- 関
- Na-H exchanger、Na+-H+ exchanger、sodium-hydrogen antiporter、sodium-hydrogen exchanger
WordNet
- the 8th letter of the Roman alphabet (同)h
- the 14th letter of the Roman alphabet (同)n
PrepTutorEJDIC
- hydrogenの化学記号
- 鉛筆の硬度 / 《俗》heroin
- nitrogenの化学記号
- sodium(ラテン語natrium)の化学記号
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/03/19 08:51:05」(JST)
[Wiki en表示]
The sodium–hydrogen antiporter or sodium–hydrogen exchanger is a membrane protein found in many cells, and especially in those of the nephron of the kidney. Specifically in the intercalary cells of the collecting duct. The membrane pump is primarily responsible for maintaining the balance of pH.[1]
Isoforms
There are several isoforms of the antiporter:
- Sodium–hydrogen antiporter 1
- Sodium–hydrogen antiporter 2
- Sodium–hydrogen antiporter 3
- Sodium–hydrogen antiporter 5
- Sodium–hydrogen antiporter 6
- Sodium–hydrogen antiporter 8
References
- ^ [1]
External links
- Sodium-Hydrogen Exchanger at the US National Library of Medicine Medical Subject Headings (MeSH)
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Membrane transport protein: ion pumps, ATPases / ATP synthase (TC 3A2-3A3)
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| F-, V-, and A-type ATPase (3.A.2) |
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H+ (F-type)
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- H+ transporting, mitochondrial: ATP5A1
- ATP5B
- ATP5C1
- ATP5C2
- ATP5D
- ATP5E
- ATP5F1
- ATP5G1
- ATP5G2
- ATP5G3
- ATP5H
- ATP5I
- ATP5J
- ATP5J2
- ATP5L
- ATP5L2
- ATP5O
- ATP5S
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H+ (V-type)
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- H+ transporting, lysosomal: ATP6AP1
- ATP6AP2
- ATP6V1A
- ATP6V1B1
- ATP6V1B2
- ATP6V1C1
- ATP6V1C2
- ATP6V1D
- ATP6V1E1
- ATP6V1E2
- ATP6V1F
- ATP6V1G1
- ATP6V1G2
- ATP6V1G3
- ATP6V1H
- ATP6V0A1
- ATP6V0A2
- ATP6V0A4
- ATP6V0B
- ATP6V0C
- ATP6V0D1
- ATP6V0D2
- ATP6V0E
- ATP6V0E1
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A-ATPase
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found in Archea
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| P-type ATPase (3.A.3) |
- 3.A.3.1.1: Na+/K+ transporting: ATP1A1
- ATP1A2
- ATP1A3
- ATP1A4
- ATP1B1
- ATP1B2
- ATP1B3
- ATP1B4
- ATP1G1
- 3.A.3.1.2: H+/K+
- H+/K+ exchanging: ATP4A
- ATP4B
- 3.A.3.1.4: H+/K+ transporting, nongastric: ATP12A
- 3.A.3.2: Ca+ (SERCA, PMCA, SPCA) / Ca++ transporting: ATP2A1
- ATP2A2
- ATP2A3
- ATP2B1
- ATP2B2
- ATP2B3
- ATP2B4
- ATP2C1
- 3.A.3.5: Cu++ transporting: ATP7A
- ATP7B
- 3.A.3.8.8: flippase: ATP8A2
- Mg++ transporting: ATP3
- Class I, type 8: ATP8A1
- ATP8B1
- ATP8B2
- ATP8B3
- ATP8B4
- Class II, type 9: ATP9A
- ATP9B
- Class V, type 10: ATP10A
- ATP10B
- ATP10D
- Class VI, type 11: ATP11A
- ATP11B
- ATP11C
- type 13: ATP13A1
- ATP13A2
- ATP13A3
- ATP13A4
- ATP13A5
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see also ATPase disorders
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| Description |
- Cell membranes
- Cell adhesion
- Membrane transport
- ion channels
- vesicular transport
- solute carrier
- ABC transporters
- ATPase
- oxidoreduction-driven
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| Disease |
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UpToDate Contents
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English Journal
- Toward a biophysical understanding of the salt stress response of individual plant cells.
- Foster KJ1, Miklavcic SJ2.
- Journal of theoretical biology.J Theor Biol.2015 Nov 21;385:130-42. doi: 10.1016/j.jtbi.2015.08.024. Epub 2015 Sep 8.
- We present and explore a kinetic model of ion transport across and between the membranes of an isolated plant cell with an emphasis on the cell's response to salt (Na(+)) stress. The vacuole, cytoplasm and apoplast are treated as concentric regions separated by tonoplast and plasma membranes. The mo
- PMID 26362103
- NhaA antiporter functions using 10 helices, and an additional 2 contribute to assembly/stability.
- Padan E1, Danieli T2, Keren Y2, Alkoby D3, Masrati G4, Haliloglu T5, Ben-Tal N4, Rimon A3.
- Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2015 Oct 13;112(41):E5575-82. doi: 10.1073/pnas.1510964112. Epub 2015 Sep 28.
- The Escherichia coli Na(+)/H(+) antiporter (Ec-NhaA) is the best-characterized of all pH-regulated Na(+)/H(+) exchangers that control cellular Na(+) and H(+) homeostasis. Ec-NhaA has 12 helices, 2 of which (VI and VII) are absent from other antiporters that share the Ec-NhaA structural fold. This α
- PMID 26417087
- A novel Na(+)(K(+))/H(+) antiporter plays an important role in the growth of Acetobacter tropicalis SKU1100 at high temperatures via regulation of cation and pH homeostasis.
- Soemphol W1, Tatsuno M2, Okada T2, Matsutani M2, Kataoka N2, Yakushi T2, Matsushita K3.
- Journal of biotechnology.J Biotechnol.2015 Oct 10;211:46-55. doi: 10.1016/j.jbiotec.2015.06.397. Epub 2015 Jun 19.
- A gene encoding a putative Na(+)/H(+) antiporter was previously proposed to be involved in the thermotolerance mechanism of Acetobacter tropicalis SKU 1100. The results of this study show that disruption of this antiporter gene impaired growth at high temperatures with an external pH>6.5. The gro
- PMID 26100236
Japanese Journal
- 微生物に学ぶアルカリ性環境適応戦略(セミナー「生物のストレス受容のメカニズム-分子レベルから細胞レベルまで-」)
- 伊藤 政博
- 低温生物工学会誌 57(1), 25-32, 2011-04-15
- … In alkaliphilic Bacillus, Na^+-dependent pH homeostasis involves the Na^+/H^+ antiport activities as well as Na^+ re-entry routes. … A predominant role was evident for the NaChBac (voltage-dependent) Na channel of alkaliphilic B. … pseudofirmus OF4 at sub-optimal [Na^+]. …
- NAID 110008671117
- Glultamate 85 Is Involved in the Sodium/Proton Exchange Activity of the Escherichia coli ChaA
- FUKAYA Fuminori,TANAKA Kimihiro,WADITEE Rungaroon,TANAKA Yoshito,NAKAMURA Tatsunosuke,TAKABE Teruhiro
- Bioscience, biotechnology, and biochemistry 74(5), 1116-1119, 2010-05-23
- … Hitherto, the roles of specific amino acid residues of ChaA, one of three Na+/H+ antiporters in Escherichia coli, in exchange activity have not been reported. …
- NAID 10027555683
Related Links
- A gene encoding an Na+/H+ antiporter was cloned from chromosomal DNA of Vibrio parahaemolyticus, a slightly halophilic bacterium, and expressed in Escherichia c ... 3.2. Na + /H + antiport activity in membrane vesicles ...
- RESULTS We initially examined whether the Na + /H + exchanger could play a role in the differentiation of P19 cells. Cells were treated with retinoic acid in the presence of Hoe 694, a potent inhibitor of the Na + /H + exchanger.
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ナトリウム・プロトンアンチポーター、Na+/H+アンチポーター、Na+/H+交換輸送体
- 関
- Na-H antiporter、Na-H exchanger、Na+-H+ exchanger、sodium-hydrogen exchanger
- 同
- Na+-H+
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- 英
- Na+-H+ exchanger、Na-H exchanger、Na-H antiporter、sodium-hydrogen exchanger、sodium-hydrogen antiporter
- 関
- ナトリウム・プロトンアンチ・ーター、Na+/H+アンチ・ーター
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- 関
- Na-H antiporter、Na+-H+ exchanger、sodium-hydrogen antiporter、sodium-hydrogen exchanger
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- 関
- Na-H antiporter、Na-H exchanger、sodium-hydrogen antiporter、sodium-hydrogen exchanger
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- 関
- Na-H antiporter、Na-H exchanger、Na+-H+ exchanger、sodium-hydrogen antiporter
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