急性混合性白血病、急性混合型白血病
- 関
 
- mixed-cell leukemia
 
WordNet
- of critical importance and consequence; "an acute (or critical) lack of research funds"
 
- having or demonstrating ability to recognize or draw fine distinctions; "an acute observer of politics and politicians"; "incisive comments"; "icy knifelike reasoning"; "as sharp and incisive as the stroke of a fang"; "penetrating insight"; "frequent penetrative observations" (同)discriminating, incisive, keen, knifelike, penetrating, penetrative, piercing, sharp
 
- extremely sharp or intense; "acute pain"; "felt acute annoyance"; "intense itching and burning" (同)intense
 
- having or experiencing a rapid onset and short but severe course; "acute appendicitis"; "the acute phase of the illness"; "acute patients"
 
- of an angle; less than 90 degrees
 
- malignant neoplasm of blood-forming tissues; characterized by abnormal proliferation of leukocytes; one of the four major types of cancer (同)leukaemia, leucaemia, cancer of the blood
 
PrepTutorEJDIC
- (先の)『鋭い』,とがった / (痛み・感情などが)『激しい』,強い / (知力・感覚などが)『鋭い』,鋭敏な / (事態が)重大な / (病気が)急性の / (音が)高い,鋭い / 鋭角の
 
- 白血病
 
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/11/02 21:26:26」(JST)
[Wiki en表示]
| Acute biphenotypic leukemia | 
| Classification and external resources | 
| ICD-O: | 
9805/3 | 
| MeSH | 
D015456 | 
Acute biphenotypic leukaemia is a form of leukaemia where the lineage is of both lymphoid and myeloid origin.[1][2]
It is a subtype of "leukemia of ambiguous lineage".[3]
References[edit]
- ^ Matutes E, Morilla R, Farahat N, et al. (1997). "Definition of acute biphenotypic leukemia". Haematologica 82 (1): 64–6. PMID 9107085. 
 
- ^ Han X, Bueso-Ramos CE (April 2007). "Precursor T-cell acute lymphoblastic leukemia/lymphoblastic lymphoma and acute biphenotypic leukemias". Am. J. Clin. Pathol. 127 (4): 528–44. doi:10.1309/2QE3A6EKQ8UYDYRC. PMID 17369128. 
 
- ^ Frater JL, Yaseen NR, Peterson LC, Tallman MS, Goolsby CL (March 2003). "Biphenotypic acute leukemia with coexpression of CD79a and markers of myeloid lineage". Arch. Pathol. Lab. Med. 127 (3): 356–9. doi:10.1043/0003-9985(2003)127<0356:BALWCO>2.0.CO;2. PMID 12653584. 
 
 
| 
 Hematological malignancy/leukemia histology (ICD-O 9590–9989, C81–C96, 200–208) 
Lymphoid/Lymphoproliferative, Lymphomas/Lymphoid leukemias (9590–9739, 9800–9839) 
 | 
 
 | 
 
B cell 
(lymphoma, 
leukemia) 
(most CD19
 
 
 | 
| 
 By development/ 
marker 
 | 
| 
 TdT+ 
 | 
- ALL (Precursor B acute lymphoblastic leukemia/lymphoma)
 
 
 
 | 
 
 | 
 
| 
 CD5+ 
 | 
 mantle zone (Mantle cell) 
 | 
 
 | 
 
| 
 CD22+ 
 | 
- Prolymphocytic
 
- CD11c+ (Hairy cell leukemia)
 
 
 
 | 
 
 | 
 
| 
 CD79a+ 
 | 
- germinal center/follicular B cell (Follicular
 
- Burkitt's
 
- GCB DLBCL
 
- Primary cutaneous follicular lymphoma)
 
 
 
marginal zone/marginal-zone B cell (Splenic marginal zone
 
- MALT
 
- Nodal marginal zone
 
- Primary cutaneous marginal zone lymphoma)
 
 
 
 | 
 
 | 
 
| 
 RS (CD15+, CD30+) 
 | 
- Classic Hodgkin's lymphoma (Nodular sclerosis)
 
- CD20+ (Nodular lymphocyte predominant Hodgkin's lymphoma)
 
 
 
 | 
 
 | 
 
| 
 PCDs/PP 
(CD38+/CD138+) 
 | 
- see immunoproliferative immunoglobulin disorders
 
 
 
 | 
 
 
 | 
 
 | 
 
| 
 By infection 
 | 
- KSHV (Primary effusion)
 
- EBV (Lymphomatoid granulomatosis
 
- Post-transplant lymphoproliferative disorder)
 
- HIV (AIDS-related lymphoma)
 
- Helicobacter pylori (MALT lymphoma)
 
 
 
 | 
 
 | 
 
| 
 Cutaneous 
 | 
- Diffuse large B-cell lymphoma
 
- Intravascular large B-cell lymphoma
 
- Primary cutaneous marginal zone lymphoma
 
- Primary cutaneous immunocytoma
 
- Plasmacytoma
 
- Plasmacytosis
 
- Primary cutaneous follicular lymphoma
 
 
 
 | 
 
 
 | 
 
 | 
 
| 
 T/NK 
 | 
T cell 
(lymphoma, 
leukemia) 
(most CD3
 
 
 | 
| 
 By development/ 
marker 
 | 
- TdT+: ALL (Precursor T acute lymphoblastic leukemia/lymphoma)
 
 
- prolymphocyte (Prolymphocytic)
 
 
- CD30+ (Anaplastic large-cell lymphoma
 
- Lymphomatoid papulosis type A)
 
 
 
 | 
 
 | 
 
| 
 Cutaneous 
 | 
| 
 MF+variants 
 | 
- indolent: Mycosis fungoides
 
- Pagetoid reticulosis
 
- Granulomatous slack skin
  
 
aggressive: Sézary's disease 
- Adult T-cell leukemia/lymphoma
 
 
 
 | 
 
 | 
 
| 
 Non-MF 
 | 
- CD30-: Non-mycosis fungoides CD30− cutaneous large T-cell lymphoma
 
- Pleomorphic T-cell lymphoma
 
- Lymphomatoid papulosis type B
 
 
CD30+: CD30+ cutaneous T-cell lymphoma 
- Secondary cutaneous CD30+ large cell lymphoma
 
- Lymphomatoid papulosis type A
 
 
 
 | 
 
 
 | 
 
 | 
 
| 
 Other peripheral 
 | 
- Hepatosplenic
 
- Angioimmunoblastic
 
- Enteropathy-associated T-cell lymphoma
 
- Peripheral T-cell lymphoma-Not-Otherwise-Specified (Lennert lymphoma)
 
- Subcutaneous T-cell lymphoma
 
 
 
 | 
 
 | 
 
| 
 By infection 
 | 
- HTLV-1 (Adult T-cell leukemia/lymphoma)
 
 
 
 | 
 
 
 | 
 
 | 
 
| 
 NK cell/ 
(most CD56) 
 | 
- Aggressive NK-cell leukemia
 
- Blastic NK cell lymphoma
 
 
 
 | 
 
 | 
 
| 
 T or NK 
 | 
- EBV (Extranodal NK-T-cell lymphoma/Angiocentric lymphoma)
 
- Large granular lymphocytic leukemia
 
 
 
 | 
 
 
 | 
 
 | 
 
| 
 Lymphoid+myeloid 
 | 
- Acute biphenotypic leukaemia
 
 
 
 | 
 
 | 
 
| 
 Lymphocytosis 
 | 
- Lymphoproliferative disorders (X-linked lymphoproliferative disease
 
- Autoimmune lymphoproliferative syndrome)
 
- Leukemoid reaction
 
- Diffuse infiltrative lymphocytosis syndrome
 
 
 
 | 
 
 
 | 
 
 | 
 
| Cutaneous lymphoid hyperplasia | 
- Cutaneous lymphoid hyperplasia
- with bandlike and perivascular patterns
 
- with nodular pattern
 
 
 
- Jessner lymphocytic infiltrate of the skin
 
 
 
 | 
 
 | 
 
| 
 | 
cell/phys/auag/auab/comp, igrc 
 
 | 
 | 
 | 
 
 
 
 | 
 
 
 | 
 
 
 | 
| 
 Myeloid hematological malignancy/leukemia histology (ICD-O 9590–9989, C81–C96, 200–208) 
 | 
 
 | 
 
CFU-GM/ 
and other granulocytes | 
| 
 CFU-GM 
 | 
| 
 Myelocyte 
 | 
AML: Acute myeloblastic leukemia (M0, M1, M2), APL/M3 
MP (Chronic neutrophilic leukemia) 
 
 | 
 
 | 
 
| 
 Monocyte 
 | 
AML (AMoL/M5, Myeloid dendritic cell leukemia) 
CML (Philadelphia chromosome, Accelerated phase chronic myelogenous leukemia) 
 
 | 
 
 | 
 
| 
 Myelomonocyte 
 | 
AML (M4) 
MD-MP (Juvenile myelomonocytic leukemia, Chronic myelomonocytic leukemia) 
 
 | 
 
 | 
 
| 
 Other 
 | 
 Histiocytosis 
 | 
 
 
 | 
 
 | 
 
| 
 CFU-Baso 
 | 
 AML (Acute basophilic) 
 | 
 
 | 
 
| 
 CFU-Eos 
 | 
AML (Acute eosinophilic) 
MP (Chronic eosinophilic leukemia/Hypereosinophilic syndrome) 
 
 | 
 
 
 | 
 
 | 
 
| MEP | 
| 
 CFU-Meg 
 | 
AML (AMKL/M7) 
MP (Essential thrombocytosis) 
 
 | 
 
 | 
 
| 
 CFU-E 
 | 
AML (Erythroleukemia/M6) 
MP (Polycythemia vera) 
MD (Refractory anemia, Refractory anemia with excess of blasts, Chromosome 5q deletion syndrome, Sideroblastic anemia, Paroxysmal nocturnal hemoglobinuria, Refractory cytopenia with multilineage dysplasia) 
 
 | 
 
 
 | 
 
 | 
 
| CFU-Mast | 
Mastocytoma (Mast cell leukemia, Mast cell sarcoma, Systemic mastocytosis) 
Mastocytosis: Diffuse cutaneous mastocytosis ·  Erythrodermic mastocytosis ·  Generalized eruption of cutaneous mastocytosis (adult type) ·  Generalized eruption of cutaneous mastocytosis (childhood type) ·  Mast cell sarcoma ·  Solitary mastocytoma ·  Systemic mastocytosis ·  Xanthelasmoidal mastocytosis 
 
 | 
 
 | 
 
| Multiple/unknown | 
 AML (Acute panmyelosis with myelofibrosis, Myeloid sarcoma) ·  MP (Myelofibrosis) ·  Acute biphenotypic leukaemia 
 | 
 
 | 
 
| 
 | 
cell/phys (coag, heme, immu, gran), csfs 
 
 | 
rbmg/mogr/tumr/hist, sysi/epon, btst 
 
 | 
drug (B1/2/3+5+6), btst, trns 
 
 | 
 
 
 
 | 
 
 
 | 
 
 
 | 
 
UpToDate Contents
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English Journal
- Generation and characterization of bioluminescent xenograft mouse models             of MLL-related acute leukemias and in vivo evaluation of luciferase-targeting             siRNA nanoparticles.
 
- Fazzina R, Lombardini L, Mezzanotte L, Roda A, Hrelia P, Pession A, Tonelli R.SourceDepartment of Pediatric Oncology and Hematology, Sant' Orsola                     Hospital, University of Bologna, Bologna, Italy.
 
- International journal of oncology.Int J Oncol.2012 Aug;41(2):621-8. doi: 10.3892/ijo.2012.1504. Epub  2012 May 31.
 
- Chromosomal translocations involving the MLL gene on 11q23 present frequent             abnormalities in pediatric, adult and therapy-related acute leukemias, and are             generally associated with aggressive disease and poor prognosis. Here, we report             bioluminescent acute leukemi
 
- PMID 22665135
 
- The mixed lineage leukemia (MLL) fusion-associated gene AF4 promotes CD133 transcription.
 
- Mak AB, Nixon AM, Moffat J.SourceDonnelley Centre and Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada.
 
- Cancer research.Cancer Res.2012 Apr 15;72(8):1929-34. Epub  2012 Feb 14.
 
- The AC133 epitope has been used as a marker for both normal and cancer stem cells from multiple tissue lineages. To identify transcription factors that regulate CD133 expression, we conducted parallel large-scale RNA interference screens in Caco-2 cancer cells that endogenously express CD133 and in 
 
- PMID 22337994
 
Japanese Journal
- WHO分類2008に基づく急性混合性白血病の臨床像の解析
 
- 臨牀指針 汎血球減少を初発症状に診断された急性混合性白血病(Biphenotypic Acute leukemia)の1例
 
Related Links
- 1. Haematologica. 1997 Jan-Feb;82(1):64-6. Definition of acute biphenotypic leukemia. Matutes E(1), Morilla R, Farahat N, Carbonell F, Swansbury J, Dyer M, Catovsky D. Author information: (1)Academic Department of ...
 
- Symptoms of Acute biphenotypic leukemia The list of signs and symptoms mentioned in various sources for Acute biphenotypic leukemia includes the 11 symptoms listed below: Panctyopenia Reduced appetite Enlarged liver Fever
 
★リンクテーブル★
  [★]
- 英
 
- acute biphenotypic leukemia
 
- 同
 
- 急性混合型白血病
 
[show details]
  [★]
- 英
 
- acute biphenotypic leukemia
 
- 関
 
- 混合細胞型白血病、急性混合性白血病
 
  [★]
混合細胞型白血病
- 関
 
- acute biphenotypic leukemia
 
  [★]
- (疾患)急性の、急性型の、急性的な。(形状が)鋭い、鋭角の。(感覚、才知などが)鋭い。明敏な、鋭い眼識のある。
 
- 関
 
- acutely、quick、sharp