WordNet
- press and smooth with a heated iron; "press your shirts"; "she stood there ironing" (同)iron_out, press
- a heavy ductile magnetic metallic element; is silver-white in pure form but readily rusts; used in construction and tools and armament; plays a role in the transport of oxygen by the blood (同)Fe, atomic number 26
- implement used to brand live stock (同)branding iron
- home appliance consisting of a flat metal base that is heated and used to smooth cloth (同)smoothing iron
- a golf club that has a relatively narrow metal head
- garments (clothes or linens) that are to be (or have been) ironed; "there was a basketful of ironing to do"
- the work of using heat to smooth washed clothes in order to remove any wrinkles
- an amber, watery fluid, rich in proteins, that separates out when blood coagulates (同)blood_serum
- (of linens or clothes) smoothed with a hot iron
- metal shackles; for hands or legs (同)chains
PrepTutorEJDIC
- 〈U〉『鉄』 / 〈U〉鉄のように堅い(強い,冷たい)こと / 〈C〉鉄製の器具 / 〈C〉[電気]『アイロン』 / 〈C〉アイアン(球を打つ部分が金属のゴルフクラブ) / 〈C〉《複数形で》手かせ,足かせ / 《名詞の前にのみ用いて》『鉄の』,鉄製の / 鉄のように堅い(強い,冷たい) / …‘に'アイロンをかける / 〈人が〉アイロンをかける
- アイロンかけ / アイロンかけをした(をする)衣類
- リンパ液 / 血清
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/07/12 18:06:43」(JST)
[Wiki en表示]
Serum iron |
Medical diagnostics |
MedlinePlus |
003488 |
[edit on Wikidata]
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Serum iron is a medical laboratory test that measures the amount of circulating iron that is bound to transferrin. Clinicians order this laboratory test when they are concerned about iron deficiency, which can cause anemia and other problems.
65% of the iron in the body is bound up in hemoglobin molecules in red blood cells. About 4% is bound up in myoglobin molecules. Around 30% of the iron in the body is stored as ferritin or hemosiderin in the spleen, the bone marrow and the liver. Small amounts of iron can be found in other molecules in cells throughout the body. None of this iron is directly accessible by testing the serum.
However, some iron is circulating in the serum. Transferrin is a molecule produced by the liver that binds one or two iron(III) ions, i.e. ferric iron, Fe3+; transferrin is essential if stored iron is to be moved and used.
Most of the time, about 30% of the available sites on the transferrin molecule are filled. The test for serum iron uses blood drawn from veins to measure the iron molecules that are bound to transferrin, and circulating in the blood.
The extent to which sites on transferrin molecules are filled by iron ions can be another helpful clinical indicator, known as percent transferrin saturation. Another lab test saturates the sample to measure the total amount of transferrin; this test is called total iron-binding capacity (TIBC). These three tests are generally done at the same time, and taken together are an important part of the diagnostic process for conditions such as anemia, iron deficiency anemia, anemia of chronic disease and Haemochromatosis.
Contents
- 1 Normal values
- 2 See also
- 3 References
- 4 Further reading
Normal values
Normal reference ranges are:
- Serum Iron (SI):[1]
- Men: 65 to 176 μg/dL
- Women: 50 to 170 μg/dL
- Newborns: 100 to 250 μg/dL
- Children: 50 to 120 μg/dL
- TIBC: 240–450 μg/dL [1]
- Transferrin saturation: 20–50% [1]
μg/dL = micrograms per deciliter.
Laboratories often use different units and "normal" may vary by population and the lab techniques used; look at the individual laboratory reference values to interpret a specific test (for instance, your own).
Reference ranges for blood tests, comparing blood content of iron and related compounds (shown in brown and orange) with other constituents.
See also
References
- ^ a b c Serum Iron. University of Illinois Medical Center. Accessed July 6, 2006.
Further reading
- Medline Plus Medical Encyclopedia: Serum Iron.
- Schrier SL. Regulation of iron balance. Up-to-Date. Accessed December 5, 2005. (Requires subscription.)
Reference ranges for blood tests (CPT 82000–84999)
|
Electrolytes |
- Sodium
- Potassium
- Chloride
- Calcium
- Renal function
- Creatinine
- Urea
- BUN-to-creatinine ratio
- Plasma osmolality
- Serum osmolal gap
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Acid-base |
- Anion gap
- Arterial blood gas
- Base excess
- Bicarbonate
- CO2 content
|
Iron tests |
- Ferritin
- Serum iron
- Transferrin saturation
- Total iron-binding capacity
- Transferrin
- Transferrin receptor
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Hormones |
- ACTH stimulation test
- Thyroid function tests
- Thyroid-stimulating hormone
|
Metabolism |
|
Cardiovascular |
- Cardiac marker
- CPK-MB test
- Lactate dehydrogenase
- Myoglobin
- Glycogen phosphorylase isoenzyme BB
|
Liver function tests |
- Proteins
- Human serum albumin
- Serum total protein
- ALP
- transaminases
- Bilirubin
|
Pancreas |
|
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Antioxidant activity of olive phenols and other dietary phenols in model gastric conditions: Scavenging of the free radical DPPH and inhibition of the haem-induced peroxidation of linoleic acid.
- Achat S1, Rakotomanomana N2, Madani K1, Dangles O3.
- Food chemistry.Food Chem.2016 Dec 15;213:135-42. doi: 10.1016/j.foodchem.2016.06.076. Epub 2016 Jun 23.
- The antioxidant activity of dietary phenols in humans (direct reduction of radicals and other highly oxidizing species) could be largely restricted to fighting postprandial oxidative stress in the gastric compartment. Hence, the development of chemical tests simply modelling this situation is pertin
- PMID 27451164
- The impact of iron status and smoking on blood divalent metal concentrations in Norwegian women in the HUNT2 Study.
- Meltzer HM1, Alexander J2, Brantsæter AL2, Borch-Iohnsen B3, Ellingsen DG4, Thomassen Y4, Holmen J5, Ydersbond TA6.
- Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS).J Trace Elem Med Biol.2016 Dec;38:165-173. doi: 10.1016/j.jtemb.2016.04.008. Epub 2016 Apr 20.
- Low iron (Fe) stores may result in increased absorption of divalent metals, in particular cadmium (Cd). We have previously shown that in non-smoking women participating in the Norwegian HUNT2 cohort study this also included other divalent metals, e.g. manganese (Mn) and cobalt (Co). The diet is the
- PMID 27108098
- l-Lysine supplementation does not affect the bioavailability of copper or iron in rats.
- Bertinato J1, Lavergne C2, Vu NA3, Plouffe LJ4, Wood C5, Griffin P6, Xiao CW7.
- Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS).J Trace Elem Med Biol.2016 Dec;38:194-200. doi: 10.1016/j.jtemb.2016.02.005. Epub 2016 Feb 24.
- l-lysine (Lys) is an essential amino acid that is added to foods and dietary supplements. Lys may interact with mineral nutrients and affect their metabolism. This study examined the effect of dietary Lys supplementation on the bioavailability of copper (Cu) and iron (Fe). Weanling male Sprague-Dawl
- PMID 26968817
Japanese Journal
- Visual Assay of Total Iron in Human Serum with Bathophenanthrolin Disulfonate-accommodated MCM-41
- Predictors of Long-Term Mortality in Patients Hospitalized in an Intensive Cardiac Care Unit:A Special Role of Anemia and Iron Status
Related Links
- Serum iron is a medical laboratory test that measures the amount of circulating iron that is bound to transferrin. Clinicians order this laboratory test when they are concerned about iron deficiency, which can cause anemia and other ...
- A blood sample is needed. Iron levels are highest in the morning. Your doctor will likely have you do this test in the morning. ... Certain medicines may affect the results of this test. Your doctor will tell you if you need to ...
Related Pictures
★リンクテーブル★
[★]
- 英
- serum iron, SI
- 関
- 総鉄結合能 TIBC、鉄
概念
- 血清Feはすべてトランスフェリンに結合して存在。(LAB.580) → ということは、トランスフェリンに結合した血清中の鉄を定量していることになる。
- 健常人ではトランスフェリンの1/3がFeと結合し、残りは未結合の形で存在。(LAB.580)
- 総鉄結合能(TIBC)と血清鉄を測定し、UIBCが求めるられる。従って、検査ではTIBCとFeをオーダーすればよい。UIBCはオーダーする必要なし。
血清鉄が変動させる要因
血清鉄が変動するメカニズムで分類
- Fe濃度が高い:造血系の減退
- Fe濃度が低い:造血系の亢進
- Fe濃度が高い:肝炎などでは肝臓から貯蔵鉄が要因されて他の組織に移動する(LAB.580)。肝炎では肝細胞の破壊により鉄が放出される(←鉄は網内系に貯蔵されている)。
- Fe濃度が高い:無効造血、溶血性貧血により赤血球系細胞内に鉄が保持されず、血液中にleakする?
血清鉄の増減で分類
- 低下:鉄の喪失、需要の増大、貯蔵鉄利用不可(慢性炎症)
- 増加:鉄が過剰摂取(輸血)、需要の低下、貯蔵鉄の放出
基準値
- ♂:44-192 ug/dL (LAB)
- ♀:29-164 ug/dL (LAB)
- 41-141 ug/dL (HIM.A-6)
- 70-160 ug/dL (QB)
判定
- 高値:ヘモクロマトーシス、急性肝炎、再生不良性貧血、鉄芽球性貧血、溶血性貧血
- 低値:鉄欠乏性貧血、悪性腫瘍、膠原病などの慢性炎症、妊娠後期、子宮筋腫
その他
[★]
- 関
- iron、TIBC
[★]
鉄