WordNet

the 20th letter of the Roman alphabet (同)t
an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
(Norse mythology) god of war and strife and son of Odin; identified with Anglo-Saxon Tiu (同)Tyrr
the basic unit of money in Papua New Guinea

PrepTutorEJDIC

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

Gastrointestinal hormones stimulate growth of Foregut Neuroendocrine Tumors by transactivating the EGF receptor.

Di Florio A, Sancho V, Moreno P, Delle Fave G, Jensen RT.SourceDigestive Diseases Branch, NIDDK, National Institutes of Health, Bethesda, MD 20892-1804, USA.
Biochimica et biophysica acta.Biochim Biophys Acta.2013 Mar;1833(3):573-82. doi: 10.1016/j.bbamcr.2012.11.021. Epub 2012 Dec 4.
Foregut neuroendocrine tumors [NETs] usually pursuit a benign course, but some show aggressive behavior. The treatment of patients with advanced NETs is marginally effective and new approaches are needed. In other tumors, transactivation of the EGF receptor (EGFR) by growth factors, gastrointestinal
PMID 23220008

Protein Tyrosine Phosphatase with Proline-Glutamine-Serine-Threonine-Rich Motifs Negatively Regulates TLR-Triggered Innate Responses by Selectively Inhibiting IκB Kinase β/NF-κB Activation.

Zhang P, Liu X, Li Y, Zhu X, Zhan Z, Meng J, Li N, Cao X.SourceNational Key Laboratory of Medical Immunology, Second Military Medical University, Shanghai 200433, China;
Journal of immunology (Baltimore, Md. : 1950).J Immunol.2013 Feb 15;190(4):1685-94. doi: 10.4049/jimmunol.1202384. Epub 2013 Jan 7.
TLRs are essential for sensing the invading pathogens and initiating protective immune responses. However, aberrant activation of TLR-triggered inflammatory innate responses leads to the inflammatory disorders and autoimmune diseases. The molecular mechanisms that fine-tune TLR responses remain to b
PMID 23296707

Activation of JAK-STAT3 signaling pathway in chronic subdural hematoma outer membranes.

Osuka K, Watanabe Y, Usuda N, Atsuzawa K, Shima H, Takeuchi M, Yasuda M, Takayasu M.SourceDepartment of Neurological Surgery, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan.
Neuroscience letters.Neurosci Lett.2013 Feb 8;534:166-70. doi: 10.1016/j.neulet.2012.11.011. Epub 2012 Nov 19.
Chronic subdural hematoma (CSDH) is an inflammatory disease, the mechanism of which still remains to be elucidated. Interleukin-6 (IL-6), one of the inflammatory cytokines regulating janus kinase (JAK)-signal transducer and activator of transcription (STAT) signaling pathway, is expressed in human C
PMID 23174178

ROCK2 regulates bFGF-induced proliferation of SH-SY5Y cells through GSK-3β and β-catenin pathway

Boku Shuken,Nakagawa Shin,Toda Hiroyuki,Kato Akiko,Takamura Naoki,Omiya Yuki,Inoue Takeshi,Koyama Tsukasa
Brain Research 1492, 7-17, 2013-01-25
… Results demonstrate that bFGF is necessary for the proliferation of neural precursor cells and that the glycogen synthase kinase-3β (GSK-3β) and β-catenin pathway plays a role in it. … To elucidate that mechanism, we investigated the role of Rho-associated coiled-coil kinase (ROCK) in bFGF-induced proliferation using SH-SY5Y cells as a model of neural precursor-like cells. …
NAID 120005228253

浅岡洋一
比較生理生化学 30(2), 59-67, 2013
… c-Jun N-terminal kinase（JNK）シグナル伝達経路は，細胞外からの様々なストレス刺激や発生プログラムなどの内因性シグナルを細胞核へ的確に伝達するための主要なシステムの１つである。 …
NAID 130003369134

Class-IA Phosphoinositide 3-Kinase p110β Triggers GPCR-Induced Superoxide Production in p110γ-Deficient Murine Neutrophils

Nigorikawa Kiyomi,Hazeki Kaoru,Kumazawa Takashi [他],Itoh Yuhta,Hoshi Megumi,Hazeki Osamu
Journal of Pharmacological Sciences 120(4), 270-279, 2012
… Studies with knockout mice have indicated that the only isoform of phosphoinositide 3-kinase (PI3K) functioning in the oxidative burst of mouse neutrophils in response to heterotrimeric guanine nucleotide-binding protein–coupled receptor (GPCR) agonists is a class-IB PI3K, p110γ. … Even the unprimed cells, which show no response to fMLP, produce a significant amount of superoxide, when an effective agonist of the mouse-type fMLP receptors, Trp-Lys-Tyr-Met-Val-D-Met, is used to stimulate the cells. …
NAID 130002505873