フィラデルフィア陽性骨髄性白血病
- 関
- chronic granulocytic leukemia、chronic myelocytic leukemia、chronic myelogenous leukemia、chronic myeloid leukemia、Philadelphia-negative myeloid leukemia
WordNet
- reckoned, situated or tending in the direction which naturally or arbitrarily is taken to indicate increase or progress or onward motion; "positive increase in graduating students"
- a film showing a photographic image whose tones correspond to those of the original subject
- the primary form of an adjective or adverb; denotes a quality without qualification, comparison, or relation to increase or diminution (同)positive degree
- indicating existence or presence of a suspected condition or pathogen; "a positive pregnancy test" (同)confirming
- having a positive charge; "protons are positive" (同)electropositive, positively charged
- formally laid down or imposed; "positive laws" (同)prescribed
- characterized by or displaying affirmation or acceptance or certainty etc.; "a positive attitude"; "the reviews were all positive"; "a positive benefit"; "a positive demand"
- greater than zero; "positive numbers"
- the largest city in Pennsylvania; located in the southeastern part of the state on the Delaware river; site of Independence Hall where the Declaration of Independence and the Constitution were signed; site of the University of Pennsylvania (同)City of Brotherly Love
- of or relating to the spinal cord
- of or relating to bone marrow
- malignant neoplasm of blood-forming tissues; characterized by abnormal proliferation of leukocytes; one of the four major types of cancer (同)leukaemia, leucaemia, cancer of the blood
PrepTutorEJDIC
- 『肯定した,同意の』 / 『実際的な,』積極的な,建設的な / 《補語にのみ用いて》『確信のある』,自信のある / (事が)疑問の余地がない,明確な;(言葉が)はっきりした / 《名詞の前にのみ用いて》《話》全くの,文字どおりの / (生体の反応が)陽性の / (数が)正の,プラスの;(気電が)陽の;(写真で)陽画の / (形容詞・副詞の比較変化で)原級の / 明確(明白)なもの / (形容詞・副詞の)原級 / (写真の)陽画,ポジ / (数学で)正数
- 『フィラデルフィア』(米国Pennsylvania州の大都市;1776年7月4日,米国独立宣言の行われた所)
- 白血病
UpToDate Contents
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English Journal
- Ponatinib is a potent inhibitor of wild-type and drug-resistant gatekeeper mutant RET kinase.
- Mologni L, Redaelli S, Morandi A, Plaza-Menacho I, Gambacorti-Passerini C.SourceDept. of Health Sciences, University of Milano-Bicocca, via Cadore 48, 20900 Monza, Italy. Electronic address: luca.mologni@unimib.it.
- Molecular and cellular endocrinology.Mol Cell Endocrinol.2013 Sep 5;377(1-2):1-6. doi: 10.1016/j.mce.2013.06.025. Epub 2013 Jun 27.
- RET kinase is aberrantly activated in thyroid cancers and in rare cases of lung and colon cancer, and has been validated as a molecular target in these tumors. Vandetanib was recently approved for the treatment of medullary thyroid cancer. However, vandetanib is ineffective in vitro against RET muta
- PMID 23811235
- Alantolactone induces apoptosis in chronic myelogenous leukemia sensitive or resistant to imatinib through NF-κB inhibition and Bcr/Abl protein deletion.
- Wei W, Huang H, Zhao S, Liu W, Liu CX, Chen L, Li JM, Wu YL, Yan H.SourceDepartment of Hematology, Rui-Jin Hospital, Shanghai Jiao-Tong University School of Medicine, No. 197, Ruijin Er Road, Shanghai, 200025, China.
- Apoptosis : an international journal on programmed cell death.Apoptosis.2013 Sep;18(9):1060-70. doi: 10.1007/s10495-013-0854-2.
- Alantolactone, an allergenic sesquiterpene lactone, has recently been found to have significant antitumor effects on malignant tumor cells. Here, we investigated the potential effect of alantolactone on Bcr/Abl(+) imatinib-sensitive and -resistant cells. Alantolactone treatment resulted in obvious a
- PMID 23613107
- Effects of ketoconazole on the pharmacokinetics of ponatinib in healthy subjects.
- Narasimhan NI, Dorer DJ, Niland K, Haluska F, Sonnichsen D.SourceARIAD Pharmaceuticals, Inc., Cambridge, MA, USA.
- Journal of clinical pharmacology.J Clin Pharmacol.2013 Sep;53(9):974-81. doi: 10.1002/jcph.109. Epub 2013 Jun 25.
- Ponatinib is a BCR-ABL tyrosine kinase inhibitor (TKI) approved for the treatment of chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia in patients resistant or intolerant to prior TKIs. In vitro studies suggested that metabolism of ponatinib is partially medi
- PMID 23801357
Japanese Journal
- 臍帯血移植後に生着不全となったがPh染色体の消失を認めたPh染色体陽性急性骨髄性白血病
- 浜田 泰子,中村 恭子,田近 賢二 [他],檀 和夫
- 臨床血液 52(2), 58-62, 2011-02-28
- … Philadelphia染色体(Ph)陽性急性骨髄性白血病(Ph+AML)と診断し，imatinib併用化学療法後，骨髄非破壊的臍帯血移植を施行した。 …
- NAID 10029424249
- Can We Distinguish Chronic Myeloid Leukemia Presenting in the Lymphoblastic Phase from de novo Philadelphia-Positive Acute Lymphoid Leukemia?
- イマチニブ時代における小児Ph陽性慢性骨髄性白血病の治療戦略
Related Links
- 3 Feb 2012 ... Philadelphia chromosome-positive leukemias: from basic mechanisms to molecular therapeutics. Ann Intern Med 138 (10): 819-30, 2003. [PUBMED Abstract]; Goldman JM, Melo JV: Chronic myeloid leukemia--advances in ...
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フィラデルフィア陰性骨髄性白血病
- 関
- chronic granulocytic leukemia、chronic myelocytic leukemia、chronic myelogenous leukemia、chronic myeloid leukemia、Philadelphia-positive myeloid leukemia
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- 英
- Philadelphia-positive myeloid leukemia
- 関
- 慢性骨髄性白血病、慢性顆粒球性白血病、フィラデルフィア陰性骨髄性白血病
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- 関
- active、actively、aggressive、offensive、positively、positivity
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- 関
- BM、bone marrow、myelo、myelocytic、myelogenous
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