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capable of meeting financial obligations
a liquid substance capable of dissolving other substances; "the solvent does not change its state in forming a solution" (同)dissolvent, dissolver, dissolving agent, resolvent

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(借金の)支払い能力がある / 溶解力のある,溶かす / 溶剤,溶媒 / 解決策

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/01/28 14:00:04」(JST)

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Schematic of micellar solubilization of fatty substance in water with the use of a dispersant

Micellar solubilization (solubilization) is the process of incorporating the solubilizate (the component that undergoes solublization) into or onto micelles.^[1] Solublization may occur in a system consisting of a solvent, an association colloid (a colloid that forms micelles), and at least one other solubilizate.

Usage of the term

Solubilization is distinct from dissolution because the resulting fluid is a colloidal dispersion involving an association colloid. This suspension is distinct from a true solution, and the amount of the solubilizate in the micellar system can be different (often higher) than the regular solubility of the solubilizate in the solvent.

In non-chemical literature and in everyday language, the term "solubilization" is sometimes used^{[citation needed]} in a broader meaning as "to bring to a solution or (non-sedimenting) suspension" by any means, e.g., leaching by a reaction with an acid.

Application

Micellar solublization is widely utilized, e.g. in laundry washing using detergents, in the pharmaceutical industry, for formulations of poorly soluble drugs in solution form,^[2] and in cleanup of oil spills using dispersants.

Mechanism

Literature distinguishes two major mechanisms of solubilization process of oil by surfactant micelles, affecting the kinetics of solubilization:^[3] Surface reaction, i.e., by transient adsorption of micelles at the water-oil interface, and bulk reaction, whereby the surfactant micelles capture dissolved oil molecules.

References

^ "micellar solubilization". 2009. doi:10.1351/goldbook.M03887.
^ Jain A, Ran Y, Yalkowsky S, "Effect of pH-Sodium Lauryl Sulfate Combination on Solubilization of PG-300995 (an Anti-HIV Agent): A Technical Note." AAPS PharmSciTech. 2004; 5(3): article 45. [1]
^ P. D. Todorov, P. A. Kralchevsky, N. D. Denkov, G. Broze, and A. Mehreteab, "Kinetics of Solubilization of n-Decane and Benzene by Micellar Solutions of Sodium Dodecyl Sulfate". Journal of Colloid and Interface Science 245, 371–382 (2002), doi:10.1006/jcis.2001.8031 [2]

External links

Solubilization of Homopolymers by Block Copolymer Micelles in Dilute Solutions, J. Phys. Chem., 1995, 99 (11), pp 3723–3731, Jose R. Quintana, Ramiro A. Salazar, Issa Katime

English Journal

Studies on the sulfation of cellulose α-lipoate and ability of the sulfated product to stabilize colloidal suspensions of gold nanoparticles.

Sarbova V1, Koschella A1, Cheng F2, Kelly SM2, Heinze T3.
Carbohydrate polymers.Carbohydr Polym.2015 Jun 25;124:117-23. doi: 10.1016/j.carbpol.2015.01.080. Epub 2015 Feb 12.
A versatile method for the synthesis of cellulose α-lipoate with a low degree of substitution (DS) has been developed using N,N-dimethylacetamide (DMA)/LiCl as a solvent and N,N'-carbonyldiimidazole (CDI) as an esterification reagent. The cellulose α-lipoate with DS of α-lipoate groups of 0.26 wa
PMID 25839801

Ethnic Variability in the Expression of Hepatic Drug Transporters: Absolute Quantification by an Optimized Targeted Quantitative Proteomic Approach.

Peng KW1, Bacon J2, Zheng M3, Guo Y2, Wang MZ4.
Drug metabolism and disposition: the biological fate of chemicals.Drug Metab Dispos.2015 Apr 29. pii: dmd.115.063362. [Epub ahead of print]
Hepatic organic anion transporting polypeptides (OATPs) 1B1, 1B3 and 2B1, as well as P-glycoprotein (P-gp), play important roles in regulating liver uptake and biliary excretion of drugs. The intrinsic ethnic variability in OATP1B1-mediated hepatic uptake of statins has been proposed to underlie the
PMID 25926430

Therapeutic effect of intravesical administration of paclitaxel solubilized with poly(2-methacryloyloxyethyl phosphorylcholine-co-n-butyl methacrylate) in an orthotopic bladder cancer model.

Tamura K1, Kikuchi E2, Konno T3, Ishihara K4, Matsumoto K5, Miyajima A6, Oya M7.
BMC cancer.BMC Cancer.2015 Apr 26;15(1):317. [Epub ahead of print]
BACKGROUND: To evaluate the effects of intravesical administration of paclitaxel (PTX-30 W), which was prepared by solubilization with a water-soluble amphiphilic polymer composed of PMB30W, a copolymer of 2-methacryloyloxyethyl phosphorylcholine and n-butyl methacrylate, in an orthotopic bladder c
PMID 25928041

Japanese Journal

カーボンナノチューブの分散と分離精製

藤ヶ谷剛彦
色材協会誌 = Journal of the Japan Society of Colour Material 86(7), 252-259, 2013-07
NAID 40019752187

Highly Methyl-Branched Hydrocarbon Surfactant as a CO₂-philic Solubilizer for Water/Supercritical CO₂ Microemulsion

Sagisaka Masanobu,Kudo Kotaro,Nagoya Shota [他]
Journal of Oleo Science 62(7), 481-488, 2013-07
NAID 40019671087

スケトウダラ冷凍すり身から調製した生分解性フィルムの性状に及ぼすNaCl および各種有機酸塩添加の影響

鈴木遼,牧広樹,PORNPHATDETAUDOM AKASITH [他],古川麻美,岡惠美子,大迫一史
日本水産学会誌 79(4), 694-702, 2013
フィルム形成懸濁液中への NaCl および各種有機酸塩（クエン酸 Na，酢酸 Na，安息香酸 Na および酒石酸 Na）の添加がフィルム諸性状に与える影響について検討した。塩類で魚肉タンパク質を可溶化することにより，フィルムの表面に塩が析出した NaCl および酒石酸 Na 添加のものを除き，引っ張り強度，引っ張り伸び率および水蒸気透過性に優れ，透き通ったフィルムを得られることが明らかになった。ま …
NAID 130003364686