WordNet

the 4th letter of the Roman alphabet (同)d
(biochemistry) purine base found in DNA and RNA; pairs with thymine in DNA and with uracil in RNA (同)A

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1. 母体血中の無細胞胎児核酸を使った出生前診断 prenatal diagnosis using cell free fetal nucleic acids in maternal blood
2. 分子遺伝学の原理 principles of molecular genetics
3. 遺伝性疾患の基本原則 basic principles of genetic disease
4. 淋菌感染症の診断 diagnosis of gonococcal infections
5. ポリメラーゼ連鎖反応(PCR) polymerase chain reaction

Transient overexpression of DNA adenine methylase enables efficient and mobile genome engineering with reduced off-target effects.

Lennen RM1, Nilsson Wallin AI1, Pedersen M1, Bonde M1, Luo H1, Herrgård MJ1, Sommer MO2.
Nucleic acids research.Nucleic Acids Res.2015 Oct 22. pii: gkv1090. [Epub ahead of print]
Homologous recombination of single-stranded oligonucleotides is a highly efficient process for introducing precise mutations into the genome of E. coli and other organisms when mismatch repair (MMR) is disabled. This can result in the rapid accumulation of off-target mutations that can mask desired
PMID 26496947

Investigation of the C-terminal domain of the bacterial DNA-(adenine N6)-methyltransferase CcrM.

Maier JA1, Albu RF1, Jurkowski TP1, Jeltsch A2.
Biochimie.Biochimie.2015 Oct 15. pii: S0300-9084(15)00329-6. doi: 10.1016/j.biochi.2015.10.011. [Epub ahead of print]
CcrM-related DNA-(adenine N6)-methyltransferases play very important roles in the biology of Caulobacter crescentus and other alpha-proteobacteria. These enzymes methylate GANTC sequences, but the molecular mechanism by which they recognize their target sequence is unknown. We carried out multiple s
PMID 26475175

DNA adenine methylation modulates pathogenicity of Klebsiella pneumoniae genotype K1.

Fang CT1, Yi WC2, Shun CT3, Tsai SF4.
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi.J Microbiol Immunol Infect.2015 Sep 9. pii: S1684-1182(15)00845-2. doi: 10.1016/j.jmii.2015.08.022. [Epub ahead of print]
BACKGROUND/PURPOSE: Klebsiella pneumoniae genotype K1 is a highly virulent pathogen that causes liver abscess and metastatic endophthalmitis/meningitis. Whether its pathogenicity is controlled by DNA adenine methylase (Dam), an epigenetic regulator of bacterial virulence gene expression, is yet unkn
PMID 26427879

Cassette DNA Fragment for Selection and Sexing of Preimplantation Bovine Transgenic Embryos

Kodaira Koko,Itoh Kazumi,Hirabayashi Masumi [他],KODAIRA Kunihiko,UEDA Masatsugu
The Journal of reproduction and development 45(1), 105-110, 1999-02-01
… A 369-bp cassette DNA fragment (LACFE) was constructed for simultaneous detection of exogenous gene integration and sexing of preimplantation bovine embryos. … Bovine pronucleus embryos were microinjected with the LACFE modified by DNA adenine methylase. …
NAID 130000055153