トラマゾリン
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/02/12 15:37:32」(JST)
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This article is incomplete. Please help to improve it, or discuss the issue on the talk page. (January 2015) |
Tramazoline
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Systematic (IUPAC) name |
N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine
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Clinical data |
AHFS/Drugs.com |
International Drug Names |
Identifiers |
CAS Number |
1082-57-1 N |
ATC code |
R01AA09 |
PubChem |
CID 5524 |
UNII |
SLE31693IV Y |
ChEMBL |
CHEMBL32573 N |
Chemical data |
Formula |
C13H17N3 |
Molar mass |
215.294 g/mol |
NY (what is this?) (verify) |
Tramazoline is a chemical that is used in the form of tramazoline hydrochloride in nasal decongestant preparations. [1] It is an α-adrenergic receptor agonist that inhibits secretion of nasal mucus.
It causes hypertension.[2]
Product names
Australia
Austria
Belgium
Czech Republic
Germany
- Biciron
- Ellatun
- Rhinospray
Italy
Romania
- Muconasal Plus (older)
- Muconasal (newer)
Russia
Spain
Slovakia
Ukraine
References
- ^ "Spray-Tish Consumer Information". Consumer Medicines Information. MyDr.com.au. Retrieved 16 April 2011.
- ^ Peng N, Meng QC, King K, Oparil S, Wyss JM (April 1995). "Acute hypertension increases norepinephrine release in the anterior hypothalamic area". Hypertension 25 (4 Pt 2): 828–33. doi:10.1161/01.hyp.25.4.828. PMID 7721439.
- ^ "Spray-Tish". Consumer Information. Retrieved 16 April 2011.
Decongestants and other nasal preparations (R01)
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Topical |
Sympathomimetics, plain
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- Cyclopentamine
- Ephedrine
- Epinephrine
- Fenoxazoline
- Levomethamphetamine
- Metizoline
- Naphazoline
- Oxymetazoline
- Phenylephrine
- Propylhexedrine
- Tetryzoline
- Tramazoline
- Tuaminoheptane
- Tymazoline
- Xylometazoline
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Antiallergic agents,
excluding corticosteroids
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- histamine antagonists (Levocabastine
- Antazoline
- Thonzylamine)
- mast cell stabilizer (some are also antihistamines) (Cromoglicic acid
- Nedocromil
- Azelastine
- Olopatadine
- Lodoxamide)
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Corticosteroids
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- Beclometasone dipropionate
- Betamethasone
- Budesonide
- Ciclesonide
- Dexamethasone
- Flunisolide
- Fluticasone
- Mometasone furoate
- Prednisolone
- Tixocortol
- Triamcinolone
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Other nasal preparations
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- Cafaminol
- Calcium hexamine thiocyanate
- Eucalyptus oil
- Framycetin
- Hexamidine
- Hyaluronan
- Ipratropium bromide
- Mupirocin
- Retinol
- Ritiometan
- Saline water
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Systemic use:
Sympathomimetics |
- Phenylephrine
- Phenylpropanolamine
- Phenylpropylamine
- Pseudoephedrine (+loratadine)
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English Journal
- Retraction. A Prospective Randomized Trial to Compare the Efficacy of Tramazoline and Cocaine for Nasal Vasoconstriction before Nasal Surgery.
- Zhang JX1, Li ZY1, Zhao L1, Li G1, Cao GL1, Zhang CY1.
- Drug research.Drug Res (Stuttg).2015 Dec;65(12):672. doi: 10.1055/s-0034-1387769. Epub 2014 Sep 4.
- J.-X. Zhang, Z.-Y. Li, L. Zhao, G. Li, G.-L. Cao, C.-Y. Zhang are retracting their paper, entitled A Prospective Randomized Trial to Compare the Efficacy of Tramazoline and Cocaine for Nasal Vasoconstriction before Nasal Surgery [Drug Res 2014, epub ahead of print. September 4, 2014], claiming lack
- PMID 25188610
- Treatment of acute rhinitis with a nasal spray containing tramazoline and essential oils: a multicenter, uncontrolled, observational trial.
- Katona G1, Sultész M1, Farkas Z1, Gyimesi A2, Hirschberg A2, Huszka J3, Radvánszky F3, Simon Á3, Fülöp G3, Láng J3, Ablonczy M4, Nirnberger G5, Holm C6.
- Clinical and translational allergy.Clin Transl Allergy.2015 Nov 4;5:38. doi: 10.1186/s13601-015-0084-5. eCollection 2015.
- BACKGROUND: In this observational trial, data were collected on the effectiveness and tolerability/safety of a nasal spray containing tramazoline and essential oils (trade name Rhinospray(®) Plus) used for symptomatic treatment of acute rhinitis due to common cold.METHODS: The trial was performed i
- PMID 26539289
- The effect of nasal tramazoline with dexamethasone in obstructive sleep apnoea patients.
- Koutsourelakis I1, Minaritzoglou A, Zakynthinos G, Vagiakis E, Zakynthinos S.
- The European respiratory journal.Eur Respir J.2013 Oct;42(4):1055-63. doi: 10.1183/09031936.00142312. Epub 2013 Feb 8.
- Although there is a strong correlation between oral/oro-nasal breathing and apnoea/hypopnoea index in patients with obstructive sleep apnoea and normal nasal resistance at wakefulness, it remains unknown whether the pharmacological prevention of potential nasal obstruction during sleep could decreas
- PMID 23397296
Japanese Journal
- acoustic rhinometryを用いた鼻処理効果の評価-通年性鼻アレルギー症例と正常例の比較-
- 竹野 幸夫,川本 浩子,平田 したう,福島 典之,夜陣 紘治
- 日本耳鼻咽喉科學會會報 101(7), 900-907, 1998-07-20
- … In this prospective clinical study, we investigated the effect of the nasal decongestant tramazoline on nasal airway patency in 30 subjects with perennial nasal allergy to housedust mites and in six non-allergic volunteers who served as controls. …
- NAID 10005598313
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★リンクテーブル★
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- 英
- tramazoline
- 化
- 塩酸トラマゾリン tramazoline hydrochloride
- 商
- トーク
[★]
トラマゾリン。塩酸トラマゾリン