WordNet

relating to or characterized by suppuration
cause to ripen and discharge pus; "The oil suppurates the pustules" (同)mature
symptom of being purulent (containing or forming pus) (同)purulency
producing pus
not suppurative

PrepTutorEJDIC

〈傷が〉うむ,化膿する
化膿;うみ
うみ,化膿

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/04/21 18:14:15」(JST)

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For other uses, see Pus (disambiguation).

Eye with conjunctivitis exuding pus

An abscess is an enclosed collection of pus

Duodenoscopy image of hepatopancreatic ampulla with pus extruding from it, indicative of cholangitis

Pus is an exudate, typically white-yellow, yellow, or yellow-brown, formed at the site of inflammation during infection.^[1] An accumulation of pus in an enclosed tissue space is known as an abscess, whereas a visible collection of pus within or beneath the epidermis is known as a pustule or pimple.

Pus consists of a thin, protein-rich fluid, known as liquor puris, and dead leukocytes from the body's immune response (mostly neutrophils). During infection, macrophages release cytokines which trigger neutrophils to seek the site of infection by chemotaxis. There, the neutrophils engulf and destroy the bacteria and the bacteria resist the immune response by releasing toxins called leukocidins.^[2] As the neutrophils die off from toxins and old age, they are destroyed by macrophages, forming the viscous pus.

Bacteria that cause pus are called suppurative, pyogenic,^[2]^[3] or purulent. If the agent also creates mucus, it is called mucopurulent.

Despite normally being of a whitish-yellow hue, changes in the color of pus can be observed under certain circumstances. Pus is sometimes green because of the presence of myeloperoxidase, an intensely green antibacterial protein produced by some types of white blood cells. Green, foul-smelling pus is found in certain infections of Pseudomonas aeruginosa. The greenish color is a result of the bacterial pigment pyocyanin that it produces. Amoebic abscesses of the liver produce brownish pus, which is described as looking like "anchovy paste". Pus can also have a foul odor, particularly pus from anaerobic infections.^[4]

In almost all cases when there is a collection of pus in the body, the clinician will try to create an opening for it to evacuate - this principle has been distilled into the famous Latin aphorism "Ubi pus, ibi evacua"

Some common disease processes caused by pyogenic infections are impetigo, osteomyelitis, septic arthritis, and necrotizing fasciitis.^[5]^{[not in citation given]}

Pyogenic bacteria

A great many species of bacteria may be pyogenic. The most commonly found include:^[6]^{[unreliable medical source?]}

Staphylococcus aureus
Staphylococcus epidermidis
Streptococcus pyogenes
Escherichia coli (Bacillus coli communis)
Streptococcus pneumoniae (Fraenkel's pneumococcus)
Klebsiella pneumoniae (Friedländer's bacillus)
Salmonella typhi (Bacillus typhosus)
Pseudomonas aeruginosa
Neisseria gonorrhoeae
Actinomyces
Burkholderia mallei (Glanders bacillus)
Mycobacterium tuberculosis (tubercle bacillus)

References

^ "Pus - Definitions from Dictionary.com". reference.com. Retrieved 2008-08-18.
^ ^a ^b Madigan, Michael T. and Martin, John M. Brock Biology of Microorganisms 11th ed. Pearson Prentice Hall. USA. 2006: 734
^ "pyogenic" at Dorland's Medical Dictionary
^ Topazian RG, Goldberg MH, Hupp JR (2002). Oral and maxillofacial infections (4 ed.). Philadelphia: W.B. Saunders. ISBN 978-0721692715.
^ "Infections Caused by Common Pyogenic Bacteria", Dermatopathology (Springer Berlin Heidelberg): 83–85, doi:10.1007/3-540-30244-1_12
^ Thompson, Alexis; Miles, Alexander (1921). "Pyogenic Bacteria". Manual of Surgery (6th ed.). Oxford Medical Publications. OCLC 335390813.

UpToDate Contents

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1. 成人における急性中耳炎（化膿性および漿液性） acute otitis media in adults suppurative and serous
2. 化膿性（敗血症性）血栓性静脈炎 suppurative septic thrombophlebitis
3. 成人における慢性中耳炎、真珠腫、および乳様突起炎 chronic otitis media cholesteatoma and mastoiditis in adults
4. 深頸部の感染症 deep neck space infections
5. 小児および思春期における化膿性甲状腺炎 suppurative thyroiditis in children and adolescents

English Journal

Patients with hidradenitis suppurativa carry a higher systemic inflammatory load than other dermatological patients.

Riis PT1, Søeby K2, Saunte DM3, Jemec GB3.
Archives of dermatological research.Arch Dermatol Res.2015 Dec;307(10):885-9. doi: 10.1007/s00403-015-1596-5. Epub 2015 Sep 9.
Hidradenitis is a chronic inflammatory skin disease with recurrent nodules, tunnels, scarring and suppuration of intertrigious areas. Hospital-treated HS patients have an increased risk of metabolic syndrome and a wide array of co-morbidities that possibly are related to systemic inflammation. Neutr
PMID 26350517

Polymorphisms in Toll-like receptors 2 and 4 genes and their expression in chronic suppurative otitis media.

Jotic A1, Jesic S2, Zivkovic M3, Tomanovic N4, Kuveljic J3, Stankovic A3.
Auris, nasus, larynx.Auris Nasus Larynx.2015 Dec;42(6):431-7. doi: 10.1016/j.anl.2015.04.010. Epub 2015 Jun 6.
OBJECTIVE: Toll-like receptors (TLRs) have a prominent role in inducing innate immune response. It has been suggested that regulation of TLRs is involved in the pathogenesis of chronic otitis media. TLR 2 and TLR 4 polymorphisms were connected with susceptibility to acute otitis and chronic otitis w
PMID 26055429

Primary abdominal wall actinomycosis.

Karaca B1, Tarakci H2, Tumer E2, Calik S3, Sen N4, Sivrikoz ON5.
Hernia : the journal of hernias and abdominal wall surgery.Hernia.2015 Dec;19(6):1015-8. doi: 10.1007/s10029-013-1208-2. Epub 2014 Jan 4.
PURPOSE: Actinomycosis is a progressive, chronic, granulomatous and suppurative disease caused by different types of actinomyces. Instead of chronic suppurative disease, sinus formation can also be seen. Cervicofascial, abdominal and thoracal involvement can occur. Abdominal wall actinomycosis is an
PMID 24389631

Japanese Journal

膀胱癌に対するBCG膀胱内注入療法後に発症した結核性精巣上体炎の1例

上阪裕香,高比優子,伊藤伸一郎,木内寛,市丸直嗣
泌尿器科紀要 58(2), 113-116, 2012-02
… Treatment with levofloxacin for acute epididymitis reduced the scrotal pain initially, but the pain increased and 3 months later, a fistula with suppurative discharge appeared at the bottom of the scrotum. …
NAID 120003988240

消化器疾患急性閉塞性化膿性胆管炎・急性胆嚢炎 (特集救急薬剤プラクティカルガイド) -- (疾患別救急薬剤ベストプラクティス)

真弓俊彦,久保寺敏,東倫子 [他]
救急医学 35(10), 1355-1360, 2011-09
NAID 40018994423

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★リンクテーブル★

リンク元	「急性閉塞性化膿性胆管炎」「pyogenes」「化膿性」「suppuration」「pyogenic」
拡張検索	「acute suppurative tympanitis」「acute obstructive suppurative cholangitis」「intracranial suppurative thrombophlebitis」