WordNet

any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
(biology) any agency bringing about activation; a molecule that increases the activity of an enzyme or a protein that increases the production of a gene product in DNA transcription
the 7th letter of the Roman alphabet (同)g

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1. 非小細胞肺癌における分子マーカー molecular markers in non small cell lung cancer
2. 幼児の食物蛋白誘発性直腸炎/大腸炎、腸疾患、および腸炎 food protein induced proctitis colitis enteropathy and enterocolitis of infancy
3. 活性化プロテインＣ抵抗性および第V因子ライデン activated protein c resistance and factor v leiden
4. 肥大型心筋症の遺伝学 genetics of hypertrophic cardiomyopathy
5. 血管内皮機能および血栓溶解療法の基本的メカニズム vascular endothelial function and fundamental mechanisms of fibrinolysis thrombolysis

Higashi K, Kubo H, Watanabe H, Fujimori K, Mikami T, Kaneko H.SourceEnvironmental Health Science Laboratory, Sumitomo Chemical Co., Ltd, Osaka, Japan. higashik2@sc.sumitomo-chem.co.jp
FEBS letters.FEBS Lett.2011 Aug 19;585(16):2587-91. Epub 2011 Jul 23.
Recently, we identified ganglioside GM2 activator protein (GM2AP) as a novel adipokine, and revealed that treatment of cultured cells with GM2AP impairs insulin signal transduction. The aim of this study was to examine the impact of GM2AP on glucose metabolism in vivo. Injection of recombinant GM2AP
PMID 21784073

Porter BF, Lewis BC, Edwards JF, Alroy J, Zeng BJ, Torres PA, Bretzlaff KN, Kolodny EH.SourceDepartment of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843-4467, USA. bporter@cvm.tamu.edu
Veterinary pathology.Vet Pathol.2011 Jul;48(4):807-13. Epub 2010 Dec 1.
The G(M2) gangliosidoses are a group of lysosomal storage diseases caused by defects in the genes coding for the enzyme hexosaminidase or the G(M2) activator protein. Four Jacob sheep from the same farm were examined over a 3-year period for a progressive neurologic disease. Two lambs were 6-month-o
PMID 21123862

The Possible Contribution of a General Glycosphingolipid Transporter, GM2 Activator Protein, to Atherosclerosis

Inefficiency in GM2 Ganglioside Elimination by Human Lysosomal β-Hexosaminidase β-Subunit Gene Transfer to Fibroblastic Cell Line Derived from Sandhoff Disease Model Mice(Biochemistry)

ITAKURA Tomohiro,KUROKI Aya,ISHIBASHI Yasuhiro,TSUJI Daisuke,KAWASHITA Eri,HIGASHINE Yukari,SAKURABA Hitoshi,YAMANAKA Shoji,ITOH Kohji
Biological & pharmaceutical bulletin 29(8), 1564-1569, 2006-08-01
… Sandhoff disease (SD) is an autosomal recessive GM2 gangliosidosis caused by the defect of lysosomal β-hexosaminidase (Hex) β-subunit gene associated with neurosomatic manifestations. … We demonstrate here that elimination of GM2 ganglioside (GM2) accumulated in the fibroblastic cell line derived from SD mice (FSD) did not occur when the HEXB gene only was transfected. …
NAID 110005663990