rostral ventrolateral medulla

吻側延髄腹外側

関

RVLM

WordNet

1. the inner part of an organ or structure in plant or animal

PrepTutorEJDIC

1. 〈U〉骨髄 / =medulla oblongata

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/06/26 21:41:43」(JST)

wiki en

[Wiki en表示]

Control of blood pressure is crucially dependent on the integrity of a small region of the brainstem called the ventrolateral medulla. Within this part of the brain are the cells that control the heart, blood vessels, swallowing, breathing and many other functions of the body that are not noticed at a conscious level; such unconscious activities are known as "'Autonomic'". One of these regions is the Rostral Ventrolateral Medulla (RVLM) is also known as the pressor area of the medulla (medulla pressor). It receives inhibitory GABAergic input from the caudal ventrolateral medulla (CVLM). The RVLM is the primary regulator of the sympathetic nervous system, sending excitatory fibers (catecholaminergic) to the sympathetic preganglionic neurons in the spinal cord, via reticulospinal tract.

The RVLM is notably involved in the baroreflex.

Physostigmine, a choline-esterase inhibitor, elevates endogenous levels of acetylcholine by stimulation of the RVLM.

See also

• Vasomotor center

References

UpToDate Contents

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English Journal

• A c-fos-Monomeric Red Fluorescent Protein 1 Fusion Transgene is Differentially Expressed in Rat Forebrain and Brainstem after Chronic Dehydration and Rehydration.

• Yoshimura M, Ohkubo J, Katoh A, Ohno M, Ishikura T, Kakuma T, Yoshimatsu H, Murphy D, Ueta Y.SourceDepartment of Physiology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
• Journal of neuroendocrinology.J Neuroendocrinol.2013 May;25(5):478-87. doi: 10.1111/jne.12022.
• We have previously shown that an acute osmotic stimulation induces the expression of a c-fos and monomeric red fluorescent protein 1 (mRFP1) fusion transgene in osmosensitive rat brain areas, including the supraoptic (SON) and paraventricular nuclei (PVN). However, the effects of chronic stimuli, su
• PMID 23350545

• Redox-Sensitive Endoplasmic Reticulum Stress and Autophagy at Rostral Ventrolateral Medulla Contribute to Hypertension in Spontaneously Hypertensive Rats.

• Chao YM, Lai MD, Chan JY.SourceInstitute of Basic Medical Sciences, National Cheng Kung University, Tainan, Taiwan, Republic of China.
• Hypertension.Hypertension.2013 Apr 22. [Epub ahead of print]
• Perturbations of proper functions of the endoplasmic reticulum (ER) cause accumulation of misfolded or unfolded proteins in the cell, creating a condition known as ER stress. Prolonged ER stress has been implicated in hypertension. Oxidative stress in the rostral ventrolateral medulla (RVLM), where
• PMID 23608659

Japanese Journal

• 『高血圧は脳の異常であり治療標的は脳である』　脳・腎臓・心臓・血管連関による血圧動的恒常性維持システム

• 岸 拓弥
• 日本薬理学雑誌 145(2), 54-58, 2015
• … 中心である圧受容器反射および圧受容器反射の中枢弓であり交感神経を規定する「脳」内，特に圧受容器反射中枢弓の最終情報統合部位で交感神経中枢である頭側延髄腹外側野（rostral ventrolateral medulla：RVLM）に着目して研究を行っている．一連の研究により，圧受容器反射の中枢弓が血圧の変動・安定性維持に重要であり，さらには圧利尿においても圧と同等の作用を有するこ …
• NAID 130004827717

• Reduction of Nitric Oxide-Mediated γ-Amino Butyric Acid Release in Rostral Ventrolateral Medulla Is Involved in Superoxide-Induced Sympathoexcitation of Hypertensive Rats

• , , ,
• Circulation journal : official journal of the Japanese Circulation Society 76(12), 2814-2821, 2012-11-25
• … Background: The rostral ventrolateral medulla (RVLM) in the brainstem is responsible for regulation of the sympathetic nervous system. …
• NAID 10031126053

• Combination Therapy of Atorvastatin and Amlodipine Inhibits Sympathetic Nervous System Activation and Improves Cognitive Function in Hypertensive Rats

• ,
• Circulation journal : official journal of the Japanese Circulation Society 76(8), 1934-1941, 2012-07-25
• … Background: A previous study has demonstrated that orally administered atorvastatin reduces sympathetic nervous system (SNS) activation via an anti-oxidant in the rostral ventrolateral medulla (RVLM) of hypertensive rats, whereas amlodipine did not. …
• NAID 10030504660

Related Links

• Rostral Ventrolateral Medulla - Hypertension

Microinjection Procedures The rostral ventrolateral medulla was identified by injection of l-glutamate with stereotaxic coordinates 3.0 mm rostral, 1.8 mm lateral, and 3 mm ventral to the obex. Microinjections into the ...

• Importance of rostral ventrolateral medulla neurons in ...

1. Hypertens Res. 2012 Feb;35(2):132-41. doi: 10.1038/hr.2011.208. Epub 2011 Dec 15. Importance of rostral ventrolateral medulla neurons in determining efferent sympathetic nerve activity and blood pressure. Kumagai H, Oshima N ...

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★リンクテーブル★

リンク元	「RVLM」「吻側延髄腹外側」
関連記事	「rostral」「medulla」「ventrolateral」

「RVLM」

　　[★]

吻側延髄腹外側

関

rostral ventrolateral medulla

「吻側延髄腹外側」

　　[★]

英

rostral ventrolateral medulla、RVLM

「rostral」

　　[★]

• adj.

• 吻側の、頭側の

関

cephalad、cranial、rostrad、rostrally

「medulla」

　　[★]

毛

• 毛髄質、毛髄

副腎

• 髄質

脳神経

• 延髄

　 　

「ventrolateral」

　　[★]

• 腹外側の、腹側外側の