WordNet

any compound that contains water of crystallization
become hydrated and combine with water
cause to be hydrated; add water or moisture to; "hydrate your skin"
supply water or liquid to in order to maintain a healthy balance; "the bicyclists must be hydrated frequently"
a silvery soft waxy metallic element of the alkali metal group; occurs abundantly in natural compounds (especially in salt water); burns with a yellow flame and reacts violently in water; occurs in sea water and in the mineral halite (rock salt) (同)Na, atomic number 11
small tubular solitary freshwater hydrozoan polyp
trouble that cannot be overcome by a single effort because of its many aspects or its persistent and pervasive quality; "we may be facing a hydra that defies any easy solution"
a tablet (trade name Fosamax) prescribed to prevent or treat osteoporosis in women after menopause (同)Fosamax

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1. HIV感染患者における骨およびカルシウム異常 bone and calcium disorders in hiv infected patients
2. 閉経後女性における骨粗鬆症に対するビスホスホネート投与 the use of bisphosphonates in postmenopausal women with osteoporosis
3. ステロイド誘発性骨粗鬆症の予防および治療 prevention and treatment of glucocorticoid induced osteoporosis
4. 骨パジェット病の治療 treatment of paget disease of bone
5. 骨形成不全症：管理および予後 osteogenesis imperfecta management and prognosis

[New development in bisphosphonate treatment. Review of effect on bone metabolism by minodronic acid in primary osteoporosis].

Fukunaga M.SourceKawasaki Medical School, Department of Nuclear Medicine, Japan.
Clinical calcium.Clin Calcium.2009 Jan;19(1):63-73.
Minodronic acid hydrate is a novel bisphosphonate with stronger anti-resorptive effects, compared to the other existing bisphosphonates. We performed additional analyses of phase III clinical trial and compared the effect of minodronic acid hydrate on bone turnover markers with those of alendronate
PMID 19122266

[Therapeutic agents for disorders of bone and calcium metabolism: Minodronic acid hydrate].

Miki T, Minamide T.SourceOno Pharmaceutical Co., Ltd., Clinical Planning III Development Planning.
Clinical calcium.Clin Calcium.2007 Jan;17(1):18-22.
Minodronic acid hydrate is one of the new-generation bisphosphonates containing nitrogen. This drug has an inhibitory effect on bone resorption by suppressing the osteoclastic function, and it is being developed as a therapeutic drug of osteoporosis. In non-clinical study, the drug has an inhibitory
PMID 17211089

Use of FDG PET to Evaluate Hyperbaric Oxygen Therapy for Bisphosphonate-Related Osteonecrosis of the Jaw

Yamazaki Yutaka,Kitagawa Yoshimasa,Hata Hironobu,Abe Takahiro,Murai Chika,Shiga Tohru,Tamaki Nagara
Clinical Nuclear Medicine 35(8), 590-591, 2010-08
… He had taken oral alendronate sodium hydrate and prednisolone for osteoporosis for five years. …
NAID 120003631379

井手若奈,飯嶋久志,宇野弘展,木村英晃,久保田洋子,澤田愛子,平井政彦,吉川真由美,鈴木久夫,石野良和,安藤秀人
医療薬学 34(5), 455-460, 2008-05-10
… Pharmacies questioned patients who had been prescribed bisphosphonates such as etidronate disodium, alendronate sodium hydrate and sodium risedronate hydrate, or raloxifene hydrochloride with regard to compliance and post-dosing events. …
NAID 110006664361