English Journal

siRNA carriers based on carbosilane dendrimers affect zeta potential and size of phospholipid vesicles.

Ionov M, Garaiova Z, Waczulikova I, Wróbel D, Pędziwiatr-Werbicka E, Gomez-Ramirez R, de la Mata FJ, Klajnert B, Hianik T, Bryszewska M.SourceDepartment of General Biophysics, University of Lodz, Pomorska 141/143 St., 90-236, Lodz, Poland.
Biochimica et biophysica acta.Biochim Biophys Acta.2012 Sep;1818(9):2209-16. Epub 2012 May 2.
One of the major limitations in gene therapy is an inability of naked siRNA to passively diffuse through negatively charged cell membranes. Therefore, the siRNA transport into a cell requires efficient carriers. In this work we analyzed the charge-dependent interaction of the complexes of cationic c
PMID 22575422

Human erythrocytes and neuroblastoma cells are in vitro affected by sodium orthovanadate.

Suwalsky M, Fierro P, Villena F, Aguilar LF, Sotomayor CP, Jemiola-Rzeminska M, Strzalka K, Gul-Hinc S, Ronowska A, Szutowicz A.SourceFaculty of Chemical Sciences, University of Concepción, PO Box 160-C, Concepción, Chile.
Biochimica et biophysica acta.Biochim Biophys Acta.2012 Sep;1818(9):2260-70. Epub 2012 Apr 21.
Research on biological influence of vanadium has gained major importance because it exerts potent toxic, mutagenic, and genotoxic effects on a wide variety of biological systems. However, hematological toxicity is one of the less studied effects. The lack of information on this issue prompted us to
PMID 22546530

Japanese Journal

上岡秀嗣,古水雄志,後藤浩一,上岡龍一
化学工学論文集 = Kagaku kogaku ronbunshu 37(3), 271-276, 2011-07-20
温州みかんの果実と果汁より溶媒抽出した成分を90 mol% DMPC/10 mol% Tween 80ハイブリッドリポソームに含有し，ヒト肝臓がん（HuH-7）細胞およびヒト胃がん（MKN-45）細胞に対する増殖抑制効果をin vitroで検討した．高極性溶媒抽出物では，果実および果汁ともに，抑制効果はほとんどみられず，MKN-45細胞に対して約20%の増殖抑制効果を示した．一方，低極性溶媒抽出物 …
NAID 10029241754

市原英明,巽一喜,後藤浩一,松本陽子,上岡龍一
化学工学論文集 37(1), 192-196, 2011-03-20
イタドリ根茎より溶媒抽出した成分を90 mol% DMPC/10 mol% Tween 20ハイブリッドリポソーム（HL）に含有し，ヒトT細胞白血病（MOLT-4）細胞に対する増殖抑制効果をin vitroで検討した．石油エーテル抽出物（1）とクロロホルム抽出物（3）を含むHLのMOLT-4細胞に対する増殖抑制性効果が得られた．特に，抽出物（3）を含むHLは，他の抽出物含有HLに比べ，著しい増殖抑 …
NAID 10027970840

Electrostatic effects influence the formation of two-dimensional crystals of bacteriorhodopsin reconstituted into dimyristoylphosphatidylcholine membranes