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English Journal

Yokoyama Y1, Aoyagi S1, Shimanouchi T2, Iwamura M2, Iwai H3.
Biointerphases.Biointerphases.2016 Jun 28;11(2):02A314. doi: 10.1116/1.4940706.
Amyloid beta (Aβ) peptides are considered to be strongly related to Alzheimer's disease. Aβ peptides form a β-sheet structure on hard lipid membranes and it would aggregate to form amyloid fibrils, which are toxic to cells. However, the aggregation mechanism of Aβ is not fully understood. To eva
PMID 26822505

Free energy landscapes of sodium ions bound to DMPC-cholesterol membrane surfaces at infinite dilution.

Yang J1, Bonomi M, Calero C, Martí J.
Physical chemistry chemical physics : PCCP.Phys Chem Chem Phys.2016 Apr 7;18(13):9036-41. doi: 10.1039/c5cp05527j. Epub 2016 Mar 11.
Exploring the free energy landscapes of metal cations on phospholipid membrane surfaces is important for the understanding of chemical and biological processes in cellular environments. Using metadynamics simulations we have performed systematic free energy calculations of sodium cations bound to DM
PMID 26967312

Neutron reflection study of the interaction of the eukaryotic pore-forming actinoporin equinatoxin II with lipid membranes reveals intermediate states in pore formation.

Wacklin HP1, Bremec BB2, Moulin M3, Rojko N4, Haertlein M3, Forsyth T3, Anderluh G5, Norton RS6.
Biochimica et biophysica acta.Biochim Biophys Acta.2016 Apr;1858(4):640-52. doi: 10.1016/j.bbamem.2015.12.019. Epub 2015 Dec 17.
Equinatoxin II (EqtII), a eukaryotic pore-forming toxin, lyses cell membranes through a mechanism involving the insertion of its N-terminal α-helix into the membrane. EqtII pore formation is dependent on sphingomyelin (SM), although cholesterol (Chol) and membrane microdomains have also been sugges
PMID 26706098

Anti-tumor Effects of Cationic Hybrid Liposomes against Colon Carcinoma along with Apoptosis in Vitro

Hino Motoki,Ichihara Hideaki,Matsumoto Yoko,Ueoka Ryuichi
Biological and Pharmaceutical Bulletin 35(11), 2097-2101, 2012
… New-type three-component cationic hybrid liposomes (HLs) composed of dimyristoylphosphatidylcholine (DMPC), polyoxyethylene(21)dodecyl ether (C12(EO)21) and O,O′-ditetradecanoyl-N-(α-trimethylammonioacetyl) diethanolamine chloride (2C14ECl) were produced. … Cationic HLs were smaller and more stable than pure DMPC liposomes. …
NAID 130001872276

Jaromin Anna,Korycińska Mariola,Piętka-Ottlik Magdalena,Musiał Witold,Peczyńska-Czoch Wanda,Kaczmarek Łukasz,Kozubek Arkadiusz
Biological and Pharmaceutical Bulletin 35(9), 1432-1439, 2012
… Moreover, a correlation between binding to neutral dimyristoylphosphatidylcholine (DMPC) or negative charged dimyristoylphosphatidylcholine : dimyristoylphosphatidylglycerol (DMPC : DMPG, 9 : 1 w/w) liposomes, as well as to erythrocyte ghosts and pKa, was also found. …
NAID 130001872063

1A1512 新規合成部分フッ素化フォスファチジルコリンF4-DMPC二重層膜の水和について(生体膜・人工膜1(構造・物性、ダイナミクス),第49回日本生物物理学会年会)

Takahashi Hiroshi,Yoshino Masaru,Takagi Toshiyuki,Baba Teruhiko,Kanamori Toshiyuki,Sonoyama Masashi
生物物理 51(SUPPLEMENT_1), S28, 2011-08-15
NAID 110008902972