- 関
- adenosine diphosphate ribose、adenosine diphosphoribose、ADPR
WordNet
- the 1st letter of the Roman alphabet (同)a
- the blood group whose red cells carry the A antigen (同)type_A, group A
- a pentose sugar important as a component of ribonucleic acid
- in the Christian era; used before dates after the supposed year Christ was born; "in AD 200" (同)A.D., anno_Domini
PrepTutorEJDIC
- answer / ampere
- リボース(リボ核酸の加水分解によって得られる五炭糖)
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/12/10 09:50:42」(JST)
[Wiki en表示]
Adenosine diphosphate ribose
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Names |
Other names
ADP ribose
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Identifiers |
CAS Number
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20762-30-5 N |
ChEMBL |
ChEMBL1161865 N |
ChemSpider |
388340 N |
InChI
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InChI=1S/C15H23N5O14P2/c16-12-7-13(18-3-17-12)20(4-19-7)14-10(24)9(23)6(31-14)2-30-35(26,27)34-36(28,29)33-15-11(25)8(22)5(1-21)32-15/h3-6,8-11,14-15,21-25H,1-2H2,(H4,16,17,18,26,27,28,29)/p+1/t5-,6+,8-,9+,10+,11-,14+,15+/m0/s1 N
Key: YNCNQNWXUFCWJS-DKMYFHGXSA-O N
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InChI=1/C15H23N5O14P2/c16-12-7-13(18-3-17-12)20(4-19-7)14-10(24)9(23)6(31-14)2-30-35(26,27)34-36(28,29)33-15-11(25)8(22)5(1-21)32-15/h3-6,8-11,14-15,21-25H,1-2H2,(H4,16,17,18,26,27,28,29)/p+1/t5-,6+,8-,9+,10+,11-,14+,15+/m0/s1
Key: YNCNQNWXUFCWJS-LKOYDKQFBH
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Jmol interactive 3D |
Image |
MeSH |
Adenosine+Diphosphate+Ribose |
PubChem |
439200 |
SMILES
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O=P(O[C@H]1O[C@H]([C@H](O)[C@@H]1O)CO)(O)OP(=O)(OC[C@H]4O[C@@H]([n+]3c2ncnc(N)c2nc3)[C@H](O)[C@@H]4O)O
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Properties |
Chemical formula
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C15H23N5O14P2 |
Molar mass |
559.316 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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N verify (what is YN ?) |
Infobox references |
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Adenosine diphosphate ribose is an ester molecule formed into chains by the enzyme poly ADP ribose polymerase. It binds to and activates the TRPM2 ion channel.[1]
See also
- Adenosine diphosphate
- Ribose
References
- ^ Fonfria E, Marshall IC, Benham CD; et al. (September 2004). "TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase". Br. J. Pharmacol. 143 (1): 186–92. doi:10.1038/sj.bjp.0705914. PMC 1575275. PMID 15302683.
UpToDate Contents
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English Journal
- NGF promotes long-term memory formation by activating poly(ADP-ribose)polymerase-1.
- Wang SH, Liao XM, Liu D, Hu J, Yin YY, Wang JZ, Zhu LQ.SourceDepartment of Pathophysiology, Key Laboratory of Neurological Disease of Education Ministry of China, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, China; College of Life Sciences, Central China Normal University, HuBei Province Key Laboratory of Genetic Regulation and Integrative Biology, Wuhan 430079, China.
- Neuropharmacology.Neuropharmacology.2012 Nov;63(6):1085-92. Epub 2012 Jul 4.
- Nerve growth factor (NGF) is a critical secreted protein that plays an important role in development, survival, and function of the mammalian nervous system. Previously reports suggest that endogenous NGF is essential for the hippocampal plasticity/memory and NGF deprivation induces the impairment o
- PMID 22771769
- Activation of lytic cycle of Epstein-Barr virus by suberoylanilide hydroxamic acid leads to apoptosis and tumor growth suppression of nasopharyngeal carcinoma.
- Hui KF, Ho DN, Tsang CM, Middeldorp JM, Tsao GS, Chiang AK.SourceDepartment of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong, China.
- International journal of cancer. Journal international du cancer.Int J Cancer.2012 Oct 15;131(8):1930-40. doi: 10.1002/ijc.27439. Epub 2012 Mar 8.
- Nasopharyngeal carcinoma (NPC) is strongly associated with Epstein-Barr virus (EBV). We reported that suberoylanilide hydroxamic acid (SAHA) induced EBV lytic cycle in EBV-positive gastric carcinoma cells and mediated enhanced cell death. However, expression of EBV lytic proteins was thought to exer
- PMID 22261816
Japanese Journal
- The caspase 3-dependent apoptotic effect of pycnogenol in human oral squamous cell carcinoma HSC-3 cells
- PARP Inhibitor PJ34 Suppresses Osteogenic Differentiation in Mouse Mesenchymal Stem Cells by Modulating BMP-2 Signaling Pathway
- International Journal of Molecular Sciences 16(10), 24820-24838, 2015-10-19
- NAID 120005676326
- Poly(ADP-ribose) polymerase 1 activation links ischemic acute kidney injury to interstitial fibrosis
Related Links
- ^Isabelle M, Moreel X, Gagné JP, Rouleau M, Ethier C, Gagné P, Hendzel MJ, Poirier GG (2010). "Investigation of PARP-1, PARP-2, and PARG interactomes by affinity-purification mass spectrometry". Proteome Sci 8: 22. doi:10 ...
- poly(ADP-Ribose)(pADPr)は,poly(ADP-Ribose)polymerase(PARP)によって合成され,NAD+を基質としてヒストンなどの核タンパク質に付加されるポリマーで,クロマチン構造の制御やDNA修復に関与することが報告されて ...
Related Pictures
★リンクテーブル★
[★]
- 英
- adenosine diphosphate ribose、ADP-ribose、ADPR
- 関
- ADP-リボース、アデノシン二リン酸リボース
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- 関
- adenosine diphosphoribose、ADP-ribose、ADPR
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- 関
- adenosine diphosphate ribose、ADP-ribose
[★]
- 関
- adenosine diphosphate ribose、ADP-ribose
[★]
- 英
- (n
- 関
- ADPリボース
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- 関
- ADP-ribosyltransferase、ADPRT
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- 関
- cADPR、cyclic ADPR
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リボース
- 関
- D-ribose