platelet-derived growth factor

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/01/30 10:00:49」(JST)

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  • Amplified amperometric aptasensor for selective detection of protein using catalase-functional DNA-PtNPs dendrimer as a synergetic signal amplification label.
  • Zhang J1, Yuan Y1, biXie S1, Chai Y2, Yuan R3.
  • Biosensors & bioelectronics.Biosens Bioelectron.2014 Oct 15;60:224-30. doi: 10.1016/j.bios.2014.04.024. Epub 2014 Apr 26.
  • In this work, we present a new strategy to construct an electrochemical aptasensor for sensitive detection of platelet-derived growth factor BB (PDGF-BB) based on the synergetic amplification of a three-dimensional (3D) nanoscale catalase (CAT) enzyme-functional DNA-platinum nanoparticles (PtNPs) de
  • PMID 24813911
  • Death-associated protein kinase 3 mediates vascular structural remodelling via stimulating smooth muscle cell proliferation and migration.
  • Usui T, Sakatsume T, Nijima R, Otani K, Kazama K, Morita T, Kameshima S, Okada M, Yamawaki H.
  • Clinical science (London, England : 1979).Clin Sci (Lond).2014 Oct 1;127(8):539-48. doi: 10.1042/CS20130591.
  • Death-associated protein kinase 3 (DAPK3) also known as zipper-interacting kinase is a serine/threonine kinase that mainly regulates cell death and smooth muscle contraction. We have previously found that protein expression of DAPK3 increases in the mesenteric artery from spontaneously hypertensive
  • PMID 24814693
  • α-Synuclein impairs oligodendrocyte progenitor maturation in multiple system atrophy.
  • May VE1, Ettle B1, Poehler AM1, Nuber S2, Ubhi K2, Rockenstein E2, Winner B3, Wegner M4, Masliah E2, Winkler J5.
  • Neurobiology of aging.Neurobiol Aging.2014 Oct;35(10):2357-68. doi: 10.1016/j.neurobiolaging.2014.02.028. Epub 2014 Mar 4.
  • Multiple system atrophy (MSA), an atypical parkinsonian disorder, is characterized by α-synuclein (α-syn(+)) cytoplasmatic inclusions in mature oligodendrocytes. Oligodendrocyte progenitor cells (OPCs) represent a distinct cell population with the potential to replace dysfunctional oligodendrocyte
  • PMID 24698767


  • PDGFRβ expression in tumor stroma of pancreatic adenocarcinoma as a reliable prognostic marker
  • Yuzawa Sayaka,Kano Mitsunobu R.,Einama Takahiro,Nishihara Hiroshi
  • Medical Oncology 29(4), 2824-2830, 2012-12
  • … In general, desmoplasia is thought to promote tumor growth. … These include alpha smooth muscle actin (SMA) and platelet-derived growth factor (PDGF) receptor β (PDGFRβ). …
  • NAID 120004979507
  • 膵β細胞増殖におけるPDGFの役割
  • 福中 彩子,藤谷 与士夫,綿田 裕孝
  • 内分泌・糖尿病・代謝内科 35(3), 238-241, 2012-09
  • NAID 40019457079


platelet-derived growth factor n. A substance in platelets that is mitogenic for cells at the site of a wound, causing endothelial proliferation. factor [fak´ter] an agent or element that contributes to the production of a result. accelerator ...
A growth-promoting “activity” released from activated platelets, the platelet-derived growth factor (PDGF), was discovered and characterized while investigating the cellular and molecular mechanisms underlying the formation of the ...


 -Derived Growth Factor (PDGF) & ReceptorFigure 4 : Metastasis: Metastasis to bone Figure 1: Platelet-Derived Growth Factor File:1PDG Platelet-DerivedGrowthFactorBb platelet-derived growth factor receptor Receptor, Epidermal Growth Factor; c-erbB




platelet-derived growth factor, PDGF
  • PDGF isoformはmitogen:cennective tissue cells, smooth muscle cells, and some epithelial and endothelial cell.
  • PDFG is thought to have a role in neoplastic transformation and tumor pathogenesis



  [★] 血小板由来成長因子

platelel-derived growth factor
platelet-derived growth factor



  • n.
  • 成長

WordNet   license wordnet

「(biology) the process of an individual organism growing organically; a purely biological unfolding of events involved in an organism changing gradually from a simple to a more complex level; "he proposed an indicator of osseous development in children"」
growing, maturation, development, ontogeny, ontogenesis

WordNet   license wordnet

「(pathology) an abnormal proliferation of tissue (as in a tumor)」

WordNet   license wordnet

「a progression from simpler to more complex forms; "the growth of culture"」

WordNet   license wordnet

「something grown or growing; "a growth of hair"」

WordNet   license wordnet

「vegetation that has grown; "a growth of trees"; "the only growth was some salt grass"」

PrepTutorEJDIC   license prepejdic

「〈U〉(…の)『成長』,発育;『発達』,発展《+『of』+『名』》 / 〈U〉(数・量,重要性・力などの)『増加』,増大,拡張《+『of』+『名』》 / 〈U〉《修飾語[句]を伴って》栽培,生産,…産 / 〈C〉成育した物,(草,木,髪,ひげなどの)生えたもの / 〈C〉腫瘍(しゅよう)」


  [★] 血小板

WordNet   license wordnet

「tiny bits of protoplasm found in vertebrate blood; essential for blood clotting」
blood platelet, thrombocyte