WordNet

the ordering of genes in a haploid set of chromosomes of a particular organism; the full DNA sequence of an organism; "the human genome contains approximately three billion chemical base pairs"
be a student; follow a course of study; be enrolled at an institute of learning
a room used for reading and writing and studying; "he knocked lightly on the closed door of the study"
applying the mind to learning and understanding a subject (especially by reading); "mastering a second language requires a lot of work"; "no schools offer graduate study in interior design" (同)work
a composition intended to develop one aspect of the performers technique; "a study in spiccato bowing"
a state of deep mental absorption; "she is in a deep study"
someone who memorizes quickly and easily (as the lines for a part in a play); "he is a quick study"
give careful consideration to; "consider the possibility of moving" (同)consider
learn by reading books; "He is studying geology in his room"; "I have an exam next week; I must hit the books now" (同)hit the books
think intently and at length, as for spiritual purposes; "He is meditating in his study" (同)meditate, contemplate
the act of consorting with or joining with others; "you cannot be convicted of criminal guilt by association"
(chemistry) any process of combination (especially in solution) that depends on relatively weak chemical bonding
a relation resulting from interaction or dependence; "flints were found in association with the prehistoric remains of the bear"; "the host is not always injured by association with a parasite"
the state of being connected together as in memory or imagination; "his association of his father with being beaten was too strong to break"
the process of bringing ideas or events together in memory or imagination; "conditioning is a form of learning by association" (同)connection, connexion
(ecology) a group of organisms (plants and animals) that live together in a certain geographical region and constitute a community with a few dominant species
a formal organization of people or groups of people; "he joined the Modern Language Association"
including all components without exception; being one unit or constituting the full amount or extent or duration; complete; "gave his whole attention"; "a whole wardrobe for the tropics"; "the whole hog"; "a whole week"; "the baby cried the whole trip home"; "a whole loaf of bread"
an assemblage of parts that is regarded as a single entity; "how big is that part compared to the whole?"; "the team is a unit" (同)unit
all of something including all its component elements or parts; "Europe considered as a whole"; "the whole of American literature"
(of siblings) having the same parents; "whole brothers and sisters"
provide with or construct with studs; "stud the wall"
ornament consisting of a circular rounded protuberance (as on a vault or shield or belt) (同)rivet
poker in which each player receives hole cards and the remainder are dealt face up; bets are placed after each card is dealt (同)stud poker
adult male horse kept for breeding (同)studhorse
a man who is virile and sexually active (同)he-man, macho-man

PrepTutorEJDIC

〈U〉(一般に)『勉強』,学習すること / 〈C〉(…の)勉強,研究《+of+名》 / 〈C〉〈U〉(…の)『綿密な調査』,検討《+of+名》 / 〈C〉研究対象(問題,事項);学科 / 〈C〉『書斎』,勉強部屋 / 〈C〉(美術・文学などの)習作,試作,スケッチ,(音楽の)練習曲,エチュード / …‘を'『勉強する』,学ぶ,研究する / …‘を'『よく注意して見る』,しげしげと見る / …‘を'『調査する』,検討する / …‘を'考慮する,配慮する / 〈せりふなど〉‘を'覚えようとする / 『勉強する』,学ぶ,研究する
〈U〉(…との)『交際』,付き合い《+『with』+『名』》 / 〈U〉(…との)『連合』,『共同』,関連《+『with』+『名』》 / 〈C〉組合,協会,会社 / 〈U〉連想;〈C〉《しばしば複数形で》連想されるもの
《the ~,one's ~ の形で名詞の前に用いて》『全体の』,全部の,全… / 《名詞の前にのみ用いて》(時間・距離などが)『まる』…,満… / (物が)完全な,欠けていない;《名詞の後に置いて》丸ごとで,ひとかたまりに / 《冠詞をつけずに複数名詞の前に用いて》ひじょうに多くの / 《古》(人が)無傷の,(肉体的に)健康な / 整数の,分数を含まない / 〈U〉《the ~》(…の)『全部』,全体,全量《+of+名》 / 〈C〉完全なもの,統一体
《おもに米》種馬 / 《集合的に》(一群の)繁殖用動物(種馬,種牛など)
(インテリアなどに用いる)飾りびょう / カフスボタン,カラーボタン / (建物の)間柱 / (…を)…‘に'ちりばめる《+名+with+名》 / …‘に'点在(散在)している / …‘に'間柱をつける

UpToDate Contents

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1. ゲノム疾患：概要 genomic disorders an overview
2. 遺伝学およびゲノミクスのためのツール：モデルシステム tools for genetics and genomics model systems
3. 遺伝学およびゲノミクスのためのツール：細胞遺伝学および分子遺伝学 tools for genetics and genomics cytogenetics and molecular genetics
4. 遺伝カウンセリングおよび遺伝子検査 genetic counseling and testing
5. 遺伝子検査における偶発的所見 incidental findings from genetic testing

English Journal

Integrated late onset Alzheimer's disease (LOAD) susceptibility genes: Cholesterol metabolism and trafficking perspectives.

Dong HK1, Gim JA2, Yeo SH3, Kim HS4.
Gene.Gene.2017 Jan 15;597:10-16. doi: 10.1016/j.gene.2016.10.022. Epub 2016 Oct 20.
Late onset Alzheimer's disease (LOAD) is the most common type of dementia and is characterized by decreased amyloid-β (Aβ) clearance from the brain. Cholesterol regulates the production and clearance of Aβ. Genome-wide association study (GWAS) suggests that at least 20 genes are associated with L
PMID 27773727

Pharmacogenetics of asthma: toward precision medicine.

Kersten ET1, Koppelman GH.
Current opinion in pulmonary medicine.Curr Opin Pulm Med.2017 Jan;23(1):12-20.
PURPOSE OF REVIEW: Although currently available drugs to treat asthma are effective in most patients, a proportion of patients do not respond or experience side-effects; which is partly genetically determined. Pharmacogenetics is the study of how genetic variations influence drug response. In this r
PMID 27764000

Japanese Journal

ポリジェニックリスクスコアを用いた糖尿病発症予測実用化の現実性 (特集糖尿病・肥満症に対するPrecision Medicine実現に向けて)

庄嶋伸浩,鈴木顕,細江隼,山内敏正,門脇孝
内分泌・糖尿病・代謝内科 = Endocrinology, diabetology & metabolism 49(5), 351-357, 2019-11
NAID 40022067705

糖尿病患者の薬剤効果予測に遺伝情報をどう活かすか (特集 1,000万通りの糖尿病個別化医療に向けた遺伝情報の活用の仕方)

庄嶋伸浩,山内敏正,鈴木顕,細江隼,門脇孝
内分泌・糖尿病・代謝内科 = Endocrinology, diabetology & metabolism 48(3), 206-213, 2019-03
NAID 40021856365

POGLUT1, the putative effector gene driven by rs2293370 in primary biliary cholangitis susceptibility locus chromosome 3q13.33

Hitomi Yuki,Ueno Kazuko,Kawai Yosuke,Nishida Nao,Kojima Kaname,Kawashima Minae,Aiba Yoshihiro,Nakamura Hitomi,Kouno Hiroshi,Kouno Hirotaka,Ohta Hajime,Sugi Kazuhiro,Nikami Toshiki,Yamashita Tsutomu,Katsushima Shinji,Komeda Toshiki,Ario Keisuke,Naganuma Atsushi,Shimada Masaaki,Hirashima Noboru,Yoshizawa Kaname,Makita Fujio,Furuta Kiyoshi,Kikuchi Masahiro,Naeshiro Noriaki,Takahashi Hironao,Mano Yutaka,Yamashita Haruhiro,Matsushita Kouki,Tsunematsu Seiji,Yabuuchi Iwao,Nishimura Hideo,Shimada Yusuke,Yamauchi Kazuhiko,Komatsu Tatsuji,Sugimoto Rie,Sakai Hironori,Mita Eiji,Koda Masaharu,Nakamura Yoko,Kamitsukasa Hiroshi,Sato Takeaki,Nakamuta Makoto,Masaki Naohiko,Takikawa Hajime,Tanaka Atsushi,Ohira Hiromasa,Zeniya Mikio,Abe Masanori,Kaneko Shuichi,Honda Masao,Arai Kuniaki,Arinaga-Hino Teruko,Hashimoto Etsuko,Taniai Makiko,Umemura Takeji,Joshita Satoru,Nakao Kazuhiko,Ichikawa Tatsuki,Shibata Hidetaka,Takaki Akinobu,Yamagiwa Satoshi,Seike Masataka,Sakisaka Shotaro,Takeyama Yasuaki,Harada Masaru,Senju Michio,Yokosuka Osamu,Kanda Tatsuo,Ueno Yoshiyuki,Ebinuma Hirotoshi,Himoto Takashi,Murata Kazumoto,Shimoda Shinji,Nagaoka Shinya,Abiru Seigo,Komori Atsumasa,Migita Kiyoshi,Ito Masahiro,Yatsuhashi Hiroshi,Maehara Yoshihiko,Uemoto Shinji,Kokudo Norihiro,Nagasaki Masao,Tokunaga Katsushi,Nakamura Minoru
Scientific reports (9), 2019-01-14
… Our previous genome-wide association study (GWAS) identified six susceptibility loci for PBC. …
NAID 120006715480

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