WordNet
- an ordered array of the components of an emission or wave
- a broad range of related objects or values or qualities or ideas or activities
- capable of destroying or inhibiting the growth of disease-causing microorganisms (同)antimicrobic
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- スペクトル(光がプリズムを通過するとき生じる色の帯) / (電磁波・音波などの)範囲,スペクトル / (多様だが関連あるものの)連続[範囲]《+『of』+『名』》
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- 1. ペニシリン penicillins
- 2. セフェム系 cephalosporins
- 3. フルオロキノロン類 fluoroquinolones
- 4. 基質特異性拡張型β-ラクタマーゼ extended spectrum beta lactamases
- 5. 緑膿菌感染症に対する抗菌薬治療の原則 principles of antimicrobial therapy of pseudomonas aeruginosa infections
English Journal
- Development of an indirect competitive assay-based aptasensor for highly sensitive detection of tetracycline residue in honey.
- Wang S1, Yong W2, Liu J1, Zhang L1, Chen Q1, Dong Y3.Author information 1Beijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, PR China.2Institute of Food Safety, Chinese Academy of Inspection and Quarantine, Beijing 100123, PR China.3Beijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, PR China. Electronic address: yydong@mail.buct.edu.cn.AbstractTetracycline (TC) is widely used for prevention and control of animal diseases for its broad spectrum antimicrobial activity and low cost, but its abuse can seriously affect human health and may result in trade loss. Thus there is an imperative need to develop high-performing analytical technique for TC detection. In this study, we developed a biosensor based on an indirect competitive enzyme-linked aptamer assay (ic-ELAA). A 76mer single-stranded DNA (ssDNA) aptamer, selected by Systematic Evolution of Ligands by Exponential Enrichment (SELEX), was applied for the recognition and detection of TC in honey. The limit of detection was 9.6×10(-3)ng/mL with a linear working range from 0.01 to 100ng/mL toward TC in honey, and a mean recovery rate of 93.23% in TC-spiked honey was obtained. This aptasensor can be applied to detect TC residue in food with high sensitivity and simplicity, and it is prospective to develop useful ELAA Kits for TC determination in food.
- Biosensors & bioelectronics.Biosens Bioelectron.2014 Jul 15;57:192-8. doi: 10.1016/j.bios.2014.02.032. Epub 2014 Feb 19.
- Tetracycline (TC) is widely used for prevention and control of animal diseases for its broad spectrum antimicrobial activity and low cost, but its abuse can seriously affect human health and may result in trade loss. Thus there is an imperative need to develop high-performing analytical technique fo
- PMID 24583691
- A novel formulation of thiamine dilaurylsulphate and its preservative effect on apple juice and sterilised milk.
- Wei L1, Cheng J1, Meng Y2, Ren Y1, Deng H1, Guo Y1.Author information 1College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an 710062, PR China.2College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an 710062, PR China. Electronic address: mengyonghong@snnu.edu.cn.AbstractThiamine dilaurylsulphate (TLS), synthesised by a new method, was developed for a formulation with a wide antimicrobial spectrum and evaluated in apple juice and milk. The result of a disc diffusion method showed that TLS, which was synthesised from sodium lauryl sulphate and thiamine hydrochloride, had strong growth-inhibitory effects on Gram-positive bacteria, yeasts, and moulds, but had weak inhibitory effects on Gram-negative bacteria such as Escherichia coli. Moreover, the TLS antibacterial spectrum could be broadened to all microbes by formulation with organic acids, such as gluconic acid or acetic acid, since organic acids have synergistic effects on TLS bacteriostasis. Compared to TLS, the formulation had a better preservation in milk (pH 6.64) by viable microbial counting, although the antibacterial effect of the formulation with TLS showed no significant difference in apple juice (pH 3.98). Therefore, the TLS formulation has wide application and better potential, as a preservative, to enhance food safety.
- Food chemistry.Food Chem.2014 Jun 1;152:415-22. doi: 10.1016/j.foodchem.2013.11.159. Epub 2013 Dec 4.
- Thiamine dilaurylsulphate (TLS), synthesised by a new method, was developed for a formulation with a wide antimicrobial spectrum and evaluated in apple juice and milk. The result of a disc diffusion method showed that TLS, which was synthesised from sodium lauryl sulphate and thiamine hydrochloride,
- PMID 24444956
- Expression of cathelicidins mRNA in the goat mammary gland and effect of the intramammary infusion of lipopolysaccharide on milk cathelicidin-2 concentration.
- Zhang GW1, Lai SJ2, Yoshimura Y3, Isobe N4.Author information 1Graduate School of Biosphere Science, Hiroshima University, Higashi-Hiroshima 739-8528, Japan; Institute of Animal Genetics and Breeding, Sichuan Agricultural University, Ya'an, Sichuan 625014, PR China.2Institute of Animal Genetics and Breeding, Sichuan Agricultural University, Ya'an, Sichuan 625014, PR China.3Graduate School of Biosphere Science, Hiroshima University, Higashi-Hiroshima 739-8528, Japan.4Graduate School of Biosphere Science, Hiroshima University, Higashi-Hiroshima 739-8528, Japan. Electronic address: niso@hiroshima-u.ac.jp.AbstractCathelicidins are a family of antimicrobial peptides found in neutrophils and the epithelium that have broad-spectrum activity against bacteria. This study aimed to investigative the mRNA expression of cathelicidins and protein localization of cathelicidin-2 in the goat mammary gland and its secretion into milk. The mRNA expression of cathelicidins was examined in different regions of the mammary gland by reverse transcription PCR. A cathelicidin-2 antibody was raised in rabbits by immunization with a synthetic cathelicidin-2 peptide consisting of 17 amino acids. The protein localization of cathelicidin-2 was investigated in the mammary gland by immunohistochemistry. Skim milk was collected before (0h) and 2, 4, 8, 12, and 24h after the intramammary infusion of lipopolysaccharide and saline, and the concentration of cathelicidin-2 was examined by an enzyme immunoassay. The mRNAs of cathelicidin-1, 2, 3, 6, and 7 were expressed in both the teat and deep region of the mammary gland from healthy and mastitic goats. Immunoreactive cathelicidin-2 was not localized in the epithelial cells of the teat skin, teat cistern, or mammary alveoli, whereas it was localized in polymorphonuclear cells in the mammary gland and those collected from the blood and milk. Cathelicidin-2 was detected in skim milk by Western blotting. The concentration of cathelicidin-2 in milk increased 4h after the intramammary infusion of lipopolysaccharide. These results suggest that cathelicidin-2 is expressed in polymorphonuclear cells and is secreted into milk in goat.
- Veterinary microbiology.Vet Microbiol.2014 May 14;170(1-2):125-34. doi: 10.1016/j.vetmic.2014.01.029. Epub 2014 Feb 7.
- Cathelicidins are a family of antimicrobial peptides found in neutrophils and the epithelium that have broad-spectrum activity against bacteria. This study aimed to investigative the mRNA expression of cathelicidins and protein localization of cathelicidin-2 in the goat mammary gland and its secreti
- PMID 24572177
Japanese Journal
- 九州山口地区における基質拡張型βラクタマーゼ産生菌の検出状況と抗菌薬使用状況に関する合同調査
- 室 高広,北原 隆志,伊東 弘樹 [他]
- 日本環境感染学会誌 = Japanese journal of environmental infecions 29(1), 32-40, 2014
- NAID 40019974990
- 熊本県下8医療施設で1年間に分離されたMRSAを除く主要耐性菌の動向調査
- 正木 孝幸,大隈 雅紀,永田 邦昭 [他]
- 感染症学雑誌 = The journal of Japanese the Association for Infectious Diseases 87(6), 732-738, 2013-11
- NAID 40019903583
- 岐阜県及び愛知県下において分離された基質特異性拡張型β-ラクタマーゼ産生株に対する各種抗菌薬の抗菌活性サーベイランス
- 中川 哲志,久田 晴美,野村 伸彦 [他]
- The Japanese journal of antibiotics 66(5), 251-264, 2013-10
- NAID 40019845724
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★リンクテーブル★
| リンク元 | 「抗菌スペクトル」 |
| 関連記事 | 「antimicrobial」「antimicrobials」「spectrum」 |
「抗菌スペクトル」
- 英
- 関
「antimicrobial」
- adj.
- 抗菌の
- n.
- 関
- anti-bacterial agent、antibacterial、antibacterial agent、antibacterial drug、antibacterials、antibiotic、antibiotics、antimicrobial agent、antimicrobials
「antimicrobials」
- np.
- 関
- anti-bacterial agent、antibacterial、antibacterial agent、antibacterial drug、antibacterials、antibiotic、antibiotics、antimicrobial、antimicrobial agent
「spectrum」
- n.