WordNet

a blood disease characterized by an abnormally small number of platelets in the blood (同)thrombopenia
any of several blood diseases causing subcutaneous bleeding (同)peliosis

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Fulminant thrombotic thrombocytopenic purpura (TTP): association with amphetamine consumption?

de Fallois J1, Regenthal R, Petros S.
Annals of hematology.Ann Hematol.2015 Feb;94(2):337-8. doi: 10.1007/s00277-014-2125-x. Epub 2014 Jun 4.
PMID 24894160

Relationship between ADAMTS13 activity, von Willebrand factor antigen levels and platelet function in the early and late phases after TIA or ischaemic stroke.

McCabe DJ1, Murphy SJ2, Starke R3, Harrison P4, Brown MM5, Sidhu PS5, Mackie IJ3, Scully M6, Machin SJ7.
Journal of the neurological sciences.J Neurol Sci.2015 Jan 15;348(1-2):35-40. doi: 10.1016/j.jns.2014.10.035. Epub 2014 Oct 31.
BACKGROUND: Reduced ADAMTS13 activity is seen in thrombotic thrombocytopenic purpura (TTP), and may lead to accumulation of prothrombotic ultra-large von Willebrand factor (ULVWF) multimers in vivo. ADAMTS13 activity and its relationship with VWF antigen (VWF:Ag) levels and platelet function in 'non
PMID 25498844

Zheng XL1.
Annual review of medicine.Annu Rev Med.2015 Jan 14;66:211-25. doi: 10.1146/annurev-med-061813-013241.
Pathogenesis of thrombotic thrombocytopenic purpura (TTP) was a mystery for over half a century until the discovery of ADAMTS13. ADAMTS13 is primarily synthesized in the liver, and its main function is to cleave von Willebrand factor (VWF) anchored on the endothelial surface, in circulation, and at
PMID 25587650

Renal thrombotic microangiopathies/thrombotic thrombocytopenic purpura in a patient with primary Sjögren's syndrome complicated with IgM monoclonal gammopathy of undetermined significance.

Koga Tomohiro,Yamasaki Satoshi,Nakamura Hideki,Kawakami Atsushi,Furusu Akira,Taguchi Takashi,Eguchi Katsumi
Rheumatology international 33(1), 227-230, 2013-01-00
… Thrombotic microangiopathy (TMA)/thrombotic thrombocytopenic purpura (TTP) is a rare but potentially lethal condition requiring rapid recognition, diagnosis, and initiation of therapy. … She was admitted to our hospital for further evaluation of hypergammaglobulinema, acute renal failure, and severe thrombocytopenia. …
NAID 120002383501

Drug-induced Thrombotic Thrombocytopenic Purpura Successfully Treated with Recombinant Human Soluble Thrombomodulin

Nishijima Yu,Hirata Haruhiko,Himeno Aiko,Kida Hiroshi,Matsumoto Masanori,Takahashi Ryo,Otani Yasushi,Inoue Kouji,Nagatomo Izumi,Takeda Yoshito,Kijima Takashi,Tachibana Isao,Fujimura Yoshihiro,Kumanogoh Atsushi
Internal Medicine 52(10), 1111-1114, 2013
… A 61-year-old woman with recurrent non-small cell lung cancer presented with thrombocytopenia, microangiopathic hemolytic anemia, neurological abnormalities, renal failure and a fever that appeared during chemotherapy with gemcitabine and bevacizumab. … She was diagnosed with drug-induced thrombotic thrombocytopenic purpura (TTP). …
NAID 130003365599

石西綾美,早川正樹,松本雅則,八木秀男,藤村吉博
日本アフェレシス学会雑誌 31(1), 7-13, 2012-02-29
… Thrombotic thrombocytopenic purpura (TTP) is a life-threatening generalized disease featured by a 'classic pentad' consisting of hemolytic anemia, thrombocytopenia, renal dysfunction, fever, and fluctuating neurological signs. … On the other hand, hemolytic-uremic syndrome (HUS) with prominent nephrological signs is often indistinguishable from TTP, because both the diseases have common pathological conditions termed thrombotic microangiopathies. …
NAID 110009327447