WordNet

an alkaloid with anticholinergic effects that is used as a sedative and to treat nausea and to dilate the pupils in ophthalmic procedures; "transdermal scopolamine is used to treat motion sickness"; "someone sedated with scopolamine has difficulty lying" (同)hyoscine

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1. 緩和ケア：人生最後の数時間 palliative care the last hours and days of life
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The role of routinely given hyoscine-N-butylbromide in colonoscopy: a double-blind, randomized, placebo-controlled, clinical trial.

Ristikankare M1, Karinen-Mantila H1.
Scandinavian journal of gastroenterology.Scand J Gastroenterol.2016 Mar;51(3):368-73. doi: 10.3109/00365521.2015.1083611. Epub 2015 Sep 11.
OBJECTIVE: Hyoscine-N-butylbromide (HBB) has been proposed to ease colonoscopy and improve mucosal visualization, yet the results from previous studies are conflicting. In our prospective, double-blind, placebo-controlled, randomized study we aimed at evaluating whether routine administration of HBB
PMID 26554619

Murray-Brown F1, Davies IL2.
BMJ supportive & palliative care.BMJ Support Palliat Care.2015 Dec 14. pii: bmjspcare-2015-000913. doi: 10.1136/bmjspcare-2015-000913. [Epub ahead of print]
We report the case of a 60-year-old woman with metastatic breast cancer whose intractable nausea and vomiting were effectively managed with a hyoscine hydrobromide (scopolamine) patch. Contrast swallow revealed oesophageal spasm to be the underlying cause. Symptom relief may be attributed to the ant
PMID 26667134

Cholinergic Modulation of Stimulus-Specific Adaptation in the Inferior Colliculus.

Ayala YA1, Malmierca MS2.
The Journal of neuroscience : the official journal of the Society for Neuroscience.J Neurosci.2015 Sep 2;35(35):12261-72. doi: 10.1523/JNEUROSCI.0909-15.2015.
Neural encoding of an ever-changing acoustic environment is a complex and demanding process that depends on modulation by neuroactive substances. Some neurons of the inferior colliculus (IC) exhibit "stimulus-specific adaptation" (SSA), i.e., a decrease in their response to a repetitive sound, but n
PMID 26338336

加茂純子,佐宗真由美,鶴田真 [他],柏木賢治
人間ドック = Ningen dock : official journal of the Japanese Society of Human Dry Dock 22(1), 59-63, 2007-06-29
NAID 10025744616

Chronic scopolamine injection attenuated the sensitivity of temporal discrimination in rats.

畑敏道,岡市広成
心理学研究 71(6), 454-461, 2001
… The purpose of this paper is to clarify whether chronic scopolamine injection of two different doses have different effects on temporal discrimination behaviors and whether a central cholinergic blockade alters memory of stimulus duration. … After performances were stabilized in peak interval (PI) 20 s training with saline injection, rats were injected scopolamine hydrobromide 0.5 or 0.15mg/kg (n=9 or 10, respectively) intraperitoneally 15 min before training for 15 days. …
NAID 130002027723

朝日豊,田中正己,美馬和子
分析化学 35(3), 147-150, 1986-03-05
日本薬局方収載の塩化ベタネコール(I),塩酸ピロカルピン(II),臭化水素酸スコポラミン(III),臭化水素酸ホマトロピン(IV),塩酸キニーネ(V),塩酸ジブカイン(VI),塩酸プロカインアミド(VII),塩酸テトラカイン(VIII)の非水滴定法を検討した.いずれも酢酸第二水銀で前処理しなくても,無水酢酸-氷酢酸(9:1〜7:3)溶液中0.1M過塩素酸で電位差滴定しうる.第一,第二アミン(VII …
NAID 110002909302