WordNet

relating to or characterized by suppuration
inflammation of lymph nodes

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1. 小児における頸部リンパ節炎：診断的アプローチおよび初期治療 cervical lymphadenitis in children diagnostic approach and initial treatment
2. 深頸部の感染症 deep neck space infections
3. 成人における末梢リンパ節腫大の評価 evaluation of peripheral lymphadenopathy in adults
4. 小児における末梢のリンパ節腫脹：評価および診断的アプローチ peripheral lymphadenopathy in children evaluation and diagnostic approach
5. 小児における非結核性抗酸菌性リンパ節炎の概要 overview of nontuberculous mycobacterial lymphadenitis in children

English Journal

Tularemia: potential role of cytopathology in differential diagnosis of cervical lymphadenitis: multicenter experience in 53 cases and literature review.

Tuncer E1, Onal B, Simsek G, Elagoz S, Sahpaz A, Kilic S, Altuntas EE, Ulu Kilic A.Author information 1Pathology Department, Faculty of Medicine, Cumhuriyet University, Sivas, Turkey.AbstractTularemia is a zoonosis caused by Francisella tularensis. Tularemia outbreaks occurred in Central Anatolia during 2009 and 2011. We evaluated the clinical characteristics and cytomorphologies of fine needle aspirations (FNAs) from cervical lymph nodes in serologically confirmed tularemia cases. To our knowledge, this is the first large series concerning FNA morphology of Tularemia. FNA smears of 53 patients of the 290, diagnosed by microagglutination tests and PCR, were evaluated at three Pathology centers. FNAs were performed by cytopathologists or ear-nose-throat surgeons. Of all patients, 17 had also lymph node resections. FNAs showed the presence of suppuration and abscess. Rare epithelioid histiocytes and granulomas, seldom phagocytosed bacilli-like microorganisms were observed. On histopathology; granulomas, necrosis, and suppurative inflammation extending extracapsular areas were seen. Tularemia is endemic in certain areas of the Northern Hemisphere. The benefit from cytopathology is limited and cytological suspicion should be confirmed by serology. However FNA cytology is helpful in differential diagnosis of tularemia and other diseases presented with suppurative, granulomatous cervical lymphadenitis. It is also useful in providing the material for PCR and culture in early phase when the serology is negative and the treatment is more effective.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.APMIS.2014 Mar;122(3):236-42. doi: 10.1111/apm.12132. Epub 2013 Jun 14.
Tularemia is a zoonosis caused by Francisella tularensis. Tularemia outbreaks occurred in Central Anatolia during 2009 and 2011. We evaluated the clinical characteristics and cytomorphologies of fine needle aspirations (FNAs) from cervical lymph nodes in serologically confirmed tularemia cases. To o
PMID 23763361

Nodular sclerosing classical Hodgkin lymphoma masquerading as acute suppurative-necrotizing lymphadenitis.

Florentine BD1, Cohen AN.Author information 1FNA Specialists of the Valley, Valley Village, California; Department of Pathology, Keck School of Medicine, University of Southern California, California.AbstractThe diagnosis of nodular sclerosing classical Hodgkin lymphoma (NSCHL) by fine-needle aspiration (FNA) biopsy has historically been a diagnostic challenge due to the usual paucicellularity of the specimen. This case report, and other previously published reports, suggests that there is another facet to the potentially challenging diagnosis of this particular variant of Hodgkin lymphoma (HL): the presence of suppurative-necrotizing changes mimicking an infectious etiology. The patient presented here underwent FNA biopsy of an acutely enlarged supraclavicular lymph node and cytologic smears showed marked acute inflammation in a background of necrosis. A diagnosis of infectious suppurative lymphadenitis was made at that time. After a negative infectious work-up with infectious disease consultation, an excisional biopsy was performed and the patient was definitively diagnosed with NSCHL. The presence of neoplastic Hodgkin and Reed-Sternberg cells in the purulent exudate was minimal and only appropriately identified after retrospective review. This particular subtype of classical HL represents a potential pitfall in FNA biopsy cytology. Consequently, the cytopathologist and surgeon should always consider this entity in the differential diagnosis of a suppurative, lymphadenitis-like aspirate, and pursue repeat FNA or an excisional biopsy if there is any clinical index of suspicion.
Diagnostic cytopathology.Diagn Cytopathol.2014 Mar;42(3):238-41. doi: 10.1002/dc.21829. Epub 2011 Sep 30.
The diagnosis of nodular sclerosing classical Hodgkin lymphoma (NSCHL) by fine-needle aspiration (FNA) biopsy has historically been a diagnostic challenge due to the usual paucicellularity of the specimen. This case report, and other previously published reports, suggests that there is another facet
PMID 21965120

Lymph nodes cytology in HIV seropositive cases with haematological alterations.

Tirumalasetti N1, Latha PP.Author information 1Department of Pathology, NRI Medical College, Chinakakani, Guntur, Andhra Pradesh, India.AbstractBackground & objectives: Lymphadenopathy and haematological alterations are the earliest manifestations with other associated opportunistic infections and malignancies. Hence, there is a need for simple investigations like fine needle aspiration cytology (FNAC) for evaluation of HIV lymphadenopathy and a haemogram to interpret the haematological alterations. This study was undertaken to analyze the cytological patterns of lymph node lesions in HIV/AIDS patients, to compare with available clinico-pathological and haematological parameters to segregate lymphadenopathy cases for further evaluation. Methods: In the present study, 129 HIV seropositive patients were included. Lymph node aspirates were stained routinely with hematoxylin and eosin and Ziehl-Neelsen (Z-N) stains. Special stains and cultures were done in selected patients. Peripheral smears were taken from all the patients and CD4 counts were recorded. Tuberculous lymphadenitis was further categorized. Acid fast bacilli (AFB) grading was done on Z-N positive smears. Each lesion was compared with CD4 counts, WHO clinical staging and haematological picture. Results: Cytological diagnosis in 129 patients included tuberculous (n=54, 41.9%), reactive lymphadenopathy (n=46, 35.6%), suppurative (n=16, 12.4%) lymphadenitis, non-Hodgkin's lymphoma (n=4, 3.1%), and Hodgkin's lymphoma, secondary deposits, other granulomatous lesions, and cryptoccocal lymphadenitis in one patient each. The predominant cytomorphological pattern in tuberculous lymphadenitis was caseous necrosis + epithelioid granuloma formation (51.85%). Grade 2+ Z-N grading was noted in 62.96 per cent of AFB positive smears. CD4 counts showed a descending pattern with progression of WHO clinical staging. Cytopenia was more common in WHO clinical stage IV disease. Interpretation & conclusions: Lymph node cytology was found to be a useful tool for segregating lymphadenopathy cases for further evaluation and for identification of opportunistic infections, neoplastic and non-neoplastic lesions. Comparison of lymph node lesions with CD4 counts, WHO clinical staging, haematological alterations and AFB grading reflects immunity, stage of disease and disease activity aiding better treatment.
The Indian journal of medical research.Indian J Med Res.2014 Feb;139(2):301-7.
Background & objectives: Lymphadenopathy and haematological alterations are the earliest manifestations with other associated opportunistic infections and malignancies. Hence, there is a need for simple investigations like fine needle aspiration cytology (FNAC) for evaluation of HIV lymphadenopa
PMID 24718407

Japanese Journal

Granulomatous Lymphadenitis

ASANO Shigeyuki
Journal of clinical and experimental hematopathology 52(1), 1-16, 2012-05-01
… In this review, representative types of granulomatous lymphadenitis (GLA) are described. … Infectious GLA can be classified as suppurative lymphadenitis (LA) and nonsuppurative LA. … Suppurative LA generally shows follicular hyperplasia and sinus histiocytosis in the early phase. …
NAID 10030615424