O6-メチルグアニン-DNAメチル化酵素、O6-メチルグアニン-DNAメチルトランスフェラーゼ
WordNet
- the 15th letter of the Roman alphabet (同)o
- the blood group whose red cells carry neither the A nor B antigens; "people with type O blood are universal donors" (同)type_O, group O
- the 4th letter of the Roman alphabet (同)d
PrepTutorEJDIC
- 《呼び掛けの名前の前につけて》『おお』,あ / (驚き・恐れ・喜び・苦痛などを表して)『おお』,ああ,まあ / 《肯定・否定を強めて》
- oxygenの化学記号
- ohmオーム / Old
- deuteriumの化学記号
- deoxyribonucleic acidディオキシリボ核酸
- osmiumの化学記号
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- MGMT promoter methylation status as a prognostic factor for the outcome of gamma knife radiosurgery for recurrent glioblastoma.
- Kim BS1, Kong DS2, Seol HJ2, Nam DH2, Lee JI3.
- Journal of neuro-oncology.J Neurooncol.2017 May 23. doi: 10.1007/s11060-017-2478-9. [Epub ahead of print]
- PMID 28536992
- DNA-Targeted Inhibition of MGMT.
- Marsoner T1, Schmidt OP1, Triemer T1, Luedtke NW1.
- Chembiochem : a European journal of chemical biology.Chembiochem.2017 May 18;18(10):894-898. doi: 10.1002/cbic.201600652. Epub 2017 Apr 7.
- PMID 28177192
- Defining optimal cutoff value of MGMT promoter methylation by ROC analysis for clinical setting in glioblastoma patients.
- Yuan G1, Niu L2, Zhang Y2, Wang X1, Ma K3, Yin H2, Dai J2, Zhou W4, Pan Y5,6.
- Journal of neuro-oncology.J Neurooncol.2017 May 17. doi: 10.1007/s11060-017-2433-9. [Epub ahead of print]
- PMID 28516344
Japanese Journal
- グリオーマの遺伝子異常に基づいた化学療法の最新知見
- 夏目 敦至,Lushun Chalise,若林 俊彦
- 脳神経外科ジャーナル 24(6), 386-398, 2015
- … グリオーマ (神経膠腫) の化学療法を理解するために必要な遺伝子変化として, O6-methylguanine DNA-methyltransferase (MGMT), 染色体1p19q, epidermal growth factor receptor (EGFR), TP53, およびisocitrate dehyrodogenase (IDH) 1 & IDH 2等が特に着目されている. …
- NAID 130005083637
- グリコーゲンシンターゼキナーゼ-3βの阻害によるc-Mycを介したMGMT promoter メチル化促進に起因する膠芽腫細胞のテモゾロミド感受性増強効果
- Temozolomide (TMZ)を中心とした悪性神経膠腫化学療法の世界の現状
- 若林 俊彦
- Neuro-Oncologyの進歩 21(3), 45-50, 2014
- … However, its clinical outcomes depend on the O6-methylguanine-DNA methyltransferase (MGMT) status, and MGMT modification is one of the key factors to obtain greater clinical benefits in the future.TMZ and other antitumor drugs, especially anti VEGF antibody (Avascin®) and/or BCNU wafer (Gliadel®) combination therapy have been aggressively tried for the treatment of gliomas. …
- NAID 130005002163
Related Links
- 5ice: crystal structure of (s)-norcoclaurine 6-o-methyltransferase with s-adenosyl-l-homocysteine and norlaudanosoline ... 鎖名 残基 ligand A GLY109-ALA110 2H4: (1S)-1-(3,4-dihydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol A
- S-adenosyl-L-methionine:mRNA (2'-O-methyladenosine-6-N-)-methyltransferase activity S-adenosyl-L-methionine:mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity Statements subclass of mRNA methyltransferase ...
★リンクテーブル★
[★]
[★]
- 英
- deoxyribonucleic acid
- 同
- デオキシリボ核酸
- 関
- リボ核酸 RNA
[★]
メチルトランスフェラーゼ、メチル基転移酵素、メチル化酵素
[★]
- 同
- 食道入口部
[★]
メチルトランスフェラーゼ