
- Alveolata
- Amoebozoa
- Excavata
- Protist
|
|
Disease |
- Amoebozoa
- Chromalveolate
- Excavata
|
|
Treatment |
- Drugs
- amoeboa
- chromalveolate
- excavata
|
|
|
Antiparasitics – Anthelmintics (P02) and Endectocides (QP54)
|
|
Antiplatyhelmintic agents |
Antitrematodals
(schistosomicides)
|
Binds tubulin
|
|
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AI
|
|
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Other/unknown
|
- quinoline
- Praziquantel#
- Oxamniquine#
- phenol
- thiazole
- arylsulfonate
|
|
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Anticestodals
(taeniacides)
|
Binds tubulin
|
|
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Other/unknown
|
- salicylanilide
- aminoacridine
- butyrophenone
- chlorophenol
|
|
|
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Antinematodal agents
(including
macrofilaricides) |
Binds tubulin
|
- benzimidazole
- Mebendazole#
- Albendazole#
- Thiabendazole
- Fenbendazole
- Ciclobendazole
- Flubendazole
|
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Glutamate-gated chloride channel, GABA receptor
|
- avermectins
- Abamectin
- Doramectin
- Emamectin
- Ivermectin
- Selamectin
- milbemycins
- Moxidectin
- Milbemycin oxime
|
|
NMDA
|
- tetrahydropyrimidine
- Pyrantel#
- Pyrantel pamoate
- Oxantel
|
|
Other/unknown
|
- piperazine
- Piperazine
- Diethylcarbamazine#
- thiazole
- quinolinium
- benzylammonium
- naphthalenesulfonate
- Tribendimidine
|
|
|
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
Index of parasites and pests
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|
Description |
- Helmintic, arthropod
- Acari
|
|
Disease |
- Helminthiases
- Arthropod
- lice
- tick- and mite-born diseases
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Treatment |
|
|
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UpToDate Contents
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English Journal
- The Case for the Use of PPARγ Agonists as an Adjunctive Therapy for Cerebral Malaria.
- Serghides L.SourceSandra A. Rotman Laboratories, McLaughlin-Rotman Centre for Global Health, Toronto General Hospital, University Health Network, 101 College Street, Suite 10-359, Toronto, ON, Canada M5G 1L7.
- PPAR research.PPAR Res.2012;2012:513865. Epub 2011 Jun 9.
- Cerebral malaria is a severe complication of Plasmodium falciparum infection associated with high mortality even when highly effective antiparasitic therapy is used. Adjunctive therapies that modify the pathophysiological processes caused by malaria are a possible way to improve outcome. This review
- PMID 21772838
- In vitro antitrypanosomal and antileishmanial activity of plants used in Benin in traditional medicine and bio-guided fractionation of the most active extract.
- Bero J, Hannaert V, Chataigne G, Herent MF, Quetin-Leclercq J.SourceUniversite catholique de Louvain, Louvain Drug Research Institute, Pharmacognosy Research Group, Avenue E. Mounier, 72, B-1200 Brussels, Belgium.
- Journal of ethnopharmacology.J Ethnopharmacol.2011 Sep 2;137(2):998-1002. Epub 2011 Jul 18.
- ETHNOPHARMACOLOGICAL RELEVANCE: The aim of the study was to evaluate the in vitro antitrypanosomal and antileishmanial activity of crude extracts of 10 plant species traditionally used in Benin to treat parasitic infections.MATERIALS AND METHODS: For each species, dichloromethane, methanol and aqueo
- PMID 21782916
Japanese Journal
- 10 キチナーゼ阻害剤Argifinの固相全合成と分子設計、in situクリックケミストリーを駆使した新規キチナーゼ阻害剤の創製(口頭発表の部)
- 砂塚 敏明,廣瀬 友靖,菅原 章公,井口 加奈美,遠藤 綾子,斉藤 佳史,山本 剛,宇井 英明,合田 浩明,広野 修一,塩見 和朗,渡邉 剛志,Sharpless K. Barry,大村 智
- 天然有機化合物討論会講演要旨集 (50), 83-88, 2008-09-01
- … Consequently, chitinases have been expected to be specific target for antifungal, insecticidal and antiparasitic agents. …
- NAID 110007066770
- Effects of moxidectin on coprophagous insects in cattle dung pats in Japan
- IWASA Mitsuhiro,SUZUKI Natsuki,MARUYAMA Mikiko
- Applied entomology and zoology 43(2), 271-280, 2008-05-25
- … Effects of the antiparasitic drug moxidectin were studied in laboratory and field experiments in Hokkaido, Japan by pour-on administrations (500μg/kg) on a target pest Haematobia irritans Linnaeus, nontarget coprophagous flies represented by Neomyia cornicina (Fabricius), and the dung beetle Caccobius jessoensis Harold. …
- NAID 110006684230
Related Links
- Antiparasitic. From Wikipedia, the free encyclopedia. Jump to: navigation, search. Skeletal formula of metronidazole .... Retrieved from "http://en.wikipedia.org/wiki/ Antiparasitic". Categories: Antiparasitic agents | Antiinfective agent stubs ...
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- 関
- antiparasitic、antiparasitic agent、antiparasitic drug、vermicidal、vermicide
[★]
- 英
- antiparasitic agent、antiparasitic drug、antiparasitic
- 関
- 駆虫性、駆虫薬、抗寄生虫
[★]
- 英
- anthelmintic、antiparasitic、vermicidal
- 関
- 駆虫薬、抗寄生虫薬、抗寄生虫
[★]
- 関
- anthelmintic、antiparasitic、antiparasitic agent、antiparasitic drug
[★]
- 英
- antiparasitic
- 関
- 駆虫性、駆虫薬、抗寄生虫薬
[★]
- 関
- anthelmintic、antiparasitic、antiparasitic agent、vermicide
[★]
- 関
- anthelmintic、antiparasitic、antiparasitic drug、vermicide