WordNet

work natural fibers into a thread; "spin silk"
prolong or extend; "spin out a visit" (同)spin out
the act of rotating rapidly; "he gave the crank a spin"; "it broke off after much twisting" (同)twirl, twist, twisting, whirl
a distinctive interpretation (especially as used by politicians to sway public opinion); "the campaign put a favorable spin on the story"
a short drive in a car; "he took the new car for a spin"
a swift whirling motion (usually of a missile)
revolve quickly and repeatedly around ones own axis; "The dervishes whirl around and around without getting dizzy" (同)spin around, whirl, reel, gyrate
form a web by making a thread; "spiders spin a fine web"
make up a story; "spin a yarn"
stream in jets, of liquids; "The creek spun its course through the woods"
twist and turn so as to give an intended interpretation; "The Presidents spokesmen had to spin the story to make it less embarrassing"
of or relating to the spine or spinal cord; "spinal cord"; "spinal injury"
a bundle of sensory nerve fibers going to the thalamus (同)fillet

PrepTutorEJDIC

(羊毛などから)〈糸など〉‘を'『紡ぐ』《+『名』+『out of』+『名』〈羊毛〉》,(糸などに)〈羊毛など〉‘を'紡ぐ《+『名』〈羊毛〉+『into』+『名』》 / 〈クモ・カイコなどが〉〈糸〉‘を'『吐く』;〈巣・繭〉‘を'かける / …‘を'くるくる回す / 〈物語など〉‘を'作る,話す / 『糸を紡ぐ』;〈クモ・カイコなどが〉糸を吐く / 〈こまなどが〉くるくる回る / 〈車などが〉疾走する / 〈頭などが〉くらくらする / 〈C〉〈U〉くるくる回すこと;回転 / 〈C〉《単数形で》(車などの)一走り / 〈C〉(飛行機の)きりもみ降下 / 〈C〉《単数形で》(価値などの)急落
背骨の / せき髄麻酔

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/04/25 22:30:48」(JST)

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The spinothalamic tract (also known as anterolateral system or the ventrolateral system) is a sensory pathway from the skin to the thalamus. From the ventral posterolateral nucleus in the thalamus, sensory information is relayed upward to the somatosensory cortex of the postcentral gyrus.

The spinothalamic tract consists of two adjacent pathways: anterior and lateral. The anterior spinothalamic tract carries information about crude touch. The lateral spinothalamic tract conveys pain and temperature.

In the spinal cord, the spinothalamic tract has somatotopic organization. This is the segmental organization of its cervical, thoracic, lumbar, and sacral components, which is arranged from most medial to most lateral respectively.

The pathway decussates at the level of the spinal cord, rather than in the brainstem like the posterior column-medial lemniscus pathway and corticospinal tract.

Structure

There are two main parts of the spinothalamic tract (STT):

The lateral spinothalamic tract transmits pain and temperature.
The anterior spinothalamic tract (or ventral spinothalamic tract) transmits crude touch and firm pressure.

The spinothalamic tract, like the dorsal column-medial lemniscus tract, uses three neurons to convey sensory information from the periphery to conscious level at the cerebral cortex.

Pseudounipolar neurons in the dorsal root ganglion have axons that lead from the skin into the dorsal spinal cord where they ascend or descend one or two vertebral levels via Lissauer's tract and then synapse with secondary neurons in either the substantia gelatinosa of Rolando or the nucleus proprius. These secondary neurons are called tract cells.

The axons of the tract cells cross over (decussate) to the other side of the spinal cord via the anterior white commissure, and to the anterolateral corner of the spinal cord (hence the spinothalamic tract being part of the anterolateral system). Decussation usually occurs 1-2 spinal nerve segments above the point of entry. The axons travel up the length of the spinal cord into the brainstem, specifically the rostral ventromedial medulla.

Traveling up the brainstem, the tract moves dorsally. The neurons ultimately synapse with third-order neurons in several nuclei of the thalamus—including the medial dorsal, ventral posterior lateral, and ventral posterior medial nuclei. From there, signals go to the cingulate cortex, the primary somatosensory cortex, and insular cortex respectively.

Function

The types of sensory information transmitted via the spinothalamic tract are described as affective sensation. This means that the sensation is accompanied by a compulsion to act. For instance, an itch is accompanied by a need to scratch, and a painful stimulus makes us want to withdraw from the pain.

There are two sub-systems identified:

Direct (for direct conscious appreciation of pain)
Indirect (for affective and arousal impact of pain). Indirect projections include
- Spino-Reticulo-Thalamo-Cortical (part of the ascending reticular arousal system, aka ARAS)
- Spino-Mesencephalic-Limbic (for affective impact of pain).

Clinical significance

In contrast to the axons of second-order neurons in posterior column-medial lemniscus pathway, the axons of second-order neurons in the spinothalamic tracts cross at every segmental level in the spinal cord. This fact aids in determining whether a lesion is in the brain or the spinal cord. With lesions in the brain stem or higher, deficits of pain perception, touch sensation, and proprioception are all contralateral to the lesion. With spinal cord lesions, however, the deficit in pain perception is contralateral to the lesion, whereas the other deficits are ipsilateral. See Brown-Séquard syndrome.

Unilateral lesions usually cause contralateral anaesthesia (loss of pain and temperature). Anaesthesia will normally begin 1-2 segments below the level of lesion, affecting all caudal body areas. This is clinically tested by using pin pricks.

Anterolateral system

In the nervous system, the anterolateral system (ALS) is an ascending pathway that conveys pain,^[1] temperature (protopathic sensation), and crude touch from the periphery to the brain. It comprises three main pathways:

Name	Destination	Function
spinothalamic tract (lateral and anterior)	thalamus	important in the localization of painful or thermal stimuli
spinoreticular tract	reticular formation	causes alertness and arousal in response to painful stimuli
spinotectal tract	tectum	orients the eyes and head towards the stimuli

References

^ "Chapter 25:Neural Mechanisms of Cardiac Pain: The Anterolateral System". Retrieved 2009-11-26.

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「脊髄毛帯」

Spinothalamic tract
	Spinothalamic tracts are grouped, in blue at bottom right.
	Diagram of the principal fasciculi of the spinal cord. (Anterior and posterior spinothalamic fasciculus is labeled at bottom left.)
Details
Identifiers
Latin	Tractus spinothalamicus
NeuroNames	ancil-114
TA	A14.1.04.138
FMA	72644
	Anatomical terms of neuroanatomy [edit on Wikidata]