- xanthelasmaの複数形？
- 黄色腫 xanthelasma
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WordNet
- xanthoma of the eyelids; occurs chiefly in the elderly
UpToDate Contents
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- 1. 原発性胆汁性肝硬変における高コレステロール血症およびアテローム性動脈硬化症 hypercholesterolemia and atherosclerosis in primary biliary cirrhosis
English Journal
- Visible Age-Related Signs and Risk of Ischemic Heart Disease in the General Population: A Prospective Cohort Study.
- Christoffersen M, Frikke-Schmidt R, Schnohr P, Jensen GB, Nordestgaard BG, Tybjaerg-Hansen A.Author information Rigshospitalet; Copenhagen University Hospitals and Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.AbstractBACKGROUND: Cardiovascular disease is one of the most common age-related diseases, and also one of the most common causes of death in the general population. We tested the hypothesis that visible age-related signs associate with risk of ischemic heart disease (IHD), myocardial infarction (MI), and death in the general population, independent of chronological age.
- Circulation.Circulation.2013 Dec 13. [Epub ahead of print]
- BACKGROUND: Cardiovascular disease is one of the most common age-related diseases, and also one of the most common causes of death in the general population. We tested the hypothesis that visible age-related signs associate with risk of ischemic heart disease (IHD), myocardial infarction (MI), and d
- PMID 24334176
- Heterozygous familial hypercholesterolemia in Hong Kong Chinese. Study of 252 cases.
- Hu M, Lan W, Lam CW, Mak YT, Pang CP, Tomlinson B.Author information Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong.AbstractBACKGROUND: Earlier studies reported that Chinese subjects with heterozygous familial hypercholesterolemia (heFH) living in Mainland China or in Western countries had lower plasma low-density lipoprotein cholesterol (LDL-C) levels and lower prevalence of xanthomata or coronary heart disease (CHD) than Caucasians with heFH and a greater proportion went unrecognized. We characterized the features of Hong Kong Chinese with heFH identified by cascade screening.
- International journal of cardiology.Int J Cardiol.2013 Aug 10;167(3):762-7. doi: 10.1016/j.ijcard.2012.03.048. Epub 2012 Mar 30.
- BACKGROUND: Earlier studies reported that Chinese subjects with heterozygous familial hypercholesterolemia (heFH) living in Mainland China or in Western countries had lower plasma low-density lipoprotein cholesterol (LDL-C) levels and lower prevalence of xanthomata or coronary heart disease (CHD) th
- PMID 22464486
- First case report of familial hypercholesterolemia in an Omani family due to novel mutation in the low-density lipoprotein receptor gene.
- Al-Hinai AT, Al-Abri A, Al-Dhuhli H, Al-Waili K, Al-Sabti H, Al-Yaarubi S, Al-Hashmi K, Banerjee Y, Al-Zakwani I, Al-Rasadi K.Author information Department of Medicine, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman.AbstractFamilial hypercholesterolemia (FH) is an autosomal dominant genetic disorder. Mutations have been found in at least 3 genes: the low-density lipoprotein receptor (LDLR), apolipoprotein B (APOB), and proprotein convertase subtilisin/kexin type 9 (PCSK9). We report the first case of FH in an Omani family due to a novel mutation in the LDLR gene. A 9-year-old female was referred to our lipid clinic with eye xanthelasmata and thickening of both Achilles tendons. Evaluation of the lipid profile showed the off treatment total cholesterol of 896 mg/dL (23.2 mmol/L), low-density lipoprotein cholesterol (LDL-C) of 853 mg/dL (22.1 mmol/L), APOB of 4.5 g/L, triglyceride of 71 mg/dL (0.8 mmol/L), and high-density lipoprotein cholesterol of 0.74 mmol/L. Genetic analysis of the LDLR gene showed a homozygous frameshift deletion mutation (272delG) at exon 3. The female patient was treated with a combination of rosuvastatin/ezetimibe and LDL apheresis.
- Angiology.Angiology.2013 May;64(4):287-92. doi: 10.1177/0003319712465171. Epub 2012 Nov 15.
- Familial hypercholesterolemia (FH) is an autosomal dominant genetic disorder. Mutations have been found in at least 3 genes: the low-density lipoprotein receptor (LDLR), apolipoprotein B (APOB), and proprotein convertase subtilisin/kexin type 9 (PCSK9). We report the first case of FH in an Omani fam
- PMID 23162007
- Xanthelasmata, arcus corneae, and ischaemic vascular disease and death in general population: prospective cohort study.
- Christoffersen M, Frikke-Schmidt R, Schnohr P, Jensen GB, Nordestgaard BG, Tybjærg-Hansen A.Author information Department of Clinical Biochemistry, Rigshospitalet, DK-2100 Copenhagen, Denmark.AbstractOBJECTIVE: To test the hypothesis that xanthelasmata and arcus corneae, individually and combined, predict risk of ischaemic vascular disease and death in the general population.
- BMJ (Clinical research ed.).BMJ.2011 Sep 15;343:d5497. doi: 10.1136/bmj.d5497.
- OBJECTIVE: To test the hypothesis that xanthelasmata and arcus corneae, individually and combined, predict risk of ischaemic vascular disease and death in the general population.DESIGN: Prospective population based cohort study.SETTING: The Copenhagen City Heart Study.PARTICIPANTS: 12,745 people age
- PMID 21920887
Related Links
- [edit] Treatment. Xanthelasmata can be removed with a trichloroacetic acid peel, surgery, lasers or cryotherapy. Removal can cause scarring and pigment changes, but it is unusual after treatment with trichloroacetic acid.
- 17 Sep 2011 ... Xanthelasmata, patches of yellow skin around the lower or upper eyelids can mean that the person who has them has a greater risk of developing heart disease or having a heart attack, resear.
- 16 Sep 2011 ... A new study has identified a seemingly unlikely possible sign of an upcoming heart attack: a yellow, raised marking on the eyelid called xanthelasmata.
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