thyrotropin receptor-stimulating antibodies

同

TRSAbs

WordNet

1. a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
2. rousing or quickening activity or the senses; "a stimulating discussion"
3. anterior pituitary hormone that stimulates the function of the thyroid gland (同)thyrotropic hormone, thyrotrophin, thyrotrophic hormone, thyroid-stimulating_hormone, TSH

PrepTutorEJDIC

1. =sense organ / 受信装置
2. 刺激する;激励する,元気づける

UpToDate Contents

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• 1. 橋本病（慢性自己免疫性甲状腺炎）の病因 pathogenesis of hashimotos thyroiditis chronic autoimmune thyroiditis
• 2. 小児および思春期における甲状腺機能亢進症の臨床症状および診断 clinical manifestations and diagnosis of hyperthyroidism in children and adolescents
• 3. 甲状腺機能亢進症の原因となる疾患 disorders that cause hyperthyroidism
• 4. バセドウ病（グレーブス病）の発症機序 pathogenesis of graves disease
• 5. 甲状腺機能亢進症の診断 diagnosis of hyperthyroidism

English Journal

• The negative correlation between thyrotropin receptor-stimulating antibodies and bone mineral density in postmenopausal patients with Graves' disease.

• Amashukeli M1, Korinteli M, Zerekidze T, Jikurauli N, Shanava S, Tsagareli M, Giorgadze E.
• Journal of investigative medicine : the official publication of the American Federation for Clinical Research.J Investig Med.2013 Jun;61(5):842-7. doi: 10.231/JIM.0b013e31828fcafb.
• Graves' disease is an autoimmune disorder with various clinical manifestations. Thyrotropin receptor antibodies (TRAbs), the circulating autoantibodies specific to Graves' disease, are the cause for hyperthyroidism, the most prevalent abnormality. Hyperthyroidism leads to increased bone turnover and
• PMID 23612147

• Circulating IgGs may modulate IGF-I receptor stimulating activity in a subset of patients with Graves' ophthalmopathy.

• Varewijck AJ1, Boelen A, Lamberts SW, Fliers E, Hofland LJ, Wiersinga WM, Janssen JA.
• The Journal of clinical endocrinology and metabolism.J Clin Endocrinol Metab.2013 Feb;98(2):769-76. doi: 10.1210/jc.2012-2270. Epub 2013 Jan 7.
• CONTEXT: There is a close association between levels of TSH binding inhibitory immunoglobulins (TBIIs) and Graves' ophthalmopathy (GO). In addition to the TSH receptor, the IGF-I receptor (IGF-IR) has been proposed to be a second autoantigen that plays a role in the pathogenesis of GO.OBJECTIVE: The
• PMID 23295466

• Genetically driven target tissue overexpression of CD40: a novel mechanism in autoimmune disease.

• Huber AK1, Finkelman FD, Li CW, Concepcion E, Smith E, Jacobson E, Latif R, Keddache M, Zhang W, Tomer Y.
• Journal of immunology (Baltimore, Md. : 1950).J Immunol.2012 Sep 15;189(6):3043-53. doi: 10.4049/jimmunol.1200311. Epub 2012 Aug 10.
• The CD40 gene, an important immune regulatory gene, is also expressed and functional on nonmyeloid-derived cells, many of which are targets for tissue-specific autoimmune diseases, including β cells in type 1 diabetes, intestinal epithelial cells in Crohn's disease, and thyroid follicular cells in
• PMID 22888137

Japanese Journal

• Monoclonal antibodies to the thyrotropin receptor : stimulating and blocking antibodies derived from the lymphocytes of patients with Graves' disease

• VALENTE WA.
• Proc Natl Acad Sci USA 79, 6680-6684, 1982
• NAID 30016273451

Related Links

• THYRO - Overview: Thyrotropin Receptor Antibody, Serum

THYRO : Recommended first-line test for detection of thyrotropin receptor (TSHR) antibodies, and used in the following situations: -Differential diagnosis of etiology of thyrotoxicosis in patients with ambiguous clinical findings and/or ...

• Thyrotropin receptor antibody is a test for Graves disease ...

Thyrotropin Receptor Antibody Details Last Update On : 2014-02-09 All forms of autoimmune thyrotoxicosis (Graves disease, Hashitoxicosis, neonatal thyrotoxicosis) are caused by the production of TSHR-stimulating autoantibody ...

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★リンクテーブル★

リンク元	「TRSAbs」
関連記事	「stimulating」「thyrotropin receptor」「thyrotropin」

「TRSAbs」

　　[★]

同

thyrotropin receptor-stimulating antibodies

「stimulating」

　　[★]

• adj.

• 刺激的な

関

exciting、irritant

　 　

「thyrotropin receptor」

　　[★] 甲状腺刺激ホルモン受容体

「thyrotropin」

　　[★] 甲状腺刺激ホルモン