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1. 気管支肺分画症 bronchopulmonary sequestration
2. 特発性肺線維症の病因 pathogenesis of idiopathic pulmonary fibrosis
3. 気管支肺分画症の出生前診断およびマネージメント prenatal diagnosis and management of bronchopulmonary sequestration
4. 微細欠失症候群（12番～22番染色体） microdeletion syndromes chromosomes 12 to 22
5. 先天性の細胞遺伝学的異常 congenital cytogenetic abnormalities

High throughput sequencing of cyclic peptide immobilized on a gel-type single bead.

Nokihara K1, Kasama T2, Tominaga Y3, Kitagawa A3, Hirata A3, Ohyama T3, Yazawa I4.
Amino acids.Amino Acids.2016 Nov;48(11):2491-2499. Epub 2016 Jun 8.
Relatively larger scale peptide libraries immobilized on a gel-type solid support consisting of 24 natural and non-natural amino acids by the "split and combine method" have been constructed to find interacting molecules. The diversity was ca. 200 millions of hexapeptides with cysteinyl residues for
PMID 27277187

Distinguishing between Leucine and Isoleucine by Integrated LC-MS Analysis Using an Orbitrap Fusion Mass Spectrometer.

Xiao Y1, Vecchi MM1, Wen D1.
Analytical chemistry.Anal Chem.2016 Nov 1;88(21):10757-10766. Epub 2016 Oct 14.
Despite the great success of mass spectrometry (MS) for de novo protein sequencing, Leu and Ile have been generally considered to be indistinguishable by MS because their molecular masses are exactly the same. Positioning of incorrect Leu/Ile residues in variable domains, especially in CDRs (complem
PMID 27704771

Structural and thermodynamic characterisation of L94F mutant of horse cytochrome c.

Khan SH1, Kumar A2, Prakash A1, Taneja B2, Islam A1, Hassan MI1, Ahmad F3.
International journal of biological macromolecules.Int J Biol Macromol.2016 Nov;92:202-212. doi: 10.1016/j.ijbiomac.2016.06.096. Epub 2016 Jul 1.
Mammalian mitochondrial cytochromes c (cyts c) has a conserved Leu94 which is replaced by valine/isoleucine in some lower eukaryotes and prokaryotes. It is expected that nature substituted Leu94 with Val/Ile, for they have similar van der Waals volume and hydrophobicity with a difference in side cha
PMID 27377462