関: Philadelphia chromosome

WordNet

the 16th letter of the Roman alphabet (同)p
a threadlike strand of DNA in the cell nucleus that carries the genes in a linear order; "humans have 22 chromosome pairs plus two sex chromosomes"

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parking
phosphorusの化学記号
染色体

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1. 慢性骨髄性白血病の分子遺伝学molecular genetics of chronic myeloid leukemia [show details]
…invariably associated with an abnormal chromosome 22 known as the Philadelphia chromosome, often abbreviated as Ph, Ph(1), or Ph¹ . The Philadelphia chromosome t(9;22)(q34;q11) results in the formation …
2. 慢性骨髄性白血病の細胞生物学および分子生物学cellular and molecular biology of chronic myeloid leukemia [show details]
…almost invariably associated an abnormal chromosome 22 known as the Philadelphia chromosome, often abbreviated as Ph, Ph(1), or Ph¹ . The Philadelphia chromosome t(9;22)(q34;q11) results in the formation …
3. 性染色体異常sex chromosome abnormalities [show details]
…the X chromosome with a 45,X karyotype. Other forms of Turner include mosaicism for X chromosome monosomy (eg, 45,X/46,XX) or 45,X/46,XY mosaic with or without a partial deletion of the Y chromosome. The …
4. 成人のフィラデルフィア染色体陰性急性リンパ芽球性白血病／リンパ腫に行う導入療法induction therapy for philadelphia chromosome negative acute lymphoblastic leukemia lymphoma in adults [show details]
…Philadelphia chromosome (Ph+) or its gene fusion product (BCR-ABL1) should be treated with a regimen that incorporates a tyrosine kinase inhibitor, as discussed separately. Philadelphia chromosome (Ph)-like …
5. 成人におけるフィラデルフィア染色体陰性急性リンパ芽球性白血病に対する寛解後療法 post remission therapy for philadelphia chromosome negative acute lymphoblastic leukemia in adults [show details]
…Philadelphia chromosome negative ALL in adults. The following related subjects are presented separately: Induction therapy for ALL in adults. Post-remission therapy for Philadelphia chromosome positive …

English Journal

Targeting bcr-abl Transcripts with siRNAs in an Imatinib-Resistant Chronic Myeloid Leukemia Patient: Challenges and Future Directions.

Koldehoff M.
Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2015;1218:277-92. doi: 10.1007/978-1-4939-1538-5_17.
Within the recent years, RNA interference (RNAi) has become an almost standard method for in vitro knockdown of any target gene of interest. Now, one major focus is to further explore its potential therapeutic use. From the mechanism, it becomes clear that small interfering RNAs (siRNAs) play a pivo
PMID 25319658

Prophylaxis and management of venous thromboembolism in patients with myeloproliferative neoplasms: consensus statement of the Haemostasis Working Party of the German Society of Hematology and Oncology (DGHO), the Austrian Society of Hematology and Oncology (ÖGHO) and Society of Thrombosis and Haemostasis Research (GTH e.V.).

Kreher S1, Ochsenreither S, Trappe RU, Pabinger I, Bergmann F, Petrides PE, Koschmieder S, Matzdorff A, Tiede A, Griesshammer M, Riess H.
Annals of hematology.Ann Hematol.2014 Dec;93(12):1953-63. doi: 10.1007/s00277-014-2224-8. Epub 2014 Oct 14.
Patients with Philadelphia chromosome-negative myeloproliferative neoplasms (MPN) like polycythemia vera and essential thrombocythemia are at increased risk of arterial and venous thrombosis. Strategies of prevention may consist of platelet aggregation inhibitors and/or cytoreductive agents dependin
PMID 25307456

Acute basophilic leukemia presenting with maculopapular rashes and a gastric ulcer: A case report.

Luo XH1, Zhu Y2, Tang XQ1.
Oncology letters.Oncol Lett.2014 Dec;8(6):2513-2516. Epub 2014 Sep 17.
Acute basophilic leukemia (ABL) is a rare and poorly characterized form of leukemia. The case of a 65-year-old male who complained of dizziness, maculopapular skin lesions and melena is described in the current report. A gastroscopy was conducted and indicated a gastric antral ulcer. The diagnosis o
PMID 25364419