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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/09/18 14:51:21」(JST)

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1. 過敏性腸症候群に対するアロセトロン塩酸塩（Lotronex） alosetron hydrochloride lotronex for irritable bowel syndrome
2. 変形性関節症の初回薬物療法 initial pharmacologic therapy of osteoarthritis
3. クリンダマイシン：概要 clindamycin an overview
4. 成人における急性咽頭炎の対症療法 symptomatic treatment of acute pharyngitis in adults
5. 慢性非アレルギー性鼻炎 chronic nonallergic rhinitis

A Prospective Randomized Trial to Compare the Efficacy of Tramazoline and Cocaine for Nasal Vasoconstriction before Nasal Surgery.

Zhang JX1, Li ZY1, Zhao L1, Li G1, Cao GL1, Zhang CY1.
Drug research.Drug Res (Stuttg).2014 Sep 4. [Epub ahead of print]
Background: To provide the vasoconstriction required for nasal surgery cocaine is frequently used topically; nevertheless, it has been accompanying with intraoperative cardiac adverse effects. In the present study, tramazoline was compared with cocaine as a substitute to determine their proportional
PMID 25188610

The effect of nasal tramazoline with dexamethasone in obstructive sleep apnoea patients.

Koutsourelakis I1, Minaritzoglou A, Zakynthinos G, Vagiakis E, Zakynthinos S.
The European respiratory journal.Eur Respir J.2013 Oct;42(4):1055-63. doi: 10.1183/09031936.00142312. Epub 2013 Feb 8.
Although there is a strong correlation between oral/oro-nasal breathing and apnoea/hypopnoea index in patients with obstructive sleep apnoea and normal nasal resistance at wakefulness, it remains unknown whether the pharmacological prevention of potential nasal obstruction during sleep could decreas
PMID 23397296

Study and development of reversed-phase HPLC systems for the determination of 2-imidazolines in the presence of preservatives in pharmaceutical preparations.

Antoniou CG1, Markopoulou CK, Kouskoura MG, Koundourellis JE.
Journal of AOAC International.J AOAC Int.2011 May-Jun;94(3):703-12.
Different HPLC chromatographic systems were investigated on a C18 ACE 5 pm, 150 x 4.6 mm id column for the determination of tymazoline, tramazoline, and antazoline, with either naphazoline or xylometazoline, in commercial preparations. For the development and optimization of the systems, a Response
PMID 21796997

竹野幸夫,平田したう,平川勝洋,夜陣紘治,川本浩子
日本鼻科学会会誌 38(2), 223-229, 1999
… In this prospective study, we investigated changes to nasal airway patency in the immediate response to the topical nasal decongestant, tramazoline hydrochloride, in patients with various nasal diseases. … The pharmacological effect of tramazoline seems to depend on the anatomical features of the nasal cavity, aging, and the pathological changes to the nasal mucosa as well as therapeutic effects against nose diseases. …
NAID 130003720609

Tramazoline
Systematic (IUPAC) name
	N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine
Clinical data
AHFS/Drugs.com	International Drug Names
Legal status	?
Identifiers
CAS number	1082-57-1
ATC code	R01AA09
PubChem	CID 5524
UNII	SLE31693IV
ChEMBL	CHEMBL32573
Chemical data
Formula	C13H17N3
Mol. mass	215.294 g/mol
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