AT1 receptor antagonists

AT1受容体拮抗薬

WordNet

1. the 1st letter of the Roman alphabet (同)a
2. the blood group whose red cells carry the A antigen (同)type_A, group A
3. a drug that neutralizes or counteracts the effects of another drug
4. a muscle that relaxes while another contracts; "when bending the elbow the triceps are the antagonist"
5. a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response

PrepTutorEJDIC

1. answer / ampere
2. 対立する人,敵対者,競争相手(opponent)
3. =sense organ / 受信装置

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• 1. アンギオテンシン変換酵素阻害剤とアンギオテンシン受容体拮抗剤との相違 differences between angiotensin converting enzyme inhibitors and receptor blockers
• 2. Prevention and treatment of chemotherapy-induced nausea and vomiting in adults
• 3. 制吐剤の特性 characteristics of antiemetic drugs
• 4. 駆出率低下を伴う心不全におけるエンドセリンの役割 role of endothelin in heart failure with reduced ejection fraction
• 5. 心不全におけるアンギオテンシン変換酵素阻害剤およびアンギオテンシン受容体拮抗剤：作用機序 angiotensin converting enzyme inhibitors and receptor blockers in heart failure mechanisms of action

English Journal

• Differential regulation of angiotensin converting enzyme 2 and nuclear factor-κB by angiotensin II receptor subtypes in type 2 diabetic kidney.

• Pandey A1, Goru SK1, Kadakol A1, Malek V1, Gaikwad AB2.
• Biochimie.Biochimie.2015 Aug 10. pii: S0300-9084(15)00252-7. doi: 10.1016/j.biochi.2015.08.005. [Epub ahead of print]
• Angiotensin II (Ang II) acts through Angiotensin Converting Enzyme (ACE)/Ang II type 1 receptor (AT1R) axis to promote renal failure whereas the Ang II type 2 receptor (AT2R)/Angiotensin Converting Enzyme 2 (ACE2)/Ang1-7/Mas axis constitutes the protective arm of Renin Angiotensin System (RAS). Thou
• PMID 26271886

• Angiotensin type 1a receptors on corticotropin-releasing factor neurons contribute to the expression of conditioned fear1.

• Hurt RC1,2, Garrett JC1,2, Keifer OP Jr1,2, Linares A3,4, Couling L4, Speth RC4,5, Ressler KJ1,2,6, Marvar PJ7.
• Genes, brain, and behavior.Genes Brain Behav.2015 Aug 10. doi: 10.1111/gbb.12235. [Epub ahead of print]
• Although generally associated with cardiovascular regulation, angiotensin II receptor type 1a (AT1a R) blockade in mouse models and humans has also been associated with enhanced fear extinction and decreased post-traumatic stress disorder (PTSD) symptom severity, respectively. The mechanisms mediati
• PMID 26257395

• Lack of weight gain after angiotensin AT1 receptor blockade in diet-induced obesity is partly mediated by an angiotensin-(1-7)/Mas-dependent pathway.

• Schuchard J1,2, Winkler M1, Stölting I1, Schuster F1, Vogt FM3, Barkhausen J3, Thorns C4, Santos RA5, Bader M5,6,7,8,9, Raasch W1,2.
• British journal of pharmacology.Br J Pharmacol.2015 Aug;172(15):3764-78. doi: 10.1111/bph.13172. Epub 2015 Jun 12.
• BACKGROUND AND PURPOSE: Angiotensin AT1 receptor antagonists induce weight loss; however, the mechanism underlying this phenomenon is unknown. The Mas receptor agonist angiotensin-(1-7) is a metabolite of angiotensin I and of angiotensin II . As an agonist of Mas receptors, angiotensin-(1-7) has ben
• PMID 25906670

Japanese Journal

• Inverse agonism: the classic concept of GPCRs revisited

• Endocrine Journal advpub(0), 2016
• NAID 130005131264

• 本態性高血圧患者のアンジオテンシン受容体遮断薬に対するべニジピンの追加投与が、スケーリング係数に及ぼす影響について

• 東京女子医科大学雑誌 83(2), 95-105, 2013-04-25
• NAID 110009581136

• Effects of Angiotensin Type I Receptor Blockade on the Cardiac Raf/MEK/ERK Cascade Activated via Adrenergic Receptors

• Journal of pharmacological sciences 113(3), 224-233, 2010-07-20
• NAID 10029889243

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★リンクテーブル★

リンク元	「AT1受容体拮抗薬」
関連記事	「AT」「A」

「AT1受容体拮抗薬」

　　[★]

英

AT1 receptor antagonists

関

AT1受容体

「AT」

　　[★]

• 無酸素性作業閾値 anaerobic threshold
• 毛細血管拡張性運動失調症 ataxia telangiectasia
• アンチトロンビン antithrombin
• 加速時間 acceleration time

「A」

　　[★]

• アデニン adenine
• アデノシン adenosine
• アラニン alanine