WordNet

xanthoma of the eyelids; occurs chiefly in the elderly

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/05/03 17:55:10」(JST)

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Treatment

Xanthelasmata can be removed with a trichloroacetic acid peel, surgery, lasers or cryotherapy. Removal can cause scarring and pigment changes, but it is unusual after treatment.

Name

The word is derived from Greek xanthos, ξανθός, "yellow" and έλασμα, elasma, "foil". The plural is xanthelasmata. Palpebrarum is Latin for 'of the eyebrows' (plural genitive case).^{[citation needed]}

Associations

A recent conference report — that is not yet published in a peer reviewed journal — claimed to show that the presence of Xanthelasma was associated with increased risk of heart attack of 51% and increased risk of ischemic heart disease of 40% ^[4]
Familial hypercholesterolemia^[1]
Primary biliary cirrhosis^[1]
Menopause^[1]
Diabetes^[1]

References

^ ^a ^b ^c ^d ^e ^f Lang, Gerhard K (2000). Ophthalmology. Stuttgart: Thieme. ^{[page needed]}
^ Shields, Carol; Shields, Jerry (2008). Eyelid, conjunctival, and orbital tumors: atlas and textbook. Hagerstwon, MD: Lippincott Williams & Wilkins. ISBN 0-7817-7578-7. ^{[page needed]}
^ "xanthelasma". Mosby's Medical Dictionary (8th ed.). 2009. Retrieved November 8, 2012.
^ Susman, Ed. "AHA: Eyelids Hold Clue to Heart Disease". Medpage Today. Retrieved 19 November 2013.

External links

treatment of xanthelasma with acid - pictures
xanthelasma removal
what is xanthelasma

UpToDate Contents

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1. 眼瞼の病変 eyelid lesions
2. LDLコレステロール代謝の主要な障害 primary disorders of ldl cholesterol metabolism
3. 原発性胆汁性肝硬変における高コレステロール血症およびアテローム性動脈硬化症 hypercholesterolemia and atherosclerosis in primary biliary cirrhosis
4. 内臓悪性腫瘍の皮膚症状 cutaneous manifestations of internal malignancy
5. 肝移植を受けた患者における皮膚障害 dermatologic problems in patients who have undergone liver transplantation

English Journal

Cerebrotendinous xanthomatosis in Spain: clinical, prognostic, and genetic survey.

Pilo-de-la-Fuente B, Jimenez-Escrig A, Lorenzo JR, Pardo J, Arias M, Ares-Luque A, Duarte J, Muniz-Perez S, Sobrido MJ.SourceDivision of Neurology, Hospital del Sureste, Ronda del Sur s/n, Arganda del Rey, Madrid, Spain Hospital Ramon y Cajal, Madrid, Spain Hospital Policlinico de Vigo, Vigo, Spain Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, Spain Complejo Asistencial de Leon, Leon, Spain Hospital General de Segovia, Spain Cegen, Grupo de Medicina Xenomica, Universidad de Santiago de Compostela, Spain Fundacion Publica Galega de Medicina Xenomica, Santiago de Compostela, Spain; Center for Network Research on Rare Disorders (CIBERER), Institute of Health Carlos III.
European journal of neurology : the official journal of the European Federation of Neurological Societies.Eur J Neurol.2011 Oct;18(10):1203-1211. doi: 10.1111/j.1468-1331.2011.03439.x. Epub 2011 Jun 4.
Background and purpose:? Cerebrotendinous xanthomatosis (CTX) is a rare autosomal recessive disorder caused by mutations in the CYP27A1 gene resulting in sterol-27-hydroxylase deficiency. Current information about CTX is based mainly on case reports, with only few large series reported. Although p
PMID 21645175

Insufficient bile acid signaling impairs liver repair in CYP27(-/-) mice.

Meng Z, Liu N, Fu X, Wang X, Wang YD, Chen WD, Zhang L, Forman BM, Huang W.SourceDivision of Gene Regulation and Drug Discovery, Beckman Research Institute, City of Hope National Medical Center, 1500 E. Duarte Road, Duarte, CA 91010, USA; Irell & Manella Graduate School of Biological Sciences, Beckman Research Institute, City of Hope National Medical Center, 1500 E. Duarte Road, Duarte, CA 91010, USA.
Journal of hepatology.J Hepatol.2011 Oct;55(4):885-95. Epub 2011 Feb 18.
BACKGROUND & AIMS: Previous studies indicate that bile acids (BAs) promote normal liver regeneration and repair after injury. However, the impact of insufficient BA signaling, which is observed in patients with BA sequestrant medication or cerebrotendinous xanthomatosis (CTX) disease, on liv
PMID 21334403