- 関
- 5-HT agonist、5-HT1 agonist、5-HT3 agonist、serotonergic agonist、serotonin agonist、serotonin receptor agonist
WordNet
- (biochemistry) a drug that can combine with a receptor on a cell to produce a physiological reaction
- a muscle that contracts while another relaxes; "when bending the elbow the biceps are the agonist"
- someone involved in a contest or battle (as in an agon)
- the 8th letter of the Roman alphabet (同)h
PrepTutorEJDIC
- hydrogenの化学記号
- 鉛筆の硬度 / 《俗》heroin
UpToDate Contents
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English Journal
- 5-HT1D receptor inhibits renal sympathetic neurotransmission by nitric oxide pathway in anesthetized rats.
- García-Pedraza JÁ1, García M1, Martín ML1, Morán A2.
- Vascular pharmacology.Vascul Pharmacol.2015 Sep;72:172-80. doi: 10.1016/j.vph.2015.05.003. Epub 2015 May 21.
- Although serotonin has been shown to inhibit peripheral sympathetic outflow, serotonin regulation on renal sympathetic outflow has not yet been elucidated. This study investigated which 5-HT receptor subtypes are involved. Wistar rats were anesthetized (sodium pentobarbital; 60mg/kg, i.p.), and prep
- PMID 26003124
- An Orally Active Phenylaminotetralin-Chemotype Serotonin 5-HT7 and 5-HT1A Receptor Partial Agonist That Corrects Motor Stereotypy in Mouse Models.
- Canal CE, Felsing DE, Liu Y, Zhu W, Wood JT, Perry CK, Vemula R, Booth RG.
- ACS chemical neuroscience.ACS Chem Neurosci.2015 Jul 15;6(7):1259-70. doi: 10.1021/acschemneuro.5b00099. Epub 2015 Jun 8.
- Stereotypy (e.g., repetitive hand waving) is a key phenotype of autism spectrum disorder, Fragile X and Rett syndromes, and other neuropsychiatric disorders, and its severity correlates with cognitive and attention deficits. There are no effective treatments, however, for stereotypy. Perturbation of
- PMID 26011730
- N-Benzyl-5-methoxytryptamines as Potent Serotonin 5-HT2 Receptor Family Agonists and Comparison with a Series of Phenethylamine Analogues.
- Nichols DE1, Sassano MF1, Halberstadt AL, Klein LM, Brandt SD2, Elliott SP3, Fiedler WJ4.
- ACS chemical neuroscience.ACS Chem Neurosci.2015 Jul 15;6(7):1165-75. doi: 10.1021/cn500292d. Epub 2015 Jan 21.
- A series of N-benzylated-5-methoxytryptamine analogues was prepared and investigated, with special emphasis on substituents in the meta position of the benzyl group. A parallel series of several N-benzylated analogues of 2,5-dimethoxy-4-iodophenethylamine (2C-I) also was included for comparison of t
- PMID 25547199
Japanese Journal
- Serotonergic Modulation of Absence-Like Seizures in Groggy Rats: a Novel Rat Model of Absence Epilepsy
- Ohno Yukihiro,Sofue Nobumasa,Imaoku Takuji,Morishita Eri,Kumafuji Kenta,Sasa Masashi,Serikawa Tadao
- Journal of Pharmacological Sciences advpub(0), 1008200444, 2010
- … To explore the role of the serotonergic system in modulating absence seizures, we examined the effects of 5-HT1A and 5-HT2 agonists on the incidence of spike-and-wave discharges (SWD) in Groogy (GRY) rats, a novel rat model of absence-like epilepsy. …
- NAID 130000302186
- セロトニン1A受容体アゴニストのSAMマウスへの影響
- NIIMI Kimie,TAKAHASHI Eiki,ITAKURA Chitoshi
- Experimental Animals 59(4), 441-447, 2010
- … The hallucinogenic chemical 1-[2,5-dimethoxy-4-iodophenyl]-2-aminopropane (DOI), a serotonin receptor 2A (5-HT2AR) agonist, evokes extracellular signal-regulated kinase 1/2 (ERK1/2) signaling and head-twitch behavior. …
- NAID 130000298604
Related Links
- Methysergide, a congener of methylergonovine, used in treatment of migraine blocks 5-HT2A and 5-HT2C receptors, but sometimes acts as partial agonist, in some preparations. The atypical antipsychotic ...
- Conversely, many SSRIs (but not fluoxetine, which is a 5-HT2C antagonist) indirectly stimulate 5-HT2C activity by increasing levels ... Inverse agonists may be required to fully extinguish 5-HT2C constitutive activity, and may prove useful in the ...
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- 関
- 5-HT1 agonist、5-HT2 agonist、5-HT3 agonist、serotonergic agent、serotonergic agonist、serotonin agonist、serotonin receptor agonist
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- 英
- 5-HT2 agonist
- 関
- セロトニン作動薬、5-HT1作動薬、セロトニン受容体作動薬、5-HT2アゴニスト、5-HT3アゴニスト、セロトニン刺激薬、セロトニン受容体刺激薬、5-HT3刺激薬、5-HT2刺激薬、5-HT2受容体刺激薬
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- 英
- 5-HT2 agonist
- 関
- セロトニン作動薬、5-HT1作動薬、セロトニン受容体作動薬、5-HT2作動薬、5-HT2アゴニスト、5-HT3アゴニスト、セロトニン刺激薬、セロトニン受容体刺激薬、5-HT3刺激薬、5-HT2受容体刺激薬
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- 関
- 5-HT agonist、5-HT1 agonist、5-HT2 agonist、5-HT3 agonist、serotonergic agent、serotonergic agonist、serotonin receptor agonist
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- 関
- 5-HT agonist、5-HT1 agonist、5-HT2 agonist、5-HT3 agonist、serotonergic agent、serotonin agonist、serotonin receptor agonist
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