Wolffian duct

ウォルフ管、Wolffian管、中腎管

WordNet

1. a continuous tube formed by a row of elongated cells lacking intervening end walls
2. an enclosed conduit for a fluid
3. a bodily passage or tube lined with epithelial cells and conveying a secretion or other substance; "the tear duct was obstructed"; "the alimentary canal"; "poison is released through a channel in the snakes fangs" (同)epithelial duct, canal, channel
4. minute rootless aquatic herbs having globular fronds floating on or near the water surface and bearing one flower per frond (同)genus Wolffia

PrepTutorEJDIC

1. 送水管;(建物・船などの)通気管;(地下ケーブルなどの)ダクト / (体液を運ぶ)導管,(植物が水・空気を運ぶ)導管

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/04/18 08:08:51」(JST)

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[Wiki en表示]

Mesonephric duct
Urogenital sinus of female human embryo of eight and a half to nine weeks old.
Transverse section of a chick embryo of forty-five hours' incubation.
Latin	ductus mesonephricus; ductus Wolffi
Gray's	subject #252 1205
Carnegie stage	11
Days	28
Precursor	intermediate mesoderm
Gives rise to	vas deferens, seminal vesicles, epididymis
Code	TE E5.6.2.0.0.0.4

The mesonephric duct (also known as Wolffian duct, archinephric duct, Leydig's duct and nephric duct) is a paired organ found in mammals including humans during embryogenesis.

It connects the primitive kidney Wolffian body (or mesonephros) to the cloaca and serves as the anlage for certain male reproductive organs.

Development

Wolffian duct (red) degenerates in females (middle image) and develops in males (bottom).

In both the male and the female the Wolffian duct develops into the trigone of urinary bladder, a part of the bladder wall. However, further development differentiates between the sexes in the development of the urinary and reproductive organs.

Male development

In a male, it develops into a system of connected organs between the efferent ducts of the testis and the prostate, namely the epididymis, the vas deferens, and the seminal vesicle. The prostate forms from the urogenital sinus and the efferent ducts form from the mesonephric tubules.

For this it is critical that the ducts are exposed to testosterone during embryogenesis. Testosterone binds to and activates androgen receptor, affecting intracellular signals and modifying the expression of numerous genes..

In the mature male, the function of this system is to store and mature sperm, and provide accessory semen fluid.

Female development

In the female, in the absence of testosterone support, the Wolffian duct regresses, and inclusions may persist. The epoophoron and Skene's glands may be present. Also, lateral to the wall of the vagina a Gartner's duct or cyst could develop as a remnant.

The derivatives of the Mesonephric duct can be remembered using the mnemonic, "Gardener's SEED" for Gartner's duct, Seminal vesicles, Epididymis, Ejaculatory duct and Ductus deferens.

History

It is named after Caspar Friedrich Wolff who described the mesonephros and its ducts in his dissertation in 1759.

Additional images

• Diagram of a transverse section, showing the mode of formation of the amnion in the chick.

• Reconstruction of a human embryo of 17 mm.

• Cloaca of human embryo from twenty-five to twenty-seven days old.

• Broad ligament of adult, showing epoophoron.

• Transverse section of human embryo eight and a half to nine weeks old.

• Tail end of human embryo twenty-five to twenty-nine days old.

• Tail end of human embryo thirty-two to thirty-three days old.

• Tail end of human embryo; from eight and a half to nine weeks old.

• Primitive kidney and bladder, from a reconstruction.

See also

• Fetal genital development
• List of homologues of the human reproductive system
• Masculinization
• Müllerian duct
• Sexual differentiation

References

External links

• Mnemonic at medicalmnemonics.com 1266
• How the Body Works / Sex Development / Sexual Differentiation / Duct Differentiation - The Hospital for Sick Children (GTA - Toronto, Ontario, Canada)

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. 正常な性的発育 normal sexual development
• 2. 後部尿道弁の臨床症状および診断 clinical presentation and diagnosis of posterior urethral valves
• 3. 非定型生殖器（性分化疾患）を有する乳児の評価 evaluation of the infant with atypical genitalia disorder of sex development
• 4. アンドロゲン受容体障害の病因および臨床症状 pathogenesis and clinical manifestations of disorders of androgen action
• 5. 先天性膣奇形の診断およびマネージメント diagnosis and management of congenital anomalies of the vagina

English Journal

• Dynamic expression of Tbx2 subfamily genes in development of the mouse reproductive system.

• Douglas NC, Heng K, Sauer MV, Papaioannou VE.SourceDepartment of Obstetrics and Gynecology, Columbia University Medical Center, New York, New York. nd2058@columbia.edu.
• Developmental dynamics : an official publication of the American Association of Anatomists.Dev Dyn.2012 Feb;241(2):365-75. doi: 10.1002/dvdy.23710. Epub 2011 Dec 16.
• Background: Tbx2, Tbx3, Tbx4, and Tbx5, members of the Tbx2 subfamily of T-box transcription factor genes, are important for many aspects of embryonic development and mutations in some human TBX2 subfamily genes cause developmental syndromes. In addition, TBX2 and TBX3 are overexpressed in a variety
• PMID 22223620

• Ureteric Morphogenesis Requires Fgfr1 and Fgfr2/Frs2α Signaling in the Metanephric Mesenchyme.

• Sims-Lucas S, Di Giovanni V, Schaefer C, Cusack B, Eswarakumar VP, Bates CM.Source*Rangos Research Center, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania;
• Journal of the American Society of Nephrology : JASN.J Am Soc Nephrol.2012 Jan 26. [Epub ahead of print]
• Conditional deletion of fibroblast growth factor receptors (Fgfrs) 1 and 2 in the metanephric mesenchyme (MM) of mice leads to a virtual absence of MM and unbranched ureteric buds that are occasionally duplex. Deletion of Fgfr2 in the MM leads to kidneys with cranially displaced ureteric buds along
• PMID 22282599

• Molecular characteristics and alterations during early development of the human vagina.

• Fritsch H, Richter E, Adam N.SourceDivision of Clinical and Functional Anatomy, Department of Anatomy, Histology and Embryology, Innsbruck Medical University, Innsbruck, Austria.
• Journal of anatomy.J Anat.2012 Jan 19. doi: 10.1111/j.1469-7580.2011.01472.x. [Epub ahead of print]
• Unresolved questions remain concerning the derivation of the vagina with respect to the relative contributions from the Müllerian ducts, the urogenital sinus, and the Wolffian ducts. Recent molecular and cellular studies in rodents have opened up a large gap between the level of understanding of va
• PMID 22256858

Japanese Journal

• 症例報告 Wolffian Tumorの2例

• 真壁 健,平尾 薫丸,井口 蓉子 [他]
• 東京産科婦人科学会会誌 63(3), 417-422, 2014-07
• NAID 40020185889

• Transgenesis of the Wolffian duct visualizes dynamic behavior of cells undergoing tubulogenesis in vivo

• Atsuta Yuji,Tadokoro Ryosuke,Saito Daisuke [他]
• Development, growth & differentiation 55(4), 579-590, 2013-05
• NAID 40019735246

• A case of Gartner's duct cyst arising from the cervix resected by laparoscopic surgery

• 米田 由香里,和田 俊朗,福島 和子,鮫島 浩
• 日本産科婦人科内視鏡学会雑誌 27(2), 429-432, 2011
• …   Gartner's duct cysts are dilated Wolffian duct remnants commonly found in the lateral part of the vagina. … We report a case of Gartner's duct cyst arising from the cervix, which was resected laparoscopically. … The cyst was diagnosed as a Gartner's duct cyst arising from the cervix. …
• NAID 130002049867

Related Links

• Wolffian Duct | Definition of Wolffian duct by Merriam-Webster

:the duct of the mesonephros that persists in the female chiefly as part of a vestigial organ and in the male as the duct system leaving the testis and including ... Seen and Heard What made you want to look up Wolffian duct? Please ...

• Wolffian duct | definition of wolffian duct by Medical dictionary

mes·o·neph·ric duct a duct in the embryo draining the mesonephric tubules in the mesonephros; in the male, it becomes the ductus deferens; in the female, it becomes vestigial. See also: longitudinal duct of epoophoron. Synonym ...

Related Pictures

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★リンクテーブル★

リンク元	「中腎管」「ガートナー管」「Wolffian管」
関連記事	「duct」

「中腎管」

　　[★]

英

mesonephric duct (Z)

ラ

ductus mesonephricus

同

Wolffian duct wolff管、ウォルフ管

関

中腎傍管 ミュラー管

発生学

• 男性：テストステロンにより分化する。精巣輸出管、精巣上体、精管、精嚢となる。
• 女性：ウォルフ管の大部分は失われる。卵巣間膜に卵巣上体、卵巣傍体が、膣壁の外部にゲルトネル管嚢腫が痕跡的器官として残る。

「ガートナー管」

　　[★]

英

Gartner duct (Z), Gartner's duct

同

Gartner管

関

Wolffian duct

[show details]

ガートナー Gartner : 約 164,000 件
ガルトナー Gartner : 約 395 件
ガートナー管 : 約 77 件
ガルトナー管 : 48 件
ガートナー嚢胞 : 約 11 件
ガルトナー嚢胞 : 13 件

• 卵巣上体縦管

「Wolffian管」

　　[★]

英

Wolffian duct

関

ウォルフ管

「duct」

　　[★]

• n.

• 管、(植物)導管

関

canal、conduit、ductal、ductus、meatus、pipe、tubal、tube、vas、vessel