- 関
- sulconazole
WordNet
- any compound containing the nitrate group (such as a salt or ester of nitric acid)
- treat with nitric acid, so as to change an organic compound into a nitrate; "nitroglycerin is obtained by nitrating glycerol"
PrepTutorEJDIC
- 硝酸塩 / 硝酸塩類化学肥料
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/06/02 05:24:11」(JST)
[Wiki en表示]
Sulconazole
|
Systematic (IUPAC) name |
1-(2-{[(4-chlorophenyl)methyl]sulfanyl}-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole |
Clinical data |
Trade names |
Exelderm |
AHFS/Drugs.com |
monograph |
MedlinePlus |
a698018 |
Pregnancy cat. |
? |
Legal status |
? |
Routes |
Topical |
Identifiers |
CAS number |
61318-90-9 N |
ATC code |
D01AC09 |
PubChem |
CID 5318 |
ChemSpider |
5127 Y |
UNII |
5D9HAA5Q5S Y |
KEGG |
D08535 Y |
ChEMBL |
CHEMBL1221 Y |
Chemical data |
Formula |
C18H15Cl3N2S |
Mol. mass |
397.749 g/mol |
SMILES
- Clc1ccc(c(Cl)c1)C(SCc2ccc(Cl)cc2)Cn3ccnc3
|
InChI
-
InChI=1S/C18H15Cl3N2S/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21/h1-9,12,18H,10-11H2 Y
Key:AFNXATANNDIXLG-UHFFFAOYSA-N Y
|
N (what is this?) (verify)
|
Sulconazole nitrate (trade name Exelderm) is an antifungal medication of the imidazole class. It is available as a cream or solution to treat skin infections such as athlete's foot, ringworm, jock itch, and sun fungus.[1][2]
References [edit]
- ^ Drugs.com: sulconazole topical
- ^ Fromtling, R. A. (1988). "Overview of medically important antifungal azole derivatives". Clinical Microbiology Reviews 1 (2): 187–217. PMC 358042. PMID 3069196. edit
Antifungals (D01 and J02)
|
|
Wall/
membrane |
Ergosterol
inhibitors
|
Azoles
(lanosterol 14
alpha-demethylase inhibitors)
|
Imidazoles
|
- topical: Bifonazole
- Butoconazole
- Clomidazole
- Clotrimazole#, Croconazole
- Econazole
- Fenticonazole
- Ketoconazole
- Isoconazole
- Miconazole#, Neticonazole
- Omoconazole
- Oxiconazole
- Sertaconazole
- Sulconazole
- Tioconazole
|
|
Triazoles
|
- topical: (Fluconazole#, Fosfluconazole
- Terconazole)
- systemic: (Fluconazole
- Hexaconazole
- Isavuconazole†, Itraconazole
- Posaconazole
- Voriconazole)
|
|
Thiazoles
|
topical: (Abafungin)
|
|
|
Polyene antimycotics
(ergosterol binding)
|
- topical: (Hamycin
- Natamycin
- Nystatin#)
systemic: (Amphotericin B#, Hamycin)
|
|
Allylamines
(squalene monooxygenase
inhibitors)
|
- topical: (Amorolfine
- Butenafine
- Naftifine
- Terbinafine)
systemic: (Terbinafine)
|
|
|
β-glucan synthase
inhibitors
|
- echinocandins (Anidulafungin
- Caspofungin
- Micafungin)
|
|
|
Intracellular |
Pyrimidine analogues/
Thymidylate synthase inhibitors
|
|
|
Mitotic inhibitors
|
|
|
|
Others |
- Bromochlorosalicylanilide
- Methylrosaniline
- Tribromometacresol
- Undecylenic acid
- Polynoxylin
- Chlorophetanol
- Chlorphenesin
- Ticlatone
- Sulbentine
- Ethylparaben
- Haloprogin
- Salicylic acid
- Selenium sulfide#
- Ciclopirox
- Amorolfine
- Dimazole
- Tolnaftate
- Tolciclate
- Sodium thiosulfate#
- Whitfield's ointment#
- Potassium iodide#
- Taurolidine
- Tea tree oil
- citronella oil
- lemon grass
- orange oil
- patchouli
- lemon myrtle
- PCP: Pentamidine
- Dapsone
- Atovaquone
|
|
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
|
|
UpToDate Contents
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English Journal
- Study of the enantioseparation capability of chiral dual system based on chondroitin sulfate C in CE.
- Chen J1, Du Y, Zhu F, Chen B, Zhang Q, Du S, Li P.
- Electrophoresis.Electrophoresis.2015 Feb;36(4):607-14. doi: 10.1002/elps.201300057.
- It has been reported that chiral dual system is able to improve the enantioseparation of enantiomers in many cases. Currently, the dual systems involved in CE chiral separation are mostly dual CDs systems, and the polysaccharides-based chiral dual system was reported in only one paper. To the best o
- PMID 25421375
- Enantioselective nano liquid chromatographic separation of racemic pharmaceuticals: a facile one-pot in situ preparation of lipase-based polymer monoliths in capillary format.
- Ahmed M1, Ghanem A.
- Chirality.Chirality.2014 Nov;26(11):754-63. doi: 10.1002/chir.22290. Epub 2014 Mar 6.
- New affinity monolithic capillary columns of 150 µm internal diameter were prepared in situ fused glass capillary via either immobilization or encapsulation of Candida antarctica lipase B (CALB) on or within polymer monoliths, respectively. The immobilized lipase-based monoliths were prepared via c
- PMID 24604679
- Single-walled carbon nanotube-based polymer monoliths for the enantioselective nano-liquid chromatographic separation of racemic pharmaceuticals.
- Ahmed M1, Yajadda MM2, Han ZJ2, Su D3, Wang G4, Ostrikov KK5, Ghanem A6.
- Journal of chromatography. A.J Chromatogr A.2014 Sep 19;1360:100-9. doi: 10.1016/j.chroma.2014.07.052. Epub 2014 Jul 24.
- Single-walled carbon nanotubes were encapsulated into different polymer-based monolithic backbones. The polymer monoliths were prepared via the copolymerization of 20% monomers, glycidyl methacrylate, 20% ethylene glycol dimethacrylate and 60% porogens (36% 1-propanol, 18% 1,4-butanediol) or 16.4% m
- PMID 25130087
Japanese Journal
- 1%sulconazole nitrate ソリューションによる足白癬の治療経験
- 抗真菌剤硝酸スルコナゾールのTricophyton rubrum発育菌糸の表層構造に及ぼす超微形態学的影響
- 多紀 晶子,山田 直子,内田 勝久,山口 英世,大隅 正子
- 日本医真菌学会雑誌 32(1), 31-42, 1991
- 液体培地中での皮膚糸状菌<I>Trichophyton rubrum</I>の発育菌糸の表層構造に及ぼす最小発育阻止濃度 (MIC) および部分的発育阻止濃度 (sub-MIC) のスルコナゾール (SCZ) の影響を, 低加速走査電子顕微鏡法及びフリーズレプリカ法によって検討した。<BR>走査電子顕微鏡観察から, SCZを添加して培養した場合には, 薬剤濃度に …
- NAID 130003671612
- Allergic contact dermatitis due to sulconazole nitrate, streptomycin sulfate and prednisolone valerate acetate
Related Links
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★リンクテーブル★
[★]
- 英
- sulconazole
- 化
- 硝酸スルコナゾール sulconazole nitrate
- 商
- エクセルダーム
[★]
硝酸、(化合物)硝酸塩、硝酸薬、ナイトレート、ニトロ化する
- 関
- HNO3、nitration、nitric acid
[★]
スルコナゾール
- 関
- sulconazole nitrate